In this study, a novel cationic peptide, IW is designed and synthesized, with a tandem‐repeat sequence demonstrating potent activities against a broad spectrum of clinically relevant Carbapenem‐resistant Enterobacteriaceae in both the planktonic and biofilm states. IW is then formulated with P407 to form IW‐P407 colloids.
Ping Zeng+5 more
wiley +1 more source
Background: Multidrug-resistant Gram-negative bacteria (MRGN) and the infections they cause are a serious threat and a challenge to the healthcare system. This particularly applies to carbapenem-resistant Gram-negative bacteria (CRGN).
Heudorf, Ursel+9 more
doaj +1 more source
The Thing With E.coli: Highlighting Opportunities and Challenges of Integrating Bacteria in IoT and HCI [PDF]
With advances in nano- and biotechnology, bacteria are receiving increasing attention in scientific research as a potential substrate for Internet of Bio-Nano Things (IoBNT), which involve networking and communication through nanoscale and biological entities.
arxiv
Chronic obstructive pulmonary disease and asthma-associated Proteobacteria, but not commensal Prevotella spp., promote Toll-like receptor 2-independent lung inflammation and pathology [PDF]
Recent studies of healthy human airways have revealed colonization by a distinct commensal bacterial microbiota containing Gram-negative Prevotella spp.
Brix, Susanne+5 more
core +1 more source
Cell-Wall Recycling of the Gram-Negative Bacteria and the Nexus to Antibiotic Resistance.
The importance of the cell wall to the viability of the bacterium is underscored by the breadth of antibiotic structures that act by blocking key enzymes that are tasked with cell-wall creation, preservation, and regulation.
David A. Dik, J. Fisher, S. Mobashery
semanticscholar +1 more source
Peptide Display Directed Assembly of Biopolymer Core–Silica Shell Particles
Bacterial cells are engineered to produce biopolyester particles displaying peptides mediating growth of silica. Peptide‐coated biopolyester particles are treated with silica precursors and silica shell formation is studied. Transmission electron microscopy shows silica‐coated BPs which are formed after the silicification treatment. Characterization of
Deeptee Chandrashekhar Pande+2 more
wiley +1 more source
Emergence of Citrobacter freundii carrying IMP-8 metallo-β-lactamase in Germany
Metallo-β-lactamases (MBLs) in Enterobacteriaceae are an increasing problem worldwide. This report describes the isolation of Citrobacter freundii carrying IMP-8 MBL from three patients during the period from March 2012 until March 2013 in Germany.
S. Peter+7 more
doaj +1 more source
A stochastic model for bacteria-driven micro-swimmers [PDF]
Experiments have recently shown the feasibility of utilising bacteria as micro-scale robotic devices, with special attention paid to the development of bacteria-driven micro-swimmers taking advantage of built-in actuation and sensing mechanisms of cells.
arxiv
Lipopolysaccharide modification in Gram-negative bacteria during chronic infection.
The Gram-negative bacterial lipopolysaccharide (LPS) is a major component of the outer membrane that plays a key role in host-pathogen interactions with the innate immune system.
R. Maldonado, I. Sá-Correia, M. Valvano
semanticscholar +1 more source
Safety Evaluation of Repeated Application of Polymeric Microarray Patches in Miniature Pigs
This study demonstrates the safety of repeated application of three types of microarray patches (MAPs), hydrogelforming, dissolving, and implantable, over four weeks in miniature pigs. No adverse skin or systemic effects were observed, supporting the clinical potential of MAPs as safe and effective drug delivery platforms.
Qonita Kurnia Anjani+4 more
wiley +1 more source