Results 171 to 180 of about 772,298 (352)
Principles for Rigorous Design and Application of Synthetic Microbial Communities
Advanced Science, EarlyView.SynComs are artificially designed to enable inter‐species metabolic interactions, metabolic division of labor, and ecological interactions that can elicit phenotypes like colonization stability and environmental adaptation. This systematic review explores the processes used to construct SynComs, the assessment of the mechanisms of metabolic interaction
Yuxiao Zhang +21 more
wiley +1 more source
Surface protein machineries in Gram-negative bacteria. [PDF]
J Cell SciOverly Cottom C +5 more
europepmc +1 more source
Advanced Science, EarlyView.This study shows that Salmonella VNP20009 recruits pro‐tumor neutrophils that reduce its anticancer efficacy. Combining VNP with amodiaquine selectively eliminates these neutrophils by targeting glutathione reductase. A GR‐shRNA‐loaded VNP strain was further developed, demonstrating an innovative strategy integrating drug repurposing with synthetic ...
Wanfa Dong +13 more
wiley +1 more source
The Quantification of Drug Accumulation within Gram-Negative Bacteria. [PDF]
ACS Infect DisGeorge A +8 more
europepmc +1 more source
Microarray-Based Nucleic Acid Assay and MALDI-TOF MS Analysis for the Detection of Gram-Negative Bacteria in Direct Blood Cultures [PDF]
, 2018 Seon Young Kim +12 more
openalex +1 more source
Advanced Science, EarlyView.To distinguish how Salmonella invades cells vs how it survives long‐term, a parallel CRISPR screening platform is developed. This approach reveals the host proteins that the bacterium exploits at different stages of infection. The study identifies SORL1 as a novel host factor for invasion and demonstrates that blocking it with an antibody effectively ...
Sehee Yun +6 more
wiley +1 more source
Advanced Human Immune Cell‐Organoid Co‐Cultures for Functional Testing of Cancer Nanovaccines
Advanced Science, EarlyView.Pancreatic ductal adenocarcinoma remains difficult to treat. We establish an organoid–immune co‐culture using patient‐derived organoids and matched T‐cells to assess cancer vaccines. A mesothelin‐targeted nanovaccine activates antigen‐specific T‐cells, increases IFN‐γ, and targets MSLN+ organoids.
Nathalia Ferreira +18 more
wiley +1 more source
Aminoglycoside-Peptide Nucleic Acid (PNA) Conjugates against Gram-Negative Bacteria. [PDF]
Bioconjug ChemSiekierska I, Trylska J.
europepmc +1 more source
An Engineered Solidified Peptide Hemocyte Sponge as Nanomotor Storage to Combat Bacterial Colitis
Advanced Science, EarlyView.Peptides immobilized via nickel coordination can stabilize the framework structure. Following coating with red blood cell membranes, these constructs are capable of continuously sequestering endotoxins and mitigating colonic pathogenic damage by alleviating bacterial‐induced ferroptosis.
Yuxin Fang +8 more
wiley +1 more source
The threat of carbapenem-resistant gram-negative bacteria in a Middle East region
, 2018 Effat Davoudi-Monfared, Hossein Khalili
openalex +2 more sources