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Resistance mechanisms of Gram-positive bacteria
The introduction and increasing use of antibiotics for antibacterial therapy has initiated a rapid development and expansion of antibiotic resistance in microorganisms, particularly in human pathogens. Additionally, a shift to an increase in number and severity of Gram-positive infections has been observed the last decades. Common to these pathogens is
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The human gut microbiome across the life course
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
Background: Antibiotic resistance has become quite a challenge in the treatment of bacterial infections in the world. Therefore, the present study was conducted with the aim of investigating the pattern of antibiotic resistance among microorganisms ...
Mohammad Ali Davarpanah +1 more
doaj +1 more source
Introduction: The development of multi-antibiotic resistant strains of bacteria has necessitated the search for new effective antibacterial therapies. Several Grevillea spp.
Cock, Ian Edwin
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Results of linear mixed models examining effects of earthworm species, the different earthworm density addition, and the nested density of earthworm species on soil microorganism biomasses including total microorganism, bacteria, fungi, the ratio of gram-
Yongfan Cheng (16851525) +6 more
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We first identified functional murine mitochondrial N‐formyl peptides (MT‐FPs) and investigated their effects on the in vitro myeloid‐derived suppressor cell (MDSC) generation from bone marrow cells. We demonstrated that MT‐FPs acted directly on bone marrow cells to promote MDSC generation and modulated the polymorphonuclear (PMN)‐MDSC/monocyte (M ...
Miyako Ozawa +2 more
wiley +1 more source
Theoretical evaluation of wall teichoic acids in the cavitation-mediated pores formation in Gram-positive bacteria subjected to an electric field [PDF]
Background: Electroporation is a method of choice to transform living cells. The ability of electroporation to transfer small or large chemicals across the lipid bilayer membrane of eukaryotic cells or Gram-negative bacteria relies on the formation of ...
Rauch, Cyril, Leigh, James A.
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Neurodegenerative Disease Treatment Drug PBT2 Breaks Intrinsic Polymyxin Resistance in Gram-Positive Bacteria [PDF]
Gram-positive bacteria do not produce lipopolysaccharide as a cell wall component. As such, the polymyxin class of antibiotics, which exert bactericidal activity against Gram-negative pathogens, are ineffective against Gram-positive bacteria.
Lisa Bohlmann +53 more
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New quinolones and gram-positive bacteria [PDF]
The quinolone class of antibacterial agents has evolved rapidly to emerge as one of the most effective classes of drugs in the treatment of infectious diseases. While the spectra and antibacterial activities of fluoroquinolones, such as ciprofloxacin, developed in the 1980s improved to include most gramnegative bacteria, their activities against gram ...
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Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta +7 more
wiley +1 more source

