Prospective evaluation of risk factors and clinical influence of carbapenem resistance in children with gram-negative bacteria infection: Methodologic issues [PDF]
, 2018 Saeid Safiri, Erfan Ayubi
openalex +1 more source
Hepatocyte BDNF Acts as a Novel Immune Checkpoint to Restrain TLR4‐Mediated Acute Hepatitis
Advanced Science, EarlyView.This study identifies hepatocyte‐derived BDNF as an endogenous TLR4 antagonist that alleviates acute hepatitis. BDNF is downregulated in hepatocytes via REST‐mediated transcriptional repression during ALI/ALF. Mechanistically, BDNF binds to TLR4 on macrophages to suppress inflammation.
Weiwei Zhu +15 more
wiley +1 more source
peritoneal dialysis associated peritonitis caused by gram- negaTIVE BACTERIA
مجلة كلية الطب, 2006 Background:
aida H. Ibrahim
doaj
Advanced Science, EarlyView.A cascade‐responsive MXene@Cu‐MOF/GelMA hydrogel is engineered as a “skeleton–backpack” platform for extensive tracheal repair. The MXene framework scavenges postoperative ROS and converts NIR light into mild hyperthermia, while the Cu‐MOF component provides pH/NIR‐responsive Cu2+ dosing for infection control, angiogenesis, and chondrogenesis.
Liang Guo +8 more
wiley +1 more source
Molecular Structure of Endotoxins from Gram-negative Marine Bacteria: An Update (review) [PDF]
, 2007 A. Molinaro +5 more
core +1 more source
Trends and correlation between antibacterial consumption and carbapenem resistance in Gram-negative bacteria in a tertiary hospital in China from 2012 to 2019 [PDF]
, 2020 Chunhong Liang +5 more
openalex +1 more source
Rapid Proteome‐Wide Discovery of Protein–Protein Interactions With ppIRIS
Advanced Science, EarlyView.ppIRIS is a lightweight deep learning framework for proteome‐wide protein–protein interaction prediction directly from sequence. By fusing evolutionary and structural embeddings with a regularized Siamese architecture, ppIRIS achieves state‐of‐the‐art accuracy across species, enables minute‐scale screening, and reveals biologically validated bacterial ...
Luiz Felipe Piochi +4 more
wiley +1 more source
Evaluation of the accuracy of procalcitonin for differentiating between Gram-negative and Gram-positive bacterial sepsis in pediatric burn patients [PDF]
مجله دانشگاه علوم پزشکی گیلانBackground: Burn injuries disrupt skin integrity, increasing the risk of sepsis, a leading cause of morbidity and mortality in burn patients. Rapid differentiation between Gram-negative and Gram-positive bacterial sepsis is critical for timely and ...
Naeemeh Aghili, Sobouti
doaj
Advanced Science, EarlyView.The schematic diagram illustrates the roles of novel immune checkpoints, immunomodulatory factors, cell death and multimodal technologies in cancer immunotherapy. Abstract Cancer immunotherapy has redefined cancer treatment. However, the molecular and cellular basis of immune evasion and therapeutic resistance remains incompletely understood.
Fangquan Chen +7 more
wiley +1 more source
Multi‐Targeting Non‐Specific Genome Engineering in Bacteria
Advanced Science, EarlyView.In this study, we provide the first case to use the multi‐targeting integrase (MTI) systems in bacteria and develop a host‐independent generalizable approach, MNGE (Multi‐targeting Non‐specific Genome Engineering), for multi‐copy and random integration of metabolic genes or pathways in both Gram‐positive and Gram‐negative bacteria, which will ...
Runze Sun +7 more
wiley +1 more source