Results 131 to 140 of about 772,298 (352)

Vm–MSI: a Vancomycin–Antimicrobial Peptide Conjugate Combating Resistant Bacteria and Broadening the Antimicrobial Spectrum

Advanced Science, EarlyView.
A series of vancomycin‐antimicrobial peptide conjugates is synthesized and evaluated to identify the optimal combination. Vm‐MSI, selected from multiple candidates, exhibited potent activity against vancomycin‐resistant and Gram‐negative bacteria by disrupting membranes and inducing oxidative stress, thereby expanding vancomycin's antibacterial ...
Shuangyu Li, Kang Wang, Wenzhuang Shi, Xu Wang, Duxin Li, Yanli Liu, Peng Zhang, Yipeng Wang   +7 more
wiley   +1 more source

Tissue‐Resident Macrophage‐Derived E3 Ligase SMURF2 Restricts Autoimmune Inflammation by Mediating the Degradation of p‐TBK1

Advanced Science, EarlyView.
Dysregulated Tissue resident macrophage (TRMs) link to autoimmune inflammation. SMURF2 mediates Lys‐27 (K27)‐linked ubiquitination of p‐TBK1 and its degradation, which inhibits CSF1R signaling‐triggered TRM proliferation, thereby restraining the autoimmune inflammation.
Xiang An, Jun Li, Lingling Wang, Chengyuan Li, Zhenpeng Jin, Yushi Yao, Minmin Jiang, Wenlong Lin, Xiaojian Wang   +8 more
wiley   +1 more source

Enhanced Efficacy of Antibiotics Supplemented with Polyamines against Gram-positive and Gram-negative Bacteria

Journal of Pure and Applied Microbiology
The dynamic drug-resistance characteristics of bacterial strains are excruciating, and various antibiotics have no discernible effect against life-threatening infections.
Resma Rajan, Md. Haroon Rashid, Brinda Goda Lakshmi Didugu, Anugata Lima, Vidyullatha Peddireddy, Anitha Mamillapalli   +5 more
doaj   +1 more source

A method to quantify viable carbapenem resistant gram-negative bacteria in treated and untreated wastewater

, 2020
Ryan Reinke, Jennipher Quach-Cu, Nigel Allison, Bellanira Lynch, Caroline Crisostomo, Michele Padilla   +5 more
openalex   +1 more source

Bacteremias in liver transplant recipients: Shift toward gram-negative bacteria as predominant pathogens† [PDF]

, 2004
Nina Singh, Marilyn M. Wagener, Asia Obman, Thomas V. Cacciarelli, Michael E. de Vera, Timothy Gayowski   +5 more
openalex   +1 more source

Tailoring Vascular‐Immune Homeostasis via Manganese‐DNA Complex‐Armed Immunogenic Extracellular Vesicles for Pancreatic Cancer Immunotherapy

Advanced Science, EarlyView.
This study demonstrates that Mn2⁺–tumor DNA complexes encapsulated in dendritic cell (DC)– derived immunogenic extracellular vesicles (EVDC@Mn‐DNA) act as a DC‐specific cGAS– STING activator. EVDC@Mn‐DNA treatment enhances intratumoral DC activation, improves tumor vascular function, promotes CD8⁺ T cell activity, and suppresses pancreatic tumor growth,
Xue Jiang, Lihuan Shang, Xiaochun Chen, Xiangzhan Kong, Xiaojuan Wang, Linjia Jiang, Huiying Zhao, Yafeng Zhu, Cheng Huang, Shiyi Deng, Rui Zhang, Minghui Wang, Haoming Lin, Ping‐Pui Wong   +13 more
wiley   +1 more source

Selectivity of Ferric Enterobactin Binding and Cooperativity of Transport in Gram-Negative Bacteria [PDF]

, 1998
Padmamalini Thulasiraman, Salete M. Newton, Jide Xu, Kenneth N. Raymond, Christine Mai, Angela Hall, Marjorie A. Montague, Phillip E. Klebba   +7 more
openalex   +1 more source

Synthesis of Electrospun TiO2 Nanofibers and Characterization of Their Antibacterial and Antibiofilm Potential against Gram-Positive and Gram-Negative Bacteria [PDF]

, 2020
Mohammad Azam Ansari, Hani Manssor Albetran, Muidh Alheshibri, A. Timoumi, N.A. Algarou, Sultan Akhtar, Y. Slimani, M.A. Almessiere, Fatimah Alahmari, A. Baykal, I.M. Low   +10 more
openalex   +1 more source

Cefepime monotherapy for the empirical treatment of fever in granulocytopenic cancer patients [PDF]

, 2017
In a pilot study, we evaluated the efficacy and the safety of cefepime, a new cephalosporin with extended-spectrum activity against both Gram-positive and Gram-negative bacteria, as empirical monotherapy for 108 febrile episodes in 84 granulocytopenic ...
Aoun, M., Calandra, T., Eggimann, P., Glauser, M. P., Meunier, F.   +4 more
core  

Neural Circuits between Nodose Ganglion and Pulmonary Neuroendocrine Cells Regulate Lung Inflammatory Responses

Advanced Science, EarlyView.
TRPA1+αCGRP+ sensory neurons in the nodose ganglion detect external insults such as lipopolysaccharide (LPS) and interact directly with pulmonary neuroendocrine cells (PNECs), promoting their activation and proliferation. This neural‐epithelial interaction amplifies lung inflammation.
Jie Chen, Shitao Xie, Zhekai Lin, Caiqi Zhao, Rujia Tao, Yingying Ma, Xiaoyan Chen, Renlan Wu, Qingjian Han, Pengfei Sui, Sheng Wang, Hongbin Ji, Hai Song, Xiaoming Zhang, Yangang Sun, Yuanlin Song, Xiao Su   +16 more
wiley   +1 more source