Results 171 to 180 of about 4,936,870 (299)

Novel Fluorinated Chlorhexidine Analogues Overcome Resistance in Gram-Negative Bacteria. [PDF]

ACS Omega
Li Y, Jajja M, Lu J, Chowdhury NS, Hind C, Sutton JM, Rahman KM.   +6 more
europepmc   +1 more source

Streptococcal Mannose Phosphotransferase System Component IID Is a Novel RANK‐Binding Osteoclastogenic Factor

Advanced Science, EarlyView.
Streptococcal mannose phosphotransferase system component IID (Man‐PTSIID) is identified as a novel RANK‐binding osteoclastogenic factor. By directly binding to RANK and activating NF‐κB independently of TLR2, Man‐PTSIID drives osteoclastogenesis and inflammatory bone destruction, uncovering an unexpected microbial mechanism underlying streptococcal ...
Chaeyeon Park, Yeongkag Kwon, Yeonjin Lim, Jeong Woo Park, Hyun Jung Ji, Dongwook Lee, Jueun Lee, Sung‐Ho Yun, Sungho Jeong, Ho Seong Seo, Kun Cho, Cheol‐Heui Yun, Ok‐Jin Park, Seung Hyun Han   +13 more
wiley   +1 more source

Endophthalmitis caused by gram-negative bacteria: etiologies, antibiotic susceptibilities, and treatment outcomes. [PDF]

J Ophthalmic Inflamm Infect
Pham B, Zhang C, Sanchez V, Flynn HW, Miller D.   +4 more
europepmc   +1 more source

Natural‐Inspired Engineered Microalgae With Selenium Enrichment Enabled Potent Anti‐Tumor Immunity

Advanced Science, EarlyView.
Se‐Ssp was engineered as a potent immunomodulator for activating innate immunity via the TLR and cGAS‐STING pathways, therefore converting “cold” tumors into “hot” tumors to achieve high efficacy and long‐term therapeutic outcomes. ABSTRACT Immunotherapy has shed light on clinical oncology for several decades.
Yuqi Yang, Xiaowei Cai, Xiaoyan Zhong, Tian Qiu, Qinwei Lu, Jiahao Qin, Fei Gong, Yecheng Huang, Chenyu Jiang, Youdong Chen, Yuan Cheng, Liang Cheng   +11 more
wiley   +1 more source

Selective detection of clinically relevant Gram-negative bacteria using a colistin-functionalized ISFET biosensor. [PDF]

BMC Microbiol
Nemati SS, Moniriraad M, Haeili M, Dehghan G.   +3 more
europepmc   +1 more source

Organic Nanozyme‐Embedded Biotherapeutic Thermosensitive Hydrogel for Extracellular GSH Depletion and Postoperative Tumor Suppression

Advanced Science, EarlyView.
A temperature‐sensitive hydrogel loaded with cyanine nanozymes and Escherichia coli is locally injected into postoperative tumor resection beds. Upon light irradiation, synergistic PTT and PDT work with cascaded reactive oxygen species to deplete extracellular GSH, eliminate residual tumor cells, and induce robust antitumor immune responses for ...
Cong Jiang, Zifan Yang, Rong Guo, Meng Suo, Guowei Wang, Dong Chen, Lilin Su, Fuhuan Wang, Shipeng Ning, Kelong Fan, Xuan Wang   +10 more
wiley   +1 more source

Genomic analysis of intrahospital transmission of carbapenem-resistant Gram-negative bacteria: a multicentre study in Japan. [PDF]

Microb Genom
Matsumura Y, Doi Y, Hayakawa K, Hashimoto T, Tsuda Y, Saito S, Suzuki M, Sakurai A, Shinohara K, Mori K, Uemura K, Tsuzuki S, Matono T, Itoh N, Hase R, Kato H, Mawatari M, Tsutsumi T, Yamamoto G, Tsuchido Y, Yamamoto M, Nagao M.   +21 more
europepmc   +1 more source

One‐Step Immobilized Phage Depolymerase Coatings for Catheter‐Related Bloodstream Infections

Advanced Science, EarlyView.
Catheter‐related bloodstream infections (CRBSI) caused by drug‐resistant Gram‐negative bacteria remain a major clinical challenge. Here, a polydopamine‐assisted depolymerase coating degrades bacterial capsules and restores serum‐mediated killing, effectively suppressing biofilms and reducing bacterial burden in vitro, ex vivo, and in vivo, presenting a
Lingkai Dong, Xingjin Li, Tao Hu, Qianqian Lu, Xiaoxu Zhang, Xi Chen, Yifan Luo, Zhong Zuo, Ronald Man Yeung Wong, Miao Xu, Tiancong Zhao, Sharon Shui Yee Leung   +11 more
wiley   +1 more source

A custom GPT-based model for the automated analysis and interpretation of antimicrobial susceptibility tests in Gram-negative bacteria. [PDF]

JAC Antimicrob Resist
Sprockel Díaz J, Sotomonte S, Buitrago A.   +2 more
europepmc   +1 more source

Pharmacology of currently applied antibiotics in Gram-negative bacillary bacteremia

Gram-negative bacteremia is a serious medical problem that requires treatment approaches in the growing resistance to antibiotics. There's higher fatality rates associated with bacteremia caused by multiple species of bacteria.
Edwin, Natasha Christina
core