Results 31 to 40 of about 806,507 (311)

Synthesis and evaluation of halogenated nitrophenoxazinones as nitroreductase substrates for the detection of pathogenic bacteria [PDF]

open access: yes, 2013
The synthesis and microbiological evaluation of 7-, 8- and 9-nitro-1,2,4-trihalogenophenoxazin-3-one substrates with potential in the detection of nitroreductase-expressing pathogenic microorganisms are described.
Alexandre F. Bedernjak   +6 more
core   +1 more source

Antimicrobial potential of Streptomyces sp. to the Gram positive and Gram negative pathogens

open access: yesJournal of Infection and Public Health, 2019
Background: The occurrence of drug resistant infectious disease causing microbial pathogens was highly spreaded because of the wide level application of the commercially available antimicrobial agents.
Mysoon Al-Ansari   +3 more
doaj   +1 more source

Constitutive activation of two-component systems reveals regulatory network interactions in Streptococcus agalactiae

open access: yesNature Communications
Bacterial two-component systems (TCSs) are signaling modules that control physiology, adaptation, and host interactions. A typical TCS consists of a histidine kinase (HK) that activates a response regulator via phosphorylation in response to ...
Cosme Claverie   +12 more
doaj   +1 more source

Antimicrobial Resistance Profiles in Enterococcus spp. Isolates From Fecal Samples of Wild and Captive Black Capuchin Monkeys (Sapajus nigritus) in South Brazil

open access: yesFrontiers in Microbiology, 2018
The environment, human, and animals play an important role in the spread of antibiotic-resistant bacteria. Enterococci are members of the gastrointestinal tracts of humans and animals and represent important reservoirs of antibiotic resistance genes ...
Tiela Trapp Grassotti   +8 more
doaj   +1 more source

Efficacy and Tolerability of Topotecan/Cyclophosphamide/Dinutuximab in Relapsed and Refractory High‐Risk Neuroblastoma: A Multi‐Institutional Retrospective Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Chemoimmunotherapy with irinotecan, temozolomide, and dinutuximab (I/T/DIN) has emerged as first‐line therapy for relapsed/refractory (r/r) high‐risk neuroblastoma (HRNB) in North America. Topotecan and cyclophosphamide (T/C) are often used in combination with dinutuximab in the setting of lack of response, progression, or incomplete ...
Benjamin J. Lerman   +17 more
wiley   +1 more source

Antimicrobial and anti-biofilm activity of Hypericum brasiliense extract and its fractions on Staphylococcus of canine origin

open access: yesScientific Reports
The growing resistance to antimicrobials, partly due to the ability to form biofilms, poses a challenge for developing new antimicrobial agents. This study assessed the antimicrobial and antibiofilm activity of Hypericum brasiliense extract, Japonicin ...
Yasmim de M. Assumpção   +9 more
doaj   +1 more source

Induction of intercrypt goblet cells upon bacterial infection: a promising therapeutic target to restore the mucosal barrier

open access: yesGut Microbes
Intestinal mucins play a crucial role in the mucosal barrier, serving as the body’s initial defense against microorganisms. However, how the host regulates the secretion and glycosylation of these mucins in response to bacterial invasion remains unclear.
Renaud Léonard   +10 more
doaj   +1 more source

Draft genome sequence of enterococcus faecalis strain CECT7121, a corn silage isolate with antibacterial activity against gram-positive pathogens [PDF]

open access: yes, 2019
Enterococcus faecalis CECT7121 is a corn silage probiotic bacterium that shows antibacterial activity against Gram-positive pathogens from different origins. Its genome sequence is 2.9 Mb long with a GC content of 37.3%.
Delpech, Gastón   +3 more
core   +1 more source

The Efficacy and Safety of Bevacizumab/Irinotecan/Temozolomide (BIT) for Relapsed/Refractory Neuroblastoma: The UK Children's Cancer and Leukaemia Group Experience

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Patients with high‐risk neuroblastoma who either are refractory to induction chemotherapy or relapse following multi‐modal treatment have a dismal prognosis. Based on data from the BEACON trial, since 2021 the UK national guidelines recommend bevacizumab, irinotecan, and temozolomide (BIT) for patients with relapsed/refractory ...
Thomas J. Jackson   +20 more
wiley   +1 more source

ANTIBACTERIAL ASSAY OF 2’-HYDROXY-4’,6’,4-TRIMETHOXYCHALCONE AND 4-METHOXYCHALCONE AGAINST GRAM POSITIVE AND GRAM NEGATIVE BACTERIA

open access: yesJurnal Riset Kesehatan, 2019
Blood transfusion is currently one of the most important health care treatments. Unfortunately, the prevalence of transfusion reactions caused by the use of blood products is still quite high although blood products have been tested in terms of ...
Wiwit Sepvianti   +1 more
doaj   +1 more source

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