Results 31 to 40 of about 1,018,553 (196)

Macrophage subpopulations and their impact on chronic allograft rejection versus graft acceptance in a mouse heart transplant model

American Journal of Transplantation, 2018
Macrophages infiltrating the allografts are heterogeneous, consisting of proinflammatory (M1 cells) as well as antiinflammatory and fibrogenic phenotypes (M2 cells); they affect transplantation outcomes via diverse mechanisms.
Yue Zhao, Song Chen, P. Lan, Chenglin Wu, Yaling Dou, Xiang Xiao, Zhiqiang Zhang, L. Minze, Xiaoshun He, Wenhao Chen, Xian C. Li   +10 more
semanticscholar   +1 more source

Graft-derived cell-free DNA, a noninvasive early rejection and graft damage marker in liver transplantation: A prospective, observational, multicenter cohort study

PLoS Medicine, 2017
Background Graft-derived cell-free DNA (GcfDNA), which is released into the blood stream by necrotic and apoptotic cells, is a promising noninvasive organ integrity biomarker.
E. Schütz, A. Fischer, J. Beck, M. Harden, M. Koch, Tilo Wuensch, M. Stockmann, B. Nashan, O. Kollmar, J. Matthaei, P. Kanzow, P. Walson, J. Brockmöller, M. Oellerich   +13 more
semanticscholar   +1 more source

Risk Factors of Rejection in Renal Transplant Recipients: A Narrative Review

Journal of Clinical Medicine, 2022
Multiple factors influence graft rejection after kidney transplantation. Pre-operative factors affecting graft function and survival include donor and recipient characteristics such as age, gender, race, and immunologic compatibility.
H. Oweira, Ali Ramouz, O. Ghamarnejad, E. Khajeh, Sadeq Ali-Hasan-Al-Saegh, Rajan Nikbakhsh, C. Reissfelder, N. Rahbari, A. Mehrabi, M. Sadeghi   +9 more
semanticscholar   +1 more source

Unexplained Graft Dysfunction after Heart Transplantation—Role of Novel Molecular Expression Test Score and QTc-Interval: A Case Report

Cardiology Research and Practice, 2010
In the current era of immunosuppressive medications there is increased observed incidence of graft dysfunction in the absence of known histological criteria of rejection after heart transplantation.
Khurram Shahzad, Martin Cadeiras, Kotaro Arai, Dmitry Abramov, Elizabeth Burke, Mario C. Deng   +5 more
doaj   +1 more source

Lack of Association between Interleukin-10 Gene Polymorphisms and Graft Rejection Risk in Kidney Transplantation Recipients: A Meta-Analysis. [PDF]

PLoS ONE, 2015
Interleukin-10 (IL-10) is an important immunomodulatory cytokine. Several studies focused the association between IL-10 promoter gene polymorphisms and graft rejection risk in kidney transplantation recipients.
Jiachuan Xiong, Yiqin Wang, Ying Zhang, Ling Nie, Daihong Wang, Yunjian Huang, Bing Feng, Jingbo Zhang, Jinghong Zhao   +8 more
doaj   +1 more source

Hemostasis caused by stent-graft insertion followed by graft removal for pancreas graft bleeding due to chronic rejection: A case report

Transplantation Reports, 2022
Introduction: Lethal symptoms due to graft rejection warrant rapid removal of the transplanted graft to save the patient's life. We report a case of massive pancreas graft bleeding due to chronic rejection that necessitated graft removal after hemostasis
Kohei Miura, Takashi Kobayashi, Hirosuke Ishikawa, Seiji Saito, Yasuo Obata, Yohei Miura, Koji Toge, Yuki Hirose, Taku Ohashi, Kazuyasu Takizawa, Jun Sakata, Masayuki Tasaki, Kazuhide Saito, Yoshihiko Tomita, Toshifumi Wakai   +14 more
doaj   +1 more source

Chronic allograft rejection: A significant hurdle to transplant success

Burns & Trauma, 2014
The state-of-the-art immunosuppression drugs do not ensure indefinite transplant survival, and most transplants are continuously lost to chronic rejection even years posttransplantation.
Malgorzata Kloc, Rafik M Ghobrial
doaj   +1 more source

Characteristics of endothelial corneal transplant rejection following immunisation with SARS-CoV-2 messenger RNA vaccine

British Journal of Ophthalmology, 2021
Aim We report two cases of endothelial corneal allograft rejection following immunisation with SARS-CoV-2 messenger RNA (mRNA) vaccine BNT162b2 and describe the implications for management of transplant recipients postvaccination for COVID-19.
Maria Phylactou, Ji-Peng Olivia Li, D. Larkin   +2 more
semanticscholar   +1 more source

Graft-infiltrating host dendritic cells play a key role in organ transplant rejection

Nature Communications, 2016
Successful engraftment of organ transplants has traditionally relied on preventing the activation of recipient (host) T cells. Once T-cell activation has occurred, however, stalling the rejection process becomes increasingly difficult, leading to graft ...
Quan Zhuang, Quan Liu, S. Divito, Q. Zeng, Karim M Yatim, A. D. Hughes, Darling M. Rojas-Canales, A. Nakao, W. Shufesky, Amanda L. Williams, Rishab Humar, R. Hoffman, W. Shlomchik, M. Oberbarnscheidt, Fadi G Lakkis, A. Morelli   +15 more
semanticscholar   +1 more source

NK Cells: Not Just Followers But Also Initiators of Chronic Vascular Rejection

Transplant International
Chronic graft rejection represents a significant threat to long-term graft survival. Early diagnosis, understanding of the immunological mechanisms and appropriate therapeutic management are essential to improve graft survival and quality of life for ...
Mathilde Chambon, Alice Koenig, Alice Koenig, Alice Koenig   +3 more
doaj   +1 more source