Targeting the intratumoral microbiota to overcome cancer immunotherapy resistance
This review delineates the mechanisms of intratumoral microbiota in cancer immunotherapy resistance, and offers strategies for microbiota‐targeted precision immunotherapy. Abstract Cancer remains a significant global health threat. The tumor microenvironment (TME) is a sophisticated ecological niche that exerts a pivotal effect on treatment outcomes ...
Bufu Tang +14 more
wiley +1 more source
Transforming transplantation science: New advanced molecular strategy to overcome corneal graft rejection. [PDF]
Al Monla R, Michon F.
europepmc +1 more source
The graphical abstract outlines a novel multifunctional ultrasound contrast agent for the diagnosis and treatment of ischemic diseases, along with innovative strategies to enhance its targeting efficiency. Abstract Ischemic diseases, such as myocardial infarction, stroke, and peripheral ischemia, are leading causes of death and disability worldwide ...
Yangyang Zhou +3 more
wiley +1 more source
Splenectomy as a Risk Factor for Graft Rejection Following Endothelial Transplantation: Retrospective Study. [PDF]
Kammrath Betancor P +4 more
europepmc +1 more source
This article explores the potential of 3D‐printed, cell‐free implants or devices for cartilage regeneration. It highlights the benefits of using biomaterial‐driven activation and modulation of ESCPs for endogenous healing of heterogeneous tissues, addressing challenges in implant design, repair mechanisms, and regulatory hurdles to create scalable ...
Liangbin Zhou +11 more
wiley +1 more source
ABSTRACT Background Cryopreserved venous allografts, which we pioneered in 1999 for use in living donor liver transplantation and hepato‐biliary‐pancreatic surgery, are widely used and are believed to preserve vascular architecture with minimal anticoagulation or immunosuppression requirements and patency comparable to autologous grafts.
Yusuke Seki +10 more
wiley +1 more source
Antibodies Against Anti-Oxidant Enzymes in Autoimmune Glomerulonephritis and in Antibody-Mediated Graft Rejection. [PDF]
Bruschi M +7 more
europepmc +1 more source
Shared genetic and molecular architecture between neurodevelopmental disorders and type 1 diabetes
Abstract Epidemiological and clinical studies have suggested possible associations between type 1 diabetes (T1D) and neurodevelopmental disorders (NDDs), but these relationships remain inconsistent across disorders and populations. To clarify whether such mixed findings, we investigated the genetic architecture linking T1D with autism spectrum disorder
Jingxuan Zhang +3 more
wiley +1 more source
Low regulatory T-cells frequency is associated with graft rejection after small bowel transplantation: Clinical and experimental evidence. [PDF]
Papa-Gobbi R +14 more
europepmc +1 more source
Early discharge after paediatric liver biopsy: A prospective observational study
Abstract Objective To evaluate the safety of early discharge after percutaneous liver biopsy (PLB) in children using prospective bleeding risk stratification. Methods In this prospective observational cohort study, paediatric patients scheduled for PLB were stratified into low‐ and high‐risk groups based on bleeding history and laboratory values.
Fie Brantbjerg Tinning +4 more
wiley +1 more source

