Results 251 to 260 of about 423,873 (294)

Daptomycin Therapy for Invasive Gram-Positive Bacterial Infections in Children

Pediatric Infectious Disease Journal, 2007
Clinical improvement is often delayed among children with invasive infections caused by multidrug resistant Gram-positive bacteria such as methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant enterococci (VRE) despite use of standard antimicrobial therapy.
Monica I, Ardura, Asunción, Mejías, Kathy S, Katz, Paula, Revell, George H, McCracken, Pablo J, Sánchez   +5 more
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Therapy of Gram-Positive Bacterial Infections

Veterinary Clinics of North America: Small Animal Practice, 1988
This article considers the important features of gram-positive bacteria that relate to chemotherapy and the clinical pharmacology of the drugs of choice for treating these infections.
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Glycopeptides and Antibiotics for Gram-positive Bacterial Infections

2016
Glycopeptides, lipopeptides and other antibiotics, such as linezolid and quinupristin/dalfopristin , are exclusively used for the treatment of infections caused by Gram-positive bacteria. Limited information is available about the dosing of these antibiotics in obese patients.
Syed Tabish R. Zaidi, Brett Janson
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Benefit-Risk Assessment of Linezolid for Serious Gram-Positive Bacterial Infections

Drug Safety, 2008
Linezolid is an oxazolidinone, a new class of antibacterial with a unique mechanism of action, namely inhibition of the formation of a functional 70S initiation complex in the 50S bacterial ribosomal subunit. Linezolid is highly active against multidrug-resistant Gram-positive cocci, including meticillin-resistant Staphylococcus aureus (MRSA ...
Matthew E, Falagas, Konstantinos Z, Vardakas   +1 more
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Antibiotic candidates for Gram-positive bacterial infections induce multidrug resistance

Science Translational Medicine
Several antibiotic candidates are in development against Gram-positive bacterial pathogens, but their long-term utility is unclear. To investigate this issue, we studied the laboratory evolution of resistance to antibiotics that have not yet reached the market.
Martins, Ana, Judák, Fanni, Farkas, Zoltán, Szili, Petra, Grézal, Gábor, Csörgő, Bálint, Czikkely, Márton Simon, Maharramov, Elvin, Daruka, Lejla, Spohn, Réka, Balogh, Dávid, Daraba, Andreea, Juhász, Szilvia, Vágvölgyi, Máté, Hunyadi, Attila, Cao, Yihui, Sun, Zhenquan, Li, Xuechen, Papp, Balázs, Pál, Csaba   +19 more
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Polysaccharide Conjugate Vaccines for the Prevention of Gram-Positive Bacterial Infections

1996
Among the most problematic Gram-positive bacteria with regard to human pathology are Staphylococcal species including S. aureus and S. epidermidis, Enterococcal species including E. faecalis and E. faecium, and Streptococcus species including S. pneumoniae and Group B Streptococcus, among others.
R, Naso, A, Fattom
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Antibiotics for gram-positive bacterial infections: vancomycin, quinupristin-dalfopristin, linezolid, and daptomycin

Infectious Disease Clinics of North America, 2004
An overview of the mechanism of action, dosing, clinical indications, and toxicities of the glycopeptide vancomycin is provided. Emerging gram-positive bacterial resistance to antimicrobials and its mechanisms are reviewed. Strategies to control emergence of resistance are proposed.
Tammy S, Lundstrom, Jack D, Sobel
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Nosocomial Gram‐positive bacterial infections in children: Results of a 7 year study

Pediatrics International, 2007
AbstractBackground: The aim of the present paper was to determine the rate of culture‐proven nosocomial infections and evaluate the episodes of nosocomial Gram‐positive (GP) bacterial infections in pediatric patients.Methods: The data of children with positive culture, who were diagnosed as having nosocomial infection on the Centers for Disease ...
Ozakin, CÜNEYT, Hacimustafaoglu, MUSTAFA KEMAL, Ozdemir, Ozlem, Celebi, Solmaz   +3 more
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Neurodegeneration in models of Gram-positive bacterial infections of the central nervous system

Biochemical Society Transactions, 2007
Gram-positive bacterial infections of the central nervous system, such as meningitis, induce an extensive inflammatory response, which in turn may damage neurons. LTA (lipoteichoic acid) is a component of the Gram-positive bacterial cell wall that induces glial inflammatory activation in vitro and in vivo.
J J, Neher, G C, Brown
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[Gram-positive bacterial infections resistant to antibiotic treatment].

Annali italiani di medicina interna : organo ufficiale della Societa italiana di medicina interna, 2002
Antibiotic resistance has become a major problem in the treatment of gram-positive bacterial infections. These organisms are able to escape antibiotic activity through several mechanisms including beta-lactamase production, altered penicillin-binding proteins, aminoglycoside-modifying enzymes, modification of the target site of the antibiotic, and ...
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