Results 51 to 60 of about 1,013,409 (339)

Characteristics of endothelial corneal transplant rejection following immunisation with SARS-CoV-2 messenger RNA vaccine

British Journal of Ophthalmology, 2021
Aim We report two cases of endothelial corneal allograft rejection following immunisation with SARS-CoV-2 messenger RNA (mRNA) vaccine BNT162b2 and describe the implications for management of transplant recipients postvaccination for COVID-19.
Maria Phylactou, Ji-Peng Olivia Li, D. Larkin   +2 more
semanticscholar   +1 more source

Chronic allograft rejection: A significant hurdle to transplant success

Burns & Trauma, 2014
The state-of-the-art immunosuppression drugs do not ensure indefinite transplant survival, and most transplants are continuously lost to chronic rejection even years posttransplantation.
Malgorzata Kloc, Rafik M Ghobrial
doaj   +1 more source

Current trends in single‐cell RNA sequencing applications in diabetes mellitus

FEBS Open Bio, EarlyView.
Single‐cell RNA sequencing is a powerful approach to decipher the cellular and molecular landscape at a single‐cell resolution. The rapid development of this technology has led to a wide range of applications, including the detection of cellular and molecular mechanisms and the identification and introduction of novel potential diagnostic and ...
Seyed Sajjad Zadian, Khodakaram Jahanbin, Shekoofeh Nikooei, Marzieh Rostaminejad, Arezoo Rahimi, Pedram Abdizadeh, Behnam Alipoor   +6 more
wiley   +1 more source

Lack of Association between Interleukin-10 Gene Polymorphisms and Graft Rejection Risk in Kidney Transplantation Recipients: A Meta-Analysis. [PDF]

PLoS ONE, 2015
Interleukin-10 (IL-10) is an important immunomodulatory cytokine. Several studies focused the association between IL-10 promoter gene polymorphisms and graft rejection risk in kidney transplantation recipients.
Jiachuan Xiong, Yiqin Wang, Ying Zhang, Ling Nie, Daihong Wang, Yunjian Huang, Bing Feng, Jingbo Zhang, Jinghong Zhao   +8 more
doaj   +1 more source

Graft-infiltrating host dendritic cells play a key role in organ transplant rejection

Nature Communications, 2016
Successful engraftment of organ transplants has traditionally relied on preventing the activation of recipient (host) T cells. Once T-cell activation has occurred, however, stalling the rejection process becomes increasingly difficult, leading to graft ...
Quan Zhuang, Quan Liu, S. Divito, Q. Zeng, Karim M Yatim, A. D. Hughes, Darling M. Rojas-Canales, A. Nakao, W. Shufesky, Amanda L. Williams, Rishab Humar, R. Hoffman, W. Shlomchik, M. Oberbarnscheidt, Fadi G Lakkis, A. Morelli   +15 more
semanticscholar   +1 more source

Stable, Easy‐to‐Handle, Fully Autologous Electrospun Polymer‐Peptide Skin Equivalent for Severe Burn Injuries

Advanced Functional Materials, EarlyView.
A bioengineered skin equivalent composed of electrospun poly(ε‐caprolactone) (PCL) and the bioactive peptide Fmoc‐FRGD is developed for severe burn treatment. This scaffold promotes full‐thickness skin regeneration by supporting cellular adhesion and integration. In‐vitro and in‐vivo studies show enhanced mechanical stability, accelerated wound closure,
Dana Cohen‐Gerassi, Marina BenShoshan, Adi Liiani, Tomer Reuveni, Offir Loboda, Moti Harats, Josef Haik, Itzhak Binderman, Yosi Shacham‐Diamand, Amit Sitt, Ayelet Di Segni, Lihi Adler‐Abramovich   +11 more
wiley   +1 more source

NK Cells: Not Just Followers But Also Initiators of Chronic Vascular Rejection

Transplant International
Chronic graft rejection represents a significant threat to long-term graft survival. Early diagnosis, understanding of the immunological mechanisms and appropriate therapeutic management are essential to improve graft survival and quality of life for ...
Mathilde Chambon, Alice Koenig, Alice Koenig, Alice Koenig   +3 more
doaj   +1 more source

Why do we reject a graft? Role of indirect allorecognition in graft rejection [PDF]

Kidney International, 1999
renal transplant dysfunction, as manifested by a slow, progressive rise in serum creatinine, developed; the decreasing renal function was associated with proteinuria (1 to 2 g/24 hr). The erratic cyclosporine levels and blood pressure readings led to the suspicion that he remained noncompliant with his medications.
openaire   +3 more sources

Embedded 3D‐Coaxial Bioprinting of Stenotic Brain Vessels with a Mechanically Enhanced Extracellular Matrix Bioink for Investigating Hemodynamic Force‐Induced Endothelial Responses

Advanced Functional Materials, EarlyView.
In this study, a physically enhanced vascular dECM bioink and used 3D‐coaxial bioprinting are developed to fabricate mature brain blood vessels for cerebral atherosclerosis research. This model demonstrates that vascular geometry‐induced hemodynamic changes trigger vascular inflammation, ensuring its potential for cerebrovascular research.
Wonbin Park, Min‐Ju Choi, Jae‐Seong Lee, Minjun Ahn, Wonil Han, Ge Gao, Dong‐Woo Cho, Byoung Soo Kim   +7 more
wiley   +1 more source

Killer immunoglobulin-like receptor (KIR) and HLA genotypes affect the outcome of allogeneic kidney transplantation. [PDF]

PLoS ONE, 2012
BACKGROUND: Recipient NK cells may detect the lack of recipient's (i.e., self) HLA antigens on donor renal tissue by means of their killer cell immunoglobulin-like receptors (KIRs).
Izabela Nowak, Maria Magott-Procelewska, Agnieszka Kowal, Maciej Miazga, Marta Wagner, Wanda Niepiekło-Miniewska, Małgorzata Kamińska, Andrzej Wiśniewski, Edyta Majorczyk, Marian Klinger, Wioleta Łuszczek, Andrzej Pawlik, Rafał Płoski, Ewa Barcz, David Senitzer, Piotr Kuśnierczyk   +15 more
doaj   +1 more source