Cutting edge strategies for diabetic wound care: Nanotechnology, bioengineering, and beyond
BMEMat, EarlyView.Graphical abstract illustrates the challenges in diabetic wound healing, covering pathophysiology, formulation hurdles, and emerging therapeutic strategies. It highlights the role of hyperglycemia, formulation complexities, and advanced technologies like bioprinting and AI in improving diabetic wound management. Abstract Diabetic wounds affect millions
Usama Ahmad +8 more
wiley +1 more source
Indirect induction of radiation lymphomas in mice. Evidence for a novel, transmissible leukemogen. [PDF]
, 1987 The transmission of a lymphomagenic agent(s) from the bone marrow of irradiated mice to thymic target cells has been demonstrated by: (a) the induction of T cell lymphomas in nonirradiated thymic grafts implanted in irradiated, Thy-l-congenic mice, (b ...
Hansteen, GA +5 more
core
Glycosaminoglycans as Polyelectrolytes: Charge, Interactions, and Applications
ChemBioChem, EarlyView.Glycosaminoglycans (GAGs) are linear, anionic biopolymers with their functions tightly linked to their charge. This review approaches GAGs from a polyelectrolyte perspective, shedding light on how the distribution of sulfate groups and, thus, negative charges, governs their interactions with other biomolecules.
Gergo Peter Szekeres +7 more
wiley +1 more source
Chronic graft-vs-host disease: Current understanding of disease and treatment landscape. [PDF]
J Manag Care Spec Pharm, 2022 Flavin B.
europepmc +1 more source
An absence of CCR5 on donor cells results in acceleration of acute graft-vs-host disease [PDF]
, 2004 Renhao Li +6 more
openalex +1 more source
Clinical Pharmacology &Therapeutics, EarlyView.Pharmacomicrobiomics is an emerging field due to important microbiome effects on pharmacokinetics and clinical outcomes. However, the application of this knowledge remains limited. Mycophenolic acid (MPA) is the primary active metabolite of the immunosuppressant, mycophenolate mofetil (MMF).
Abdelrahman Saqr +4 more
wiley +1 more source
Sirolimus and tacrolimus without methotrexate as graft-vs.-host disease prophylaxis after matched, related peripheral blood stem cell transplantation: low transplant related morbidity and excellent GVHD control [PDF]
, 2004 Corey Cutler +10 more
openalex +1 more source
Clinical Pharmacology &Therapeutics, EarlyView.Oral medications encounter gut commensal microbes that participate directly and indirectly in drug effects through metabolism, interactions with drug metabolites, or production of substrates that compete with drugs for drug‐metabolizing enzymes, consequently influencing drug pharmacokinetics.
Naomi Gronich +11 more
wiley +1 more source
Clinical Pharmacology &Therapeutics, EarlyView.Model‐informed precision dosing (MIPD) of tacrolimus in renal allograft recipients, evaluated in silico, demonstrated improved (time to and) probability of target concentration attainment and smaller deviations from target range. Using simulated tacrolimus concentration‐time profiles, a study of 200 patients was predicted to have sufficient power to ...
Dirk R.J. Kuypers +6 more
wiley +1 more source
Post-Transplant Cyclophosphamide for the Prevention of Graft-vs.-Host Disease in Allogeneic Hematopoietic Cell Transplantation: A Guide to Management for the Advanced Practitioner. [PDF]
J Adv Pract Oncol, 2023 Kachur E +4 more
europepmc +1 more source