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Glycopeptides and Antibiotics for Gram-positive Bacterial Infections
2016Glycopeptides, lipopeptides and other antibiotics, such as linezolid and quinupristin/dalfopristin , are exclusively used for the treatment of infections caused by Gram-positive bacteria. Limited information is available about the dosing of these antibiotics in obese patients.
Syed Tabish R. Zaidi, Brett Janson
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Polysaccharide Conjugate Vaccines for the Prevention of Gram-Positive Bacterial Infections
1996Among the most problematic Gram-positive bacteria with regard to human pathology are Staphylococcal species including S. aureus and S. epidermidis, Enterococcal species including E. faecalis and E. faecium, and Streptococcus species including S. pneumoniae and Group B Streptococcus, among others.
R, Naso, A, Fattom
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Drosophila MyD88 is required for the response to fungal and Gram-positive bacterial infections
Nature Immunology, 2001We report here the identification and functional characterization of DmMyD88, a gene encoding the Drosophila homolog of mammalian MyD88. DmMyD88 combines a Toll-IL-1R homology (TIR) domain and a death domain. Overexpression of DmMyD88 was sufficient to induce expression of the antifungal peptide Drosomycin, and induction of Drosomycin was markedly ...
Tauszig-Delamasure, Servane +4 more
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Benefit-Risk Assessment of Linezolid for Serious Gram-Positive Bacterial Infections
Drug Safety, 2008Linezolid is an oxazolidinone, a new class of antibacterial with a unique mechanism of action, namely inhibition of the formation of a functional 70S initiation complex in the 50S bacterial ribosomal subunit. Linezolid is highly active against multidrug-resistant Gram-positive cocci, including meticillin-resistant Staphylococcus aureus (MRSA ...
Matthew E, Falagas +1 more
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Neurodegeneration in models of Gram-positive bacterial infections of the central nervous system
Biochemical Society Transactions, 2007Gram-positive bacterial infections of the central nervous system, such as meningitis, induce an extensive inflammatory response, which in turn may damage neurons. LTA (lipoteichoic acid) is a component of the Gram-positive bacterial cell wall that induces glial inflammatory activation in vitro and in vivo.
J J, Neher, G C, Brown
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Miscellaneous Gram-Positive Bacterial Infections
2021Joshua B. Daniels, Jane E. Sykes
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Real-world effectiveness of dalbavancin for invasive gram-positive bacterial infections
American Journal of Health-System PharmacyAbstract Purpose Emerging data suggest dalbavancin may be used in complicated infections, including bacteremia, prosthetic joint infections, osteomyelitis, and endovascular infections. This study aimed to evaluate the real-world safety and effectiveness of dalbavancin for the treatment of ...
Jake Crocker +9 more
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ANTIBIOTICS FOR GRAM-POSITIVE BACTERIAL INFECTIONS
Infectious Disease Clinics of North America, 2000Tammy S. Lundstrom, Jack D. Sobel
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[Gram-positive bacterial infections resistant to antibiotic treatment].
Annali italiani di medicina interna : organo ufficiale della Societa italiana di medicina interna, 2002Antibiotic resistance has become a major problem in the treatment of gram-positive bacterial infections. These organisms are able to escape antibiotic activity through several mechanisms including beta-lactamase production, altered penicillin-binding proteins, aminoglycoside-modifying enzymes, modification of the target site of the antibiotic, and ...
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