Results 71 to 80 of about 843,026 (292)
Tympanoplasty Outcomes in Active and Inactive Chronic Otitis Media of Mucosal Type: A Prospective Interventional Study [PDF]
Introduction: Chronic Otitis Media (COM) is a leading cause of preventable hearing loss, particularly in developing nations. It is characterised by tympanic membrane perforation and recurrent ear discharge resulting from long-standing middle ear ...
Rajeev Kumar Nishad +2 more
doaj +1 more source
Metastatic niche shaped by host factors influences disseminated cancer cell fate
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
Long-term visual and microperimetry outcomes following autologous retinal pigment epithelium choroid graft for neovascular age-related macular degeneration [PDF]
To describe the 2- to 4-year visual and microperimetry outcomes of autologous retinal pigment epithelium (RPE)-choroid graft in patients with neovascular age-related macular degeneration (AMD).In this retrospective cohort study, 12 patients with ...
Coffey, PJ +9 more
core +1 more source
Management of large tympanic membrane perforations – A comparative study
Background: This study aimed to compare the results of tympanoplasty with temporalis fascia graft alone and with composite graft in cases of inactive mucosal-type chronic suppurative otitis media with subtotal and total perforations in graft uptake and ...
Saaketh Boddupalli, Sreenivas Gouripeddi
doaj +1 more source
Comparison of graft uptake by underlay and overlay technique in myringoplasty.
About 80% of tympanic membrane tears consequential of middle ear infections or trauma restore spontaneously. Myringoplasty is the procedure to fix the perforation which fails to heal. It is of two types; overlay and underlay techniques. In former technique graft is placed lateral to the fibrous sheet of the tympanic membrane while in underlay technique
Mahwash, Khawaja +4 more
openaire +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Double Door Tympanoplasty for Management of Subtotal and Total Perforation [PDF]
Background: Chronic otitis media leads to tympanic membrane [TM] perforation which impairs hearing and predisposes to recurrent infections. Large subtotal and total perforations are challenging to repair.
Kareem Elawady +3 more
doaj +1 more source
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Context: Split thickness skin grafting (STSG) restores cutaneous cover over wounds thus protecting the underlying surface from contamination, fluid loss and stimulates healing.
Urbee Gupta +3 more
doaj +1 more source
Introduction Temporalis fascia is the commonly used graft material for tympanic membrane reconstruction. Tragal perichondrium share with the fascia the quality of being mesenchymal tissue. In our study we compared perichondrium and temporalis fascia in
Bahnisikha Kayet, Arya Brata Dubey
doaj +3 more sources

