Results 31 to 40 of about 4,936,870 (299)

In Vitro Activities of Colistin and Sitafloxacin Combinations against Multidrug-, Carbapenem-, and Colistin-Resistant Acinetobacter baumannii Using the Broth Microdilution Checkerboard and Time-Kill Methods

open access: yesAntibiotics, 2020
Drug-resistant Acinetobacter baumannii (A. baumannii) infections are a critical global problem, with limited treatment choices. This study aims to determine the in vitro activities of colistin–sitafloxacin combinations against multidrug-, carbapenem- and
Vipavee Rodjun   +6 more
doaj   +1 more source

Oligonucleotide recombination in Gram-negative bacteria [PDF]

open access: yesMolecular Microbiology, 2010
This report describes several key aspects of a novel form of RecA-independent homologous recombination. We found that synthetic single-stranded DNA oligonucleotides (oligos) introduced into bacteria by transformation can site-specifically recombine with bacterial chromosomes in the absence of any additional phage-encoded functions.
Bryan, Swingle   +5 more
openaire   +2 more sources

Callistemon linearis Schrad. and J.C. Wendl. Extracts Inhibit the Growth of Gram-Positive Bacteria but have no Effect on Gram Negative Bacteria

open access: yes, 2019
Introduction: The development of multi-antibiotic resistant strains of bacteria has necessitated the search for new effective antibacterial therapies. Many Callistemon spp.
Cock, Ian Edwin   +2 more
core   +1 more source

Five-year period evaluation of isolated agents and their resistance profiles in intensive care unit patients with malignancy

open access: yesJournal of Infection in Developing Countries, 2020
Introduction: Patients treated in the intensive care unit (ICU) are usually patients who deteriorated health condition and could have longer hospital stay compared to other patients. Hospital infections are more common in ICU patients.
Duygu Mert   +6 more
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Regulation of innate and adaptive immune responses by Gram-positive and Gram-negative bacteria [PDF]

open access: yes, 2009
Bacteria are classified as Gram-positive or Gram-negative, depending on their cell wall structure. The role of the bacterial cell wall in immune regulation is the focus of the current work.
Martner, Anna
core   +1 more source

Prolonged carriage of OXA-244-carbapenemase-producing Escherichia coli complicates epidemiological investigations

open access: yesInternational Journal of Medical Microbiology
The rapid increase of OXA-244-producing Escherichia coli, predominantly driven by genetically clustered isolates of sequence type (ST)38, has been observed in at least nine European countries, including Germany. However, the reasons for the spread of OXA-
Felix Reichert   +8 more
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

The first report of the coproduction of CMY-16 and ArmA 16S rRNA methylases in carbapenemase-ESBL producing Escherichia coli isolates

open access: yesEuropean Journal of Biological Research, 2020
The main aim of this work was to assess the occurrence and to characterize AmpC genes and to investigate the co-existence of 16S rRNA methylases and carbapenemases genes among the ESBL producing Escherichia coli strains.
Meriem Meriem Meziani   +3 more
doaj  

Molecular Characterization of CarbapenemaseProducing Gram-negative Bacteria Isolated from Clinical Specimens in Baghdad, Iraq

open access: yes, 2019
The emergence and spread of carbapenem-resistant Gram-negative bacteria is a worldwide emerging public health threat responsible for large number of nosocomail infections.
Saad L. Hamed, Noor A. Hasoon
core   +1 more source

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