Results 91 to 100 of about 316,883 (315)

Modeling Long-Term Graft Survival With Time-Varying Covariate Effects: An Application to a Single Kidney Transplant Centre in Johannesburg, South Africa

open access: yesFrontiers in Public Health, 2019
Objectives: Patients' characteristics that could influence graft survival may also exhibit non-constant effects over time; therefore, violating the important assumption of the Cox proportional hazard (PH) model.
Okechinyere J. Achilonu   +2 more
doaj   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

open access: yesMolecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker   +16 more
wiley   +1 more source

Deceased donor renal transplantation at army hospital research and referral: Our experience

open access: yesIndian Journal of Urology, 2013
Context: In India, there are a large number of end-stage renal disease (ESRD) patients waiting for renal transplant. Deceased donor organ transplantation (DDOT) is the possible solution to bridge the disparity between organ supply and demand. The concept
Yogesh Kumar Swami   +6 more
doaj   +1 more source

Human Tubular Epithelial Cells and T-cell Alloreactivity [PDF]

open access: yes, 2014
__Abstract__ Kidney transplantation is the treatment of choice for patients with end-stage renal disease. The first successful transplantation was performed in 1954 and acceptable renal allograft survival was achieved after introduction of ...
Demmers, M.W.H.J. (Martijn)
core   +1 more source

Combined liver-kidney transplantation and the effect of preformed lymphocytotoxic antibodies [PDF]

open access: yes, 1994
Thirty-eight sequentially placed liver and kidney allografts were evaluated with respect to patient and graft survival, and the influence of preformed lymphocytotoxic antibodies was analysed.
A.Jake Demetris   +34 more
core   +1 more source

Salvianolic acid-B improves fat graft survival by promoting proliferation and adipogenesis [PDF]

open access: green, 2021
Jiaming Sun   +6 more
openalex   +1 more source

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

open access: yesMolecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson   +2 more
wiley   +1 more source

Results of the kidney transplant programme at the University Clinical Centre of the Republic of Srpska from 2010 to 2018 [PDF]

open access: yesScripta Medica, 2019
Background: Kidney transplantation is the best treatment for patients with end-stage renal disease (ESRD). The aim of the study was to show the results of kidney transplantation performed in the University Clinical Centre of the Republic of Srpska in the
Grujičić Milorad   +14 more
doaj  

GRFS and CRFS in alternative donor hematopoietic cell transplantation for pediatric patients with acute leukemia. [PDF]

open access: yes, 2019
We report graft-versus-host disease (GVHD)-free relapse-free survival (GRFS) (a composite end point of survival without grade III-IV acute GVHD [aGVHD], systemic therapy-requiring chronic GVHD [cGVHD], or relapse) and cGVHD-free relapse-free survival ...
Abdel-Azim, Hisham   +53 more
core   +2 more sources

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