Results 31 to 40 of about 537,363 (298)

Transcriptional Perturbations in Graft Rejection [PDF]

Transplantation, 2015
Understanding the regulatory interplay of relevant microRNAs (miRNAs) and messenger RNAs (mRNAs) in the rejecting allograft will result in a better understanding of the molecular pathophysiology of alloimmune injury.One hundred sixty-seven allograft biopsies, with (n = 47) and without (n = 120) central histology for Banff scored acute rejection (AR ...
Vitalone, Matthew J, Sigdel, Tara K, Salomonis, Nathan, Sarwal, Reuben D, Hsieh, Szu-Chuan, Sarwal, Minnie M   +5 more
openaire   +4 more sources

Coagulation and Fibrinolysis in Kidney Graft Rejection [PDF]

Frontiers in Immunology, 2020
Coagulation system is currently considered an integrated part of innate immunity. Clotting activation in response to bacterial surface along with complement cascade priming represents the first line of defense against pathogens. In the last three decades, we learned that several coagulation factors, including factor II or thrombin and factor X, can ...
Giovanni Stallone, Paola Pontrelli, Federica Rascio, Giuseppe Castellano, Loreto Gesualdo, Giuseppe Grandaliano, Giuseppe Grandaliano   +6 more
openaire   +5 more sources

Unexplained Graft Dysfunction after Heart Transplantation—Role of Novel Molecular Expression Test Score and QTc-Interval: A Case Report

Cardiology Research and Practice, 2010
In the current era of immunosuppressive medications there is increased observed incidence of graft dysfunction in the absence of known histological criteria of rejection after heart transplantation.
Khurram Shahzad, Martin Cadeiras, Kotaro Arai, Dmitry Abramov, Elizabeth Burke, Mario C. Deng   +5 more
doaj   +1 more source

HLA Antibody Incompatible Renal Transplantation: Long-term Outcomes Similar to Deceased Donor Transplantation

Transplantation Direct, 2021
Background. HLA incompatible renal transplantation still remains one of best therapeutic options for a subgroup of patients who are highly sensitized and difficult to match but not much is known about its long-term graft and patient survival.
Nithya Krishnan, MD, FRCP, Aisha Abimbola, MSc, Nandhini Machan, MSc, Sunil Daga, PhD, FRCP, Kishore Gopalakrishnan, MBBS, FRCPath, ForTai Lam, MD, FRCS, LamChin Tan, MD, FRCS, Habib Kashi, MD, FRCS, Christopher Imray, MD, FRCS, Daniel Zehnder, PhD, FRCP, Claire Collins, BSc, Rebecca Curtis, BSc, Robert Higgins, MD, FRCP, Natasha Khovanova, PhD, David Briggs, PhD   +14 more
doaj   +1 more source

Overcoming skin rejection in composite tissue allotransplantation [PDF]

, 2008
The application of composite tissue techniques is constrained by the susceptibility of skin to rejection. The aim of this thesis is to improve our understanding of skin rejection and find ways to avoid it, in order to enable expansion of the ...
Horner, B., Horner, R.
core  

Cells mediating graft rejection in the mouse. I. Lyt-1 cells mediate skin graft rejection [PDF]

, 1981
The Ly phenotype of cells mediating skin graft rejection was determined using monoclonal anti-Lyt-1.1 and Lyt-2.1 antibodies in CBA mice that received CBA lymphoid cells from mice sensitized to C57BL/6; i.e., alloantigenic differences arising from the H ...
Loveland, BE, McKenzie, IFC, Hogarth, PM, Ceredig, R   +3 more
core   +1 more source

Feeding, Fear, and Acceptance: Caregivers’ Experiences of Nutritional Support During Childhood Cancer Treatment

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose To explore caregivers' experiences and perceptions of the nutritional challenges faced by children and adolescents undergoing cancer treatment, including oral intake and the use of nutritional support. Methods This was a qualitative study based on focus groups with parents and caregivers at a Brazilian pediatric oncology hospital ...
Danyelle Apparecida Balsamão Marques, Mariana dos Santos Murra, Welinton Hirai, Ana Laura Balduino do Nascimento, Karla Emilia de Sá Rodrigues, Wilson Elias de Oliveira Junior   +5 more
wiley   +1 more source

Heparan sulfate is a plasma biomarker of acute cellular allograft rejection.

PLoS ONE, 2018
Despite advances in management of immunosuppression, graft rejection remains a significant clinical problem in solid organ transplantation. Non-invasive biomarkers of graft rejection can facilitate earlier diagnosis and treatment of acute rejection.
Andrew S Barbas, Liwen Lin, MacKenzie McRae, Andrea L MacDonald, Tracy Truong, Yiping Yang, Todd V Brennan   +6 more
doaj   +1 more source

Lack of Association between Interleukin-10 Gene Polymorphisms and Graft Rejection Risk in Kidney Transplantation Recipients: A Meta-Analysis. [PDF]

PLoS ONE, 2015
Interleukin-10 (IL-10) is an important immunomodulatory cytokine. Several studies focused the association between IL-10 promoter gene polymorphisms and graft rejection risk in kidney transplantation recipients.
Jiachuan Xiong, Yiqin Wang, Ying Zhang, Ling Nie, Daihong Wang, Yunjian Huang, Bing Feng, Jingbo Zhang, Jinghong Zhao   +8 more
doaj   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source