Carbapenem-Resistant Gram-Negative Bacterial Infections in Children
Antimicrobial Agents and Chemotherapy, 2020 Carbapenem-resistant organisms (CRO) are a major global public health threat. Enterobacterales hydrolyze almost all β-lactams through carbapenemase production. Infections caused by CRO are challenging to treat due to the limited number of antimicrobial options. This leads to significant morbidity and mortality. Over
Aguilera-Alonso, David +4 more
openaire +4 more sources
Clinics, 2016 OBJECTIVES: Delay in the treatment of pleural infection may contribute to its high mortality. In this retrospective study, we aimed to evaluate the diagnostic accuracy of pleural adenosine deaminase in discrimination between Gram-negative and Gram ...
Ruolin Li +3 more
doaj +1 more source
Rates of Multidrug-Resistant Gram-Negative Bacterial Infections in Hospitalized Non-Immunocompromised Pediatric Patients: A 9-Year Retrospective Study at a Lebanese Tertiary Medical Center. [PDF]
Infect Drug ResistZakhour R +22 more
europepmc +3 more sources
Differential regulation of CCL-11/eotaxin-1 and CXCL-8/IL-8 by Gram-positive and Gram-negative bacteria in human airway smooth muscle cells [PDF]
, 2008 Background: Bacterial infections are a cause of exacerbation of airway disease. Airway smooth muscle cells (ASMC) are a source of inflammatory cytokines/chemokines that may propagate local airway inflammatory responses.
Chung, KF +5 more
core +2 more sources
Metabolites, 2023 Lipidomics analyses of bacteria offer the potential to detect and monitor infections in a host since many bacterial lipids are not present in mammals. To evaluate this omics approach, we first built a database of bacterial lipids for representative Gram ...
Paul L. Wood, Erdal Erol
doaj +1 more source
Presence of multiple bacterial markers in clinical samples might be useful for presumptive diagnosis of infection in cirrhotic patients with culture-negative reports [PDF]
, 2016 Bacterial infections in cirrhotic patients with ascites are associated with a severe prognosis and an increased risk of death. The microbiological standard tests for the diagnosis of suspected infection, based on culture test of blood and ascitic fluid ...
Boaretti, M +4 more
core +1 more source
Cefiderocol: A Review in Serious Gram-Negative Bacterial Infections [PDF]
Drugs, 2021 Intravenous cefiderocol (Fetroja®; Fetcroja®) is the first siderophore cephalosporin approved for the treatment of adults with serious Gram-negative bacterial infections. Cefiderocol is stable against all four Ambler classes of β-lactamases (including metallo-β-lactamases) and exhibits excellent in vitro activity against many clinically relevant Gram ...
openaire +2 more sources
Lactoferrin. A natural glycoprotein involved in iron and inflammatory homeostasis [PDF]
, 2017 Human lactoferrin (hLf), an iron-binding multifunctional cationic glycoprotein secreted by exocrine glands and by neutrophils, is a key element of host defenses.
Cutone, Antimo +4 more
core +5 more sources
mBio, 2021 Gram-negative bacteria include a number of pathogens that cause disease in humans and animals. Although antibiotics are still effective in treating a considerable range of infections caused by Gram-negative bacteria, the alarming increase of ...
Zhuang Zhu +3 more
doaj +1 more source
Enrofloxacin-based therapeutic strategy for the prevention of endometritis in susceptible mares [PDF]
, 2010 Enrofloxacin (EFX) is often used empirically to prevent uterine infections in mares in order to improve efficiency on Commercial Embryo Transfer Farms.
Confalonieri, Alejandra +7 more
core +1 more source