Results 111 to 120 of about 54,303 (272)

Quantifying Soil Microbiome Abundance by Metatranscriptomics and Complementary Molecular Techniques—Cross‐Validation and Perspectives

open access: yesMolecular Ecology Resources, EarlyView.
ABSTRACT Linking meta‐omics and biogeochemistry approaches in soils has remained challenging. This study evaluates the use of an internal RNA extraction standard and its potential for making quantitative estimates of a given microbial community size (biomass) in soil metatranscriptomics. We evaluate commonly used laboratory protocols for RNA processing,
Mathilde Borg Dahl   +22 more
wiley   +1 more source

Novel Metronidazole Conjugates as Antimicrobial Agents [PDF]

open access: yesDrug Dev Res
ABSTRACT Metronidazole (MTZ) is one of the oldest and still used anti‐infective nitroimidazole group drug. Although it is effective against anaerobic bacteria, protozoa, and parasites in clinical settings, it lacks efficacy against aerobic microorganisms.
Akgün E   +4 more
europepmc   +2 more sources

Unlocking Enhanced Efficacy of Aminoglycoside Antibiotics Against Pseudomonas aeruginosa. [PDF]

open access: yesMicrob Biotechnol
This opinion article reviews the use and challenges of aminoglycosides on the Gram‐negative pathogen Pseudomonas aeruginosa and highlights recent discoveries of adjuvants and/or other compounds that potentiate the activity of these antibiotics. ABSTRACT Infectious diseases continue to be a global health burden.
Tawiah PO, Sultana S, Dahl JU.
europepmc   +2 more sources

Dual Role of Natural Killer Cells in Early Pregnancy: Immunopathological Implications and Therapeutic Potential in Recurrent Spontaneous Abortion and Recurrent Implantation Failure

open access: yesCell Proliferation, EarlyView.
This article elaborates on the role of NK cells in early pregnancy from multiple perspectives, including molecular mechanisms and therapeutic interventions. It also discusses how NK cell dysfunction contributes to RSA and RIF, aiming to provide insights for future research on NK cell mechanisms and clinical treatment of RSA and RIF.
Defeng Guan   +5 more
wiley   +1 more source

Clothing as microbial fomites  in an equine veterinary hospital—Could interventions reduce nosocomial infection risk?

open access: yesEquine Veterinary Education, EarlyView.
Summary Background Clothing in human medical environments has been shown to be contaminated with micro‐organisms. There is little work in this area in the veterinary environment and none in equine veterinary environments. Objectives To characterise microbial contamination of veterinary clothing throughout a work shift in an equine hospital. The pattern
M. Bennett, T. Cogan, V. Roberts
wiley   +1 more source

Protein import into bacterial endosymbionts and evolving organelles

open access: yesThe FEBS Journal, EarlyView.
The acquisition of bacterial endosymbionts by ancient host cells followed by massive adaptation of the partners gave rise to mitochondria and plastids. Today, various systems with younger and less integrated endosymbionts provide insights into the initial steps in the endosymbiont to organelle transition.
Megan E. S. Sørensen   +3 more
wiley   +1 more source

Characterization and ex vivo modelling of endodontic infections from the Arabian Gulf region

open access: yesInternational Endodontic Journal, EarlyView.
Abstract Aim The microbiota of endodontic infections in patients from the Arabian Gulf region (AGR) is largely unexplored. While research in different global regions has investigated the microbial composition of such infections, studies using shotgun metagenomic sequencing (SMS) alongside culture‐dependent techniques (CDT) are limited.
Rania Nassar   +4 more
wiley   +1 more source

Antibiotic‐Induced Dysbiosis of the Gut Microbiota Shifts Host Tryptophan Metabolism and Increases the Susceptibility of Mice to Pulmonary Infection With Pseudomonas aeruginosa

open access: yesImmunology, EarlyView.
Antibiotic‐induced dysbiosis of the gut microbiota shifts host tryptophan metabolism and impairs the innate immune response during Pseudomonas aeruginosa pulmonary infection. (A) Eubiosis: During eubiosis, the intestinal microbiota metabolises tryptophan into indole metabolites, which keeps tryptophan levels within normal serum concentrations. However,
Camila Bernardo de Brito   +19 more
wiley   +1 more source

The composition of the faecal microbial flora of milking cows on feeds containing urea as the sole or partial source of nitrogen

open access: yesAgricultural and Food Science, 1980
Using a variety of culture media, counts of live bacteria in the faeces of milking cows on purified, protein-free feed in which urea was the only source of nitrogen (0-cows) and on urea-rich, low-protein feed (ULP-cows) were made. Samples were taken from
T. Ettala, A. Seuranen, M. Kreula
doaj  

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