Results 141 to 150 of about 775,898 (348)

Rational Design of Natural Xanthones Against Gram‐negative Bacteria

Advanced Science
Most antibiotics are ineffective against Gram‐negative bacteria owing to the existence of the outer membrane (OM) barrier. The rational design of compounds to expand their antibacterial spectra of antibiotics solely targeting Gram‐positive pathogens ...
Xiaojia Liu, Meirong Song, Ying Liu, Shuyu Yang, Shang Chen, Jijun Kang, Jianzhong Shen, Kui Zhu   +7 more
doaj   +1 more source

DOTA‐grafted Cationic Polymers Behaving as Powerful Macromolecular Resistance‐reversal Agents (MRRAs) Combating Against New Delhi Metallo‐β‐lactamase (NDM)‐producing Bacteria

Advanced Science, EarlyView.
Two macromolecular resistance‐reversal agents (MRRAs)—linear (MRRAL) and nanostructured (MRRAN) polymers were fabricated by integrating DOTA motifs into tunable polycationic scaffolds. MRRAs exhibit superior antibacterial potency once combined with meropenem (MEM) through (i) bacterial membrane disruption via localized cationic charge and ...
Ruixue Wang, Jian Zhang, Yun li, Liping Qiao, Zhuorui Dong, Dandan Cui, Peirong Bai, Liping Li, Bing Cao, Ruiping Zhang   +9 more
wiley   +1 more source

Prevalence of Extended Spectrum of -Lactamase Producing Gram Negative Bacteria in Septicemia Neonates in Tertiary Care Hospital

, 2015
Iosr Journals, D Israel, Bhavani Rao, P. Kamala   +3 more
openalex   +1 more source

PAF Triggered Pyroptotic NETosis Aggravates Myocardial Ischemia/Reperfusion Injury

Advanced Science, EarlyView.
Platelet activating factor (PAF) secreted by cardiomyocytes during MI/R, drives NETs formation and subsequent NETosis. PAF/NETosis signaling activation is an initiative and causal factor in driving MI/R injury. This study identifies dapagliflozin as a potent NETosis inhibitor, and demonstrates that manipulating PAF‐NETosis signal by dapagliflozin or ...
Jiawei Wu, Shule Zhang, Ruofan Du, Lina Kang, Guodong Zhao, Xue Bao, Haochi Yang, Ziqing Xie, Tianyu He, Huiyong Sun, Haiping Hao, Lijuan Cao   +11 more
wiley   +1 more source

Sulfoxides, Analogues of L-Methionine and L-Cysteine As Pro-Drugs against Gram-Positive and Gram-Negative Bacteria

, 2015
Natalya V. Anufrieva, Elena A. Morozova, Vitalia V. Kulikova, N. P. Bazhulina, И. В. Манухов, D. I. Degtev, E. Yu. Gnuchikh, А. N. Rodionov, G. B. Zavilgelsky, Tatyana V. Demidkina   +9 more
openalex   +1 more source

Wearable Battery‐Free Electrotherapy of Smartsensors for Wound Healthcare

Advanced Science, EarlyView.
Herein, we propose a simple strategy for integrating battery‐free electrotherapy wound dressings with wound sensors. Solid‐state supercapacitors constructed by PMAB with cross‐linked interpenetrating network provide energy for electrotherapy. Meanwhile, excellent mechanical sensing performance of wound dressing was used for wound assessment.
Wenrui Zhang, Qian Lin, Jiancheng Zhang, Hao Mo, Wencheng Li, Yicheng Hu, Hongting Ma, Dan Zhao, Hongnv Yu, Nan Zhu   +9 more
wiley   +1 more source

Non-Fermenting Gram Negative Bacteria as Uropathogens in Causing Urinary Tract Infection and its Antimicrobial Susceptibility Pattern at A Tertiary Care Centre of South India

, 2020
Anupam Berwal, KL Shobha, Rohit Gupta, Kriti Gupta, Asem Ali Ashraf, Abishek Kumar, Raghav Chawla, Prerna Aggarwal, Bhawna Sharma, Sonali   +9 more
openalex   +2 more sources

Identification and activity of active compound of bamboo leaves (Bambusa vulgaris Schrad ex.J.C) ethanolic extract against diabetic ulcers gram-negative bacteria from diabetic ulcer’s patient

, 2021
Pratiwi Apridamayanti
openalex   +2 more sources

Update on the Discovery of Efflux Pump Inhibitors against Critical Priority Gram-Negative Bacteria [PDF]

, 2023
Nina Compagne, Anaïs Vieira Da Cruz, Reinke T. Müller, Ruben C. Hartkoorn, Marion Flipo, Klaas M. Pos   +5 more
openalex   +1 more source

A Microbial Lipid‐ATP Synthase Axis Fuels NK Cell Antitumor Activity

Advanced Science, EarlyView.
This study focuses on the mechanism by which gut microbiota‐derived outer membrane vesicles (OMVs) regulate NK cell antitumor activity. B. intestinalis is identified to decrease extra‐intestinal tumor growth via its OMVs enriched in sphingosine (SP).
Kaiyuan Yu, Xinyu Sun, Wanxia Ma, Jianming Yang, Xuan Sun, Lisong Zhang, Yumeng Liu, Tianshu Ren, Qi Wang, Jingyu Wang, Xiao Li, Xianping Peng, Liu Yang, Junqiang Lv, Zhi Yao, Zhi‐Song Zhang, Quan Wang   +16 more
wiley   +1 more source