Improved surgical technique for the establishment of a murine model of aortic transplantation. [PDF]
Aortic allotransplantation is a reliable procedure to study the evolvement of chronic rejection in mice. The progressive nature of this process in mice is characterized by diffuse and concentric myointimal proliferation which is inevitably associated ...
Aitouche, A+6 more
core +1 more source
Interleukin-2 receptor antagonists for pediatric liver transplant recipients: A systematic review and meta-analysis of controlled studies [PDF]
Interleukin-2 receptor antagonists (IL-2RA) are frequently used as induction therapy in liver transplant recipients to decrease the risk of acute rejection while allowing the reduction of concomitant immunosuppression. The exact association with the use of IL-2RA however is uncertain.
arxiv +1 more source
What have we learned about primary liver transplantation under tacrolimus immunosuppression? - Long-term follow-up of the first 1000 patients [PDF]
Objective: To summarize the long-term efficacy and safety of tacrolimus in orthotopic liver transplant (OLT) recipients, as well as to examine the factors that influence long-term morbidity and mortality rates. Background: Tacrolimus (FK506, Prograf) was
Abu-Elmagd, K+6 more
core +2 more sources
Anomalous Postselection in the Hensen et al. Bell Test [PDF]
It is shown that the data of the Hensen et al. Bell test experiment exhibits anomalous postselection that can fully account for the apparent violation of the CHSH inequality. A simulation of a local realist model implementing similar postselection is presented.
arxiv +1 more source
AIM To investigate the role of tacrolimus intra-patient variability (IPV) in adult liver-transplant recipients. METHODS We retrospectively assessed tacrolimus variability in a cohort of liver-transplant recipients and analyzed its effect on the ...
A. Del Bello+8 more
semanticscholar +1 more source
LATE ACUTE REJECTION IN LIVER TRANSPLANT: A SYSTEMATIC REVIEW
Introduction: Late acute rejection leads to worse patient and graft survival after liver transplantation. Aim: To analyze the reported results published in recent years by leading transplant centers in evaluating late acute rejection and update the ...
Lucas Souto NACIF+6 more
doaj +2 more sources
Donor-Derived Cell-Free DNA to Diagnose Graft Rejection Post-Transplant: Past, Present and Future
Donor-derived cell-free DNA (dd-cfDNA) is a non-invasive biomarker that is more sensitive and specific towards diagnosing any graft injury or rejection. Due to its applicability over all transplanted organs irrespective of age, sex, race, ethnicity, and ...
Naveen Kumar+4 more
doaj +1 more source
Non-invasive monitoring of renal transplant recipients: Urinary excretion of soluble adhesion molecules and of the complement-split product C4d [PDF]
Background: The number of inducible adhesion molecules known to be involved in cell-mediated allograft rejection is still increasing. In addition, recent data describe complement activation during acute humoral allograft rejection.
Friedrich, N.+5 more
core +1 more source
Liver graft rejection following immune checkpoint inhibitors treatment: a review
Immune checkpoint inhibitors (ICIs) have demonstrated remarkable efficacy in a variety of solid tumors; nonetheless, they have not been well investigated and are still recognized as a relative contraindication for patients with a liver transplantation ...
Bo Hu, Xiaobo Yang, X. Sang
semanticscholar +1 more source
Skin-restricted commensal colonization accelerates skin graft rejection.
Solid organ transplantation can treat end-stage organ failure, but the half-life of transplanted organs colonized with commensals is much shorter than that of sterile organs. Whether organ colonization plays a role in this shorter half-life is not known.
Y. Lei+8 more
semanticscholar +1 more source