Results 11 to 20 of about 430,389 (345)

Effectiveness and safety of cefiderocol treatment in patients with Gram-negative bacterial infections in Spain in the early access programme: results of the PERSEUS study. [PDF]

open access: hybridEur J Clin Microbiol Infect Dis
Torre-Cisneros J   +12 more
europepmc   +3 more sources

Netilmicin in Gram-Negative Bacterial Infections [PDF]

open access: yesAntimicrobial Agents and Chemotherapy, 1979
Netilmicin, a new semisynthetic aminoglycoside, was used in the treatment of 42 patients with serious gram-negative bacterial infections. Of the 40 evaluable patients, 24 (60%) were cured, and 8 (20%) had a favorable clinical response, for a total clinical response rate of 80%.
D R, Snydman   +4 more
openaire   +2 more sources

A host-directed macrocyclic peptide therapeutic for MDR gram negative bacterial infections

open access: yesScientific Reports, 2021
The emergence of infections by carbapenem resistant Enterobacteriaceae (CRE) pathogens has created an urgent public health threat, as carbapenems are among the drugs of last resort for infections caused by a growing fraction of multi-drug resistant (MDR)
Justin B. Schaal   +9 more
doaj   +1 more source

TFPI-2 Protects Against Gram-Negative Bacterial Infection [PDF]

open access: yesFrontiers in Immunology, 2018
Tissue factor pathway inhibitor-2 (TFPI-2) has previously been characterized as an endogenous anticoagulant. TFPI-2 is expressed in the vast majority of cells, mainly secreted into the extracellular matrix. Recently we reported that EDC34, a C-terminal peptide derived from TFPI-2, exerts a broad antimicrobial activity. In the present study, we describe
Mohamad N. Ali   +12 more
openaire   +6 more sources

Innovative Antibiotic Therapies for Carbapenem-Resistant Gram-Negative Bacterial Infections: Clinical Efficacy, Safety, and Comparative Studies. [PDF]

open access: goldMicroorganisms
Eslami M   +8 more
europepmc   +3 more sources

Emergence of Pan-drug resistance amongst gram negative bacteria! The First case series from India [PDF]

open access: yesJournal of Microbiology and Infectious Diseases, 2014
Objective: Increasing prevalence of carbapenem resistant Gram negative bacteria is a serious clinical and public health challenge. Bacteria resistant to all available antibiotics (Pan Drug Resistance) herald the onset of post antibiotics era. We hereby
Abdul Ghafur   +4 more
doaj   +1 more source

Prevalence of bacterial bloodstream infections and association between neutropenia and 30-day mortality among oncology inpatients at a university hospital in Saudi Arabia

open access: yesAnnals of Saudi Medicine, 2023
BACKGROUND: Cancer patients are highly prone to develop bacterial bloodstream infections (BSI) and are also at risk of neutropenia. Knowledge of the prevalence of these infections and whether neutropenia is associated with a change in mortality is ...
Khalifa Binkhamis   +7 more
doaj   +1 more source

Potential strategies for the eradication of multi-drug resistant Gram-negative bacterial infections [PDF]

open access: yes, 2016
Antimicrobial resistance is one of the leading threats to society. The increasing burden of multidrug-resistant Gram-negative infection is particularly concerning as such bacteria are demonstrating resistance to nearly all currently licensed therapies ...
Gilmore, Brendan F.   +3 more
core   +1 more source

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