Results 131 to 140 of about 429,807 (257)

Selective Covalent Assembly of Gram-Negative Bacteria and Synthetic Polymers into Functional Living Materials. [PDF]

J Am Chem Soc
Mohapatra O, Wang Y, Dinh MA, Li H, Rebolleda-Gomez M, Sim S.   +5 more
europepmc   +1 more source

Nanodiamonds as Bioactive Platforms to Modulate Microbial, Mammalian, and Vertebrate Systems

Advanced NanoBiomed Research, EarlyView.
Nanodiamonds (NDs) are biocompatible and antibacterial nanomaterials that support mammalian cell growth while inhibiting bacterial pathogens. NDs showed strong antibacterial activity, with Escherichia coli being more sensitive than Staphylococcus aureus. At 10 mg/mL, both bacteria exhibited ~8% viability.
Aaqil Rifai, Ayushi Priyam, Ahmed Rashed, Gebreselassie Addisu Tilaye, Kamal Poudel, Aaron G. Schultz, Richard J. Williams   +6 more
wiley   +1 more source

Synthetic O‐Polysaccharide Backbone Units for a Single Antigen Vaccine Against Two Major Non‐Typhoidal Salmonella Serovars

Angewandte Chemie, EarlyView.
A modular strategy was developed to synthesize tri‐, hexa‐, and nona‐saccharides representing repeating units of the conserved O‐polysaccharide backbone of Salmonella. Conjugates of these glycans to bacteriophage Qβ induced strong IgG responses in mice and rabbits. Antibodies elicited recognized native O‐polysaccharides and conferred protection against
Xingling Pan, Changxin Huo, Soham Maity, Herbert Kavunja, Rachel Moszyk, Cameron Talbot, Scott M. Baliban, Xuefei Huang   +7 more
wiley   +2 more sources

Transthyretin is a novel innate immune effector against Gram negative bacteria. [PDF]

PLoS Pathog
Bernabé T, Verd M, Ramis G, González-Alsina A, Qadi M, Mateu-Borrás M, Doménech-Sánchez A, Albertí S.   +7 more
europepmc   +1 more source

Human Leukocyte Elastase Triggered Nanoparticles for Targeted Antimicrobial Delivery and Oral Microbial Modulation

Advanced NanoBiomed Research, EarlyView.
This study explores enzyme‐responsive nanoparticles for targeted antimicrobial release in inflamed oral environments. Nanoparticles formed by complexing peptides and chlorhexidine respond to human leukocyte elastase and release chlorhexidine selectively. P7 (ECAAPVCE)‐based formulations show optimal properties and stability, with antimicrobial activity
Mohammed A. Hadis, Ignacio Insua, Farah N. S. Raja, Álvaro Vila, William M. Palin, Michael R. Milward, Paul R. Cooper, Sarah A. Kuehne, Owen Addison, Paco Fernandez‐Trillo   +9 more
wiley   +1 more source

Advances in BODIPY Derivatives for Antibacterial Phototherapy

Angewandte Chemie, EarlyView.
This review systematically summarizes the design strategies and structure‐activity relationships of BODIPY‐based antibacterial phototherapy, covering molecular engineering of small‐molecule photosensitizers and nanoplatforms, bacterial targeting and carrier design, and discussing the challenges and future perspectives associated with clinical ...
Li Lv, Heejeong Kim, Hongchen Zhai, Hanqi Ren, Silu Wang, Cong Sun, Yafu Wang, Hosoowi Lee, Juyoung Yoon, Hua Zhang   +9 more
wiley   +2 more sources

Surface protein machineries in Gram-negative bacteria. [PDF]

J Cell Sci
Overly Cottom C, Billings E, Bush M, DRozario D, Scherschel W, Noinaj N.   +5 more
europepmc   +1 more source

Injectable Bone Cements: A Generational Framework for Bioactivity, Porosity, and Mechanobiological Design at the Nanoscale

Advanced NanoBiomed Research, EarlyView.
Key demographic, biological, and material considerations that drive the need for advanced injectable bone cement technologies. Injectable bone cements (IBCs) are widely used in orthopaedic and craniofacial applications due to their minimally invasive delivery and ability to provide early mechanical stabilisation.
Frank Fei, Yogambha Ramaswamy, Young Jung No   +2 more
wiley   +1 more source

Peptoid-based antimicrobial strategies against polymyxin-resistant Gram-negative bacteria. [PDF]

J Appl Microbiol
Mishra SK, Shen J, Akter T, Tigabu A, Urmi UL, Damtie MA, Mekonen ES, Kuppusamy R, Sørensen K, Lin JS, Wong EHH, Hui A, Barron AE, Willcox M.   +13 more
europepmc   +1 more source

The Quantification of Drug Accumulation within Gram-Negative Bacteria. [PDF]

ACS Infect Dis
George A, Shivangi, Bozan A, Spencer K, Terlecky AJ, Ahn YM, Barnett PR, Kreiswirth BN, Freundlich JS.   +8 more
europepmc   +1 more source