Results 91 to 100 of about 430,389 (345)

Treatment Options for Carbapenem-resistant Gram-negative Bacterial Infections [PDF]

Clinical Infectious Diseases, 2019
AbstractAntimicrobial resistance has become one of the greatest threats to public health, with rising resistance to carbapenems being a particular concern due to the lack of effective and safe alternative treatment options. Carbapenem-resistant gram-negative bacteria of clinical relevance include the Enterobacteriaceae, Pseudomonas aeruginosa ...
openaire   +2 more sources

Co‐Electrospinning Extracellular Matrix with Polycaprolactone Enables a Modular Approach to Balance Bioactivity and Mechanics of a Multifunctional Bone Wrap

Advanced Healthcare Materials, EarlyView.
The incorporation of nondigested ECM and synthetic polymers into a co‐electrospinning system enables the decoupling of bioactivity and mechanical properties within a single wrap. This technique is used to develop a multifunctional bone wrap that achieves augmented membrane durability, sustained infection control, and enhanced vascularity for use in ...
Sarah Jones, Madeline Laude, Zeenat Oyebanji, Ruchi Birur, Andres Luengo Martinez, Isabelle Gilbert, Phillip Baek, Nichole Longbottom, Nicole McCullough, Staci J. Horn, Chien‐Yu Lin, Matthew J. Lohr, Fred Clubb, Manuel K. Rausch, Elizabeth Cosgriff‐Hernandez   +14 more
wiley   +1 more source

Burden of Multidrug-Resistant Gram-Negative Bacterial Infections in a Tertiary Care Hospital

Journal of Pure and Applied Microbiology
Multidrug-resistant (MDR) Gram-negative bacterial infections have emerged as a major public health concern. The aim of the present study was to detect the rate of infections due to MDR Gram-negative bacteria (GNB) in a tertiary care hospital, the rate of
V. Kavya, Rashmi P. Mahale, R. Deepashree, A. Nidha Jamal   +3 more
doaj   +1 more source

Outcome of infections due to pandrug-resistant (PDR) Gram-negative bacteria

BMC Infectious Diseases, 2005
Background The increasing problem of infections due to multidrug-resistant Gram-negative bacteria has led to re-use of polymyxins in several countries.
Bliziotis Ioannis A, Kasiakou Sofia K, Falagas Matthew E, Samonis George, Athanassopoulou Panayiota, Michalopoulos Argyris   +5 more
doaj   +1 more source

Controversies in the Use of Passive Immunotherapy for Bacterial Infections in the Critically Ill Patient [PDF]

, 2017
Several preparations of standard immunoglobulins for intravenous use have been tested as adjunctive therapy for bacterial infections in premature neonates and in critically ill adults after major surgery, trauma, and burn.
Baumgartner, J. D., Glauser, M. P.
core  

Host Inactivation of Bacterial Lipopolysaccharide Prevents Prolonged Tolerance Following Gram-Negative Bacterial Infection [PDF]

Cell Host & Microbe, 2008
A transient state of tolerance to microbial molecules accompanies many infectious diseases. Such tolerance is thought to minimize inflammation-induced injury, but it may also alter host defenses. Here we report that recovery from the tolerant state induced by Gram-negative bacteria is greatly delayed in mice that lack acyloxyacyl hydrolase (AOAH), a ...
Lu, Mingfang, Varley, Alan W., Ohta, Shoichiro, Hardwick, John, Munford, Robert S.   +4 more
openaire   +2 more sources

Multiscale Hybrid Surface Topographies Orchestrate Immune Regulation, Antibacterial Defense, and Tissue Regeneration

Advanced Healthcare Materials, EarlyView.
Hybrid wrinkled topographies coordinate immune, tissue, and bacterial interactions. The surfaces promote osteointegration, tune macrophage polarization, and inhibit biofilm formation, highlighting a multifunctional strategy for next‐generation implant design.
Mohammad Asadi Tokmedash, Jacob Robins, J. Scott VanEpps, Minji Kim, Jouha Min   +4 more
wiley   +1 more source

Six-year retrospective analysis of the epidemiology and risk factors of multidrug-resistant bloodstream infections in oncology patients in Jiangxi, China

Microbiology Spectrum
Cancer patients are particularly vulnerable to bloodstream infections (BSIs) due to their immunocompromised status. This retrospective study at Jiangxi Cancer Hospital (2019 to 2024) analyzed the bacterial spectrum, risk factors, and antimicrobial ...
Bin Xu, Xunsong Wang, Xiaohui Li, Muhammad Nadeem Khan, Muhammad Shafiq, Sabir Khan, Tenghua Yu, Rahat Ullah Khan, Ying Song, Hanman Qiu, Qiao-Li Lv, Hazrat Bilal   +11 more
doaj   +1 more source

A multifunctional platform with single-NIR-laser-triggered photothermal and NO release for synergistic therapy against multidrug-resistant Gram-negative bacteria and their biofilms

Journal of Nanobiotechnology, 2020
Background Infectious diseases caused by multidrug-resistant (MDR) bacteria, especially MDR Gram-negative strains, have become a global public health challenge.
Baohua Zhao, He Wang, Wenjing Dong, Shaowen Cheng, Haisheng Li, Jianglin Tan, Junyi Zhou, Weifeng He, Lanlan Li, Jianxiang Zhang, Gaoxing Luo, Wei Qian   +11 more
doaj   +1 more source

Airborne Multidrug-Resistant Bacteria Isolated from a Concentrated Swine Feeding Operation [PDF]

, 2004
The use of nontherapeutic levels of antibiotics in swine production can select for antibiotic resistance in commensal and pathogenic bacteria in swine. As a result, retail pork products, as well as surface and groundwaters contaminated with swine waste ...
Amy Chapin, Ana Rule, Jensen LB, Kellogg Schwab, Kristen Gibson, Mackiewicz B, Timothy Buckley, Zahn JA   +7 more
core   +2 more sources