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Leukotoxins of gram-negative bacteria
Veterinary Microbiology, 2002Leukotoxins are a group of exotoxins that produce their primary toxic effects against leukocytes, especially polymorphonuclear cells (PMNs). Leukotoxins include a variety of chemicals ranging from 9,10-epoxy 12-octadecenoate, a fatty acid derivative secreted by leukocytes themselves, to proteins such as RTX (repeats in toxin).
Sanjeev Kumar, Narayanan +3 more
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Antibiotic uptake into gram-negative bacteria
European Journal of Clinical Microbiology & Infectious Diseases, 1988Antibiotics taken up into gram-negative bacteria face two major diffusion barriers, the outer and cytoplasmic membranes. Of these, the former has been most studied and is discussed in detail here. Evidence from antibiotic MIC studies on porin-deficient mutants compared with their porin-sufficient parent strains has provided strong support for the ...
R E, Hancock, A, Bell
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Resistance mechanisms in Gram-negative bacteria
Medicina Intensiva (English Edition), 2022Enterobacterales resistant to carbapenems or producing extended-spectrum β-lactamases (ESBL) and non-fermenters resistant to carbapenems present resistance to many of the antimicrobials commonly used in clinical practice, and have been recognized by the World Health Organization as a critical priority for the development of new antimicrobials.
Lepe, José A. +1 more
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2009
Gram-negative bacteria are responsible for a broad array of infections in both the ambulatory and hospital settings. Urinary tract infections, otitis media, pneumonia, abdominal infections, and meningitis are among the common and serious diseases caused by these pathogens. Beta-lactams including penicillins, cephalosporins, monobactams, and carbapenems,
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Gram-negative bacteria are responsible for a broad array of infections in both the ambulatory and hospital settings. Urinary tract infections, otitis media, pneumonia, abdominal infections, and meningitis are among the common and serious diseases caused by these pathogens. Beta-lactams including penicillins, cephalosporins, monobactams, and carbapenems,
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Isolating DNA from Gram-Negative Bacteria
Cold Spring Harbor Protocols, 2017The isolation of DNA from bacteria, described in this protocol, relies upon the use of sodium dodecyl sulfate and proteinase K to lyse the cells. High-molecular-weight DNA is then sheared (to reduce its viscosity and make it more manageable), extracted with phenol:chloroform, and precipitated with isopropanol.
Michael R, Green, Joseph, Sambrook
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Resistance in gram-negative bacteria: Enterobacteriaceae
American Journal of Infection Control, 2006The emergence and spread of resistance in Enterobacteriaceae are complicating the treatment of serious nosocomial infections and threatening to create species resistant to all currently available agents. Approximately 20% of Klebsiella pneumoniae infections and 31% of Enterobacter spp infections in intensive care units in the United States now involve ...
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Gram-negative brewery bacteria
2003Brewing bacteriology was born when microorganisms responsible for the spoilage of beer were investigated by Lotus Pasteur in his classic nineteenth- century study. He was called upon to determine why French beer was inferior to German beer. He isolated a number of bacterial contaminants from French beer and malt wort and in 1876 published his famous ...
Hennie J. J. Van Vuuren +1 more
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Emerging Gram-negative bacteria
Current Opinion in Pulmonary Medicine, 2018The current review examines the current literature around 'emerging' Gram-negative bacteria other than Pseudomonas aeruginosa in cystic fibrosis (CF), paying particular focus on the recent literature for those that are more frequently encountered: Pandoraea, Achromobacter, Ralstonia and Stenotrophomonas species.The recent literature is evolving our ...
Heather, Green, Andrew M, Jones
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Corneal Rings With Gram-Negative Bacteria
Archives of Ophthalmology, 1977Corneal rings have been described with corneal ulcerations caused by Gram-negative bacteria. Corneal rings were produced by intracorneal injections of viable Pseudomonas aeruginosa as well as heat-inactivated suspensions of Gram-negative bacteria (P aeruginosa and Escherichia coli) but not Gram-positive bacteria (Staphylococcus aureus) or Freund's ...
B J, Mondino +4 more
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Detecting Gram-negative bacteria
Science Signaling, 2015Eukaryotic cells use the host protein TIFA to sense the monosaccharide HBP, derived from Gram-negative bacteria.
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