Results 121 to 130 of about 262,573 (317)
Grammaticalization and grammar
, 1992 This paper is concerned with developing Joan Bybee's proposals regarding the nature of grammatical meaning and synthesizing them with Paul Hopper's concept of grammar as emergent. The basic question is this: How much of grammar may be modeled in terms of
Himmelmann, Nikolaus P.
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Nucleic Acid Therapeutics for “Undruggable” Cancer Targets: Mechanisms, Challenges, and Prospects
Advanced Science, EarlyView.Nucleic acid therapeutics bypass the structural limitations of conventional drugs by targeting mRNA rather than proteins. This review examines how antisense oligonucleotides, siRNAs, miRNAs, aptamers, and mRNA vaccines intervene against historically undruggable oncoproteins including Ras, MYC, and p53, highlighting mechanistic advances, delivery ...
Feng Xu +6 more
wiley +1 more source
Students and the teaching of Arabic grammar at Jordanian schools
The main purpose of this study is to explore the reasons for students' weaknesses in grammar at Jordanian schools, taking as an example the upper basic stage (ages 14-16 years) in the Al-karak district.
Al-Qudah, Hatem Ahmed
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A construction grammar account of possessive constructions in Lancashire dialect : some advantages and challenges. [PDF]
, 2007 This study investigates reduction of 1SG possessives in possessive–noun constructions in Lancashire dialect. On the basis of a corpus of twenty-six interviews we show that reduction patterns according to (in)alienability.
Siewierska, Anna, Hollmann, Willem B.
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Frontiers in Public HealthBackgroundWith the rapid development of global digital economy, burnout among food delivery riders has become an important public health issue. Although burnout has been widely studied, research on burnout among food delivery riders, particularly the ...
Jian Dong, Guoyong Zhang, Lizhi Wu
doaj +1 more source
Advanced Science, EarlyView.Stem cell differentiation follows a conserved surface condensate trajectory: H3K27ac super enhancers nucleate large RNA polymerase II clusters that grow and unfold before transcriptional activity disperses them. This work reveals how biophysical forces at enhancer surfaces dynamically build and dismantle stem cell transcription hubs, reshaping cell ...
Tim Klingberg +18 more
wiley +1 more source
Advanced Science, EarlyView.A brain‐targeted nanoparticle enables delivery of a therapeutic nanobody (Nb.29E9) that inhibits pathogenic GSK3β signaling. This intervention restores AMPK/mTORC1/TGFβ homeostasis, attenuates neuroinflammation and oxidative stress, and promotes long‐term functional recovery after ischemic stroke.
Lan Li +14 more
wiley +1 more source
Love Grammar: Student-driven Grammar Learning Games
, 2010 The words "grammar learning" and "boring" are often, unfortunately, associated. Traditional grammar teaching and learning fails to engage students in active and lifelong learning.
Natolo, Michelle +1 more
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Descriptive adequacy in Functional Grammar [PDF]
, 2001 Este artículo sostiene que la adecuación descriptiva de la GF abarca tanto hechos tipológicos como otros propios de las lenguas particulares. Para ilustrar este argumento, se pone a prueba una jerarquía semántica que predice el uso de formas verbales ...
Hengeveld, K.; id_orcid +4 more
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Biodegradable Zn‐Based Implants: Progress, Challenges, and Pathways toward Clinical Translation
Advanced Science, EarlyView.Exploring biodegradable Zn‐based implants offers a promising pathway to next‐generation biomedical devices with balanced degradation and biocompatibility. A comprehensive overview of biodegradable Zn‐based implants, covering their biological significance, material design principles, and advanced engineering strategies is provided.
Panfeng Zhao +10 more
wiley +1 more source