Results 21 to 30 of about 576,900 (305)
Microwave assisted antibacterial action of Garcinia nanoparticles on Gram-negative bacteria
Nature Communications, 2022 Owing to the existence of the outer membrane barrier, most antibacterial agents cannot penetrate Gram-negative bacteria and are ineffective. Here, we report a general method for narrow-spectrum antibacterial Garcinia nanoparticles that can only be ...
Yuqian Qiao +11 more
semanticscholar +1 more source
Resistance of Gram-Negative Bacteria to Current Antibacterial Agents and Approaches to Resolve It
Molecules, 2020 Antimicrobial resistance represents an enormous global health crisis and one of the most serious threats humans face today. Some bacterial strains have acquired resistance to nearly all antibiotics.
Zeinab Breijyeh +2 more
semanticscholar +1 more source
Pathogenesis of Gram-Negative Bacteremia
Clinical Microbiology Reviews, 2021 Gram-negative bacteremia is a devastating public health threat, with high mortality in vulnerable populations and significant costs to the global economy.
C. L. Holmes +3 more
semanticscholar +1 more source
Antimicrobial Resistance and Infection Control, 2022 Background Since May 2016, infection and colonisation with carbapenem non-susceptible Acinetobacter spp. (CRA) and Enterobacterales (CRE) have to be notified to health authorities in Germany. The aim of our study was to assess the epidemiology of CRA and
Anja von Laer +9 more
doaj +1 more source
Antibiotics, 2022 Infections with carbapenem-resistant (CR) Gram-negative (GN) pathogens have increased in many countries worldwide, leaving only few therapeutic options.
Saoussen Oueslati +7 more
doaj +1 more source
Gram-Negative Flagella Glycosylation [PDF]
International Journal of Molecular Sciences, 2014 Protein glycosylation had been considered as an eccentricity of a few bacteria. However, through advances in analytical methods and genome sequencing, it is now established that bacteria possess both N-linked and O-linked glycosylation pathways. Both glycosylation pathways can modify multiple proteins, flagellins from Archaea and Eubacteria being one ...
Susana Merino, Juan Tomás
openaire +3 more sources
Translational Neurodegeneration, 2021 Alzheimer’s disease (AD) is the most serious age-related neurodegenerative disease and causes destructive and irreversible cognitive decline. Failures in the development of therapeutics targeting amyloid-β (Aβ) and tau, principal proteins inducing ...
Hyeon Soo Kim +11 more
semanticscholar +1 more source
Interactions between Avibactam and Ceftazidime-Hydrolyzing Class D β-Lactamases
Biomolecules, 2020 Class D β-lactamases exhibit very heterogeneous hydrolysis activity spectra against the various types of clinically useful β-lactams. Similarly, and according to the available data, their sensitivities to inactivation by avibactam can vary by a
Jean-Marie Frère +6 more
doaj +1 more source
Antibiotics, 2021 Multidrug-resistant bacteria have on overwhelming impact on human health, as they cause over 670,000 infections and 33,000 deaths annually in the European Union alone.
L. Kakoullis +3 more
semanticscholar +1 more source
Mobile Oxazolidinone Resistance Genes in Gram-Positive and Gram-Negative Bacteria
Clinical Microbiology Reviews, 2021 Seven mobile oxazolidinone resistance genes, including cfr, cfr(B), cfr(C), cfr(D), cfr(E), optrA, and poxtA, have been identified to date. The cfr genes code for 23S rRNA methylases, which confer a multiresistance phenotype that includes resistance to ...
S. Schwarz +9 more
semanticscholar +1 more source