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Gram-Negative Bacterial Lysins [PDF]

Antibiotics, 2020
Antibiotics have had a profound impact on human society by enabling the eradication of otherwise deadly infections. Unfortunately, antibiotic use and overuse has led to the rapid spread of acquired antibiotic resistance, creating a major threat to public
Chandrabali Ghose, Chad W. Euler
doaj   +3 more sources

Editorial: Gram-Negative Pathogenesis [PDF]

Frontiers in Microbiology, 2021
No abstract ...
Hidetada Hirakawa, Christophe Bordi, Haruyoshi Tomita, Haruyoshi Tomita   +3 more
doaj   +4 more sources

Harnessing Gram‐negative bacteria for novel anti‐Gram‐negative antibiotics

Microbial Biotechnology
Natural products have proven themselves as a valuable resource for antibiotics. However, in view of increasing antimicrobial resistance, there is an urgent need for new, structurally diverse agents that have the potential to overcome resistance and treat
Joy Birkelbach, Carsten E. Seyfert, Sebastian Walesch, Rolf Müller   +3 more
doaj   +3 more sources

Detection of OXA-181-producing Pseudomonas aeruginosa in Germany

International Journal of Medical Microbiology, 2022
Objectives: To report the detection of the class D carbapenemase OXA-181 in an MDR clinical Pseudomonas aeruginosa isolate in Germany. Methods: Carbapenemase detection was performed by using several phenotypic tests such as the modified Hodge test, a ...
Jennifer Schauer, Sören G. Gatermann, Jessica Eisfeld, Jörg Hans, Niels Pfennigwerth   +4 more
doaj   +1 more source

A Narrative Review of Experimental Models to Study Vascular Grafts Infections

EJVES Vascular Forum, 2022
Background: Many experimental models have been developed to decipher the mechanisms of vascular graft and endograft infections (VGEIs), and to elaborate strategies to prevent or treat their occurrence.
Mathilde Puges, Fatima M'Zali, Sabine Pereyre, Cécile Bébéar, Charles Cazanave, Xavier Bérard   +5 more
doaj   +1 more source

Multicentre interlaboratory analysis of routine susceptibility testing with a challenge panel of resistant strains

Journal of Global Antimicrobial Resistance, 2022
: Objectives: In order to elaborate a new national challenge panel of resistant Gram-negative bacilli and Gram-positive cocci strains for the validation of routine antimicrobial susceptibility testing (AST) methods, an interlaboratory evaluation was ...
Corentin Deckers, Reza Soleimani, Olivier Denis, Pierre Bogaerts, Catherine Berhin, Hector Rodríguez-Villalobos, Julie Descy, Marie Hallin, Claire Nonhoff, Stefanie Desmet, Koen Magerman, Anne Marie Van den Abeele, Bénédicte Lissoir, Veerle Matheeussen, Kris Vernelen, Te-Din Huang   +15 more
doaj   +1 more source

Geographical differences of carbapenem non-susceptible Enterobacterales and Acinetobacter spp. in Germany from 2017 to 2019

Antimicrobial Resistance and Infection Control, 2022
Background Since May 2016, infection and colonisation with carbapenem non-susceptible Acinetobacter spp. (CRA) and Enterobacterales (CRE) have to be notified to health authorities in Germany. The aim of our study was to assess the epidemiology of CRA and
Anja von Laer, Tim Eckmanns, Benedikt Zacher, Niels Pfennigwerth, Sören G. Gatermann, Felix Reichert, Michaela Diercke, Gyde Steffen, Doris Altmann, Annicka Reuss   +9 more
doaj   +1 more source

In vitro Activity of Cefiderocol and Comparators against Carbapenem-Resistant Gram-Negative Pathogens from France and Belgium

Antibiotics, 2022
Infections with carbapenem-resistant (CR) Gram-negative (GN) pathogens have increased in many countries worldwide, leaving only few therapeutic options.
Saoussen Oueslati, Pierre Bogaerts, Laurent Dortet, Sandrine Bernabeu, Hend Ben Lakhal, Christopher Longshaw, Youri Glupczynski, Thierry Naas   +7 more
doaj   +1 more source

Gram-Negative Flagella Glycosylation [PDF]

International Journal of Molecular Sciences, 2014
Protein glycosylation had been considered as an eccentricity of a few bacteria. However, through advances in analytical methods and genome sequencing, it is now established that bacteria possess both N-linked and O-linked glycosylation pathways. Both glycosylation pathways can modify multiple proteins, flagellins from Archaea and Eubacteria being one ...
Susana Merino, Juan Tomás
openaire   +3 more sources

Interactions between Avibactam and Ceftazidime-Hydrolyzing Class D β-Lactamases

Biomolecules, 2020
Class D β-lactamases exhibit very heterogeneous hydrolysis activity spectra against the various types of clinically useful β-lactams. Similarly, and according to the available data, their sensitivities to inactivation by avibactam can vary by a
Jean-Marie Frère, Pierre Bogaerts, Te-Din Huang, Patrick Stefanic, Joël Moray, Fabrice Bouillenne, Alain Brans   +6 more
doaj   +1 more source