Increased rate of multidrug-resistant gram-negative bacterial infections in hospitalized immunocompromised pediatric patients. [PDF]
Khafaja S +13 more
europepmc +3 more sources
Netilmicin in Gram-Negative Bacterial Infections [PDF]
Netilmicin, a new semisynthetic aminoglycoside, was used in the treatment of 42 patients with serious gram-negative bacterial infections. Of the 40 evaluable patients, 24 (60%) were cured, and 8 (20%) had a favorable clinical response, for a total clinical response rate of 80%.
D R, Snydman +4 more
openaire +2 more sources
Effectiveness and safety of cefiderocol treatment in patients with Gram-negative bacterial infections in Spain in the early access programme: results of the PERSEUS study. [PDF]
Torre-Cisneros J +12 more
europepmc +3 more sources
A host-directed macrocyclic peptide therapeutic for MDR gram negative bacterial infections
The emergence of infections by carbapenem resistant Enterobacteriaceae (CRE) pathogens has created an urgent public health threat, as carbapenems are among the drugs of last resort for infections caused by a growing fraction of multi-drug resistant (MDR)
Justin B. Schaal +9 more
doaj +1 more source
TFPI-2 Protects Against Gram-Negative Bacterial Infection [PDF]
Tissue factor pathway inhibitor-2 (TFPI-2) has previously been characterized as an endogenous anticoagulant. TFPI-2 is expressed in the vast majority of cells, mainly secreted into the extracellular matrix. Recently we reported that EDC34, a C-terminal peptide derived from TFPI-2, exerts a broad antimicrobial activity. In the present study, we describe
Mohamad N. Ali +12 more
openaire +6 more sources
Emergence of Pan-drug resistance amongst gram negative bacteria! The First case series from India [PDF]
Objective: Increasing prevalence of carbapenem resistant Gram negative bacteria is a serious clinical and public health challenge. Bacteria resistant to all available antibiotics (Pan Drug Resistance) herald the onset of post antibiotics era. We hereby
Abdul Ghafur +4 more
doaj +1 more source
BACKGROUND: Cancer patients are highly prone to develop bacterial bloodstream infections (BSI) and are also at risk of neutropenia. Knowledge of the prevalence of these infections and whether neutropenia is associated with a change in mortality is ...
Khalifa Binkhamis +7 more
doaj +1 more source
Innovative Antibiotic Therapies for Carbapenem-Resistant Gram-Negative Bacterial Infections: Clinical Efficacy, Safety, and Comparative Studies. [PDF]
Eslami M +8 more
europepmc +3 more sources
Objective. Due to the fact that K. variicola, K. quasipneumoniae and K. pneumoniae are closely related bacterial species, misclassification can occur due to mistakes either in normal biochemical tests or during submission to public databases.
Esperanza Martínez-Romero +6 more
doaj +1 more source
Background: In developing countries, ocular infections are a significant public health concern, particularly bacterial infections, which are common. This research aimed to estimate how often Gram-positive and negative bacteria are present in individuals ...
Mukal Assaad Hussein +3 more
doaj +1 more source

