Results 41 to 50 of about 259,309 (299)
Ubiquitination of secretory granules promotes their crinophagic degradation in Drosophila
Ubiquitination of secretory granules in Drosophila larval salivary glands is a critical molecular trigger for crinophagy, the lysosomal degradation of unreleased, or low‐quality granules. The E3 ubiquitin ligase Cnot4 is recruited to the surface of secretory granules to induce crinophagy.
Tamás Csizmadia +6 more
wiley +1 more source
Spikelet number per unit area is the most important yield component of rice (Oryza sativa L.). While spikelet number in rice is often related to total N content in whole plant, several studies have reported that it is more strongly correlated with dry ...
Masaki Okamura +6 more
doaj +1 more source
Effects of Elevated CO2 on Wheat Yield: Non-Linear Response and Relation to Site Productivity
Elevated carbon dioxide (eCO2) is well known to stimulate plant photosynthesis and growth. Elevated carbon dioxide’s effects on crop yields are of particular interest due to concerns for future food security.
Malin C. Broberg +3 more
doaj +1 more source
Impact of Climate Change on Durum Wheat Yield
Climate change will inevitably affect agriculture. Simulations of the effects of climate change on the agronomic performance (plant height, biomass dry weight, number of spikes, grain weight, harvest index, and 1000-kernel weight) of nine durum wheat ...
Erika Sabella +7 more
doaj +1 more source
Studying germplasm collection accessions of naked oats
Background. The breeding value of accessions from the VIR collection can be estimated only under specific climate and soil conditions. Studying such accessions helps to include them in the breeding process.Materials and methods.
N. V. Krotova, G. A. Batalova
doaj +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Screening and epitope characterization of Nidogen‐2‐specific nanobodies
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen +9 more
wiley +1 more source
Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner +7 more
wiley +1 more source
Grain size, grain number per panicle, and grain weight are key agronomic traits that determine grain yield in rice. However, the molecular mechanisms coordinately controlling these traits remain largely unknown.
Junrong Liu (7140248) +16 more
core +1 more source
ABSTRACT Objective To delineate specific in vivo white matter pathology in neuronal intranuclear inclusion disease (NIID) using diffusion spectrum imaging (DSI) and define its clinical relevance. Methods DSI was performed on 42 NIID patients and 38 matched controls.
Kaiyan Jiang +10 more
wiley +1 more source

