Current Challenges of Transcription Compartmentalization Research
Transcription factors, coactivators, and RNA polymerase II assemble into transcription compartments ranging from small, defined complexes to liquid‐like condensates. This review unifies these seemingly competing descriptions along a single continuum and asks what these compartments have been shown to do, and what they have not, revealing that the most ...
Thomas Quail, Sina Wittmann
wiley +1 more source
Pasta is a transcriptomic aging clock built on an age‐shift learning framework and trained on 17 000 samples across 21 datasets. It accurately predicts relative biological age across tissues, platforms, and species, captures stemness‐to‐senescence transitions, and identifies age‐modulatory perturbations.
Jérôme Salignon +6 more
wiley +1 more source
Geranium: Multimodal Retrieval of Genomics Data Visualizations. [PDF]
Nguyen HN +5 more
europepmc +1 more source
Single‐Atom‐Enhanced Fully Inkjet‐Printed Electrochemical Sensor for Dopamine Detection
Fully inkjet‐printed paper‐based dopamine sensors are fabricated using nitrogen‐doped graphene acid functionalized with copper single atoms. The copper sites uniquely enhance dopamine oxidation through strong molecular adsorption, as verified by electrochemical measurements and DFT calculations. The approach highlights the potential of single‐atom inks
Martin‐Alex Nalepa +11 more
wiley +1 more source
The influence of sense of agency on learning structured regularities: an artificial grammar learning study. [PDF]
Haxhi R, Woźniak M, Wykowska A.
europepmc +1 more source
CLRe: A Synergistic Dual‐Engine Framework for One‐Step Retrosynthesis Prediction
CLRe uses a contrastive difficulty score to order pretrained seq2seq fine‐tuning for retrosynthesis. Reaction embeddings define the ranking score, and a cumulative easy‐to‐hard schedule expands from the easiest subset to the full training set while earlier examples remain active.
Tianhao Su +5 more
wiley +1 more source
Coaching past simple forms of habitual expressions beyond the textbook: A corpus-based experimental investigation. [PDF]
Dagnaw AM, Filatie AY, Adugna ET.
europepmc +1 more source
Differential Tissue‐Coupled Powering for Battery‐Free Injectable Electroceuticals
A thread‐like injectable neural stimulator is powered through differential tissue‐coupled powering (DTCP), which harvests RF‐frequency tissue potentials with an elongated receiver while preserving a injectable cross‐section. The system integrates an ASIC, stimulation electrodes, and a portable transmitter, enabling wireless peripheral nerve stimulation,
Han Wu +13 more
wiley +1 more source
Enhancing oral competence: Evidence-based strategies for developing foreign language speaking skills in Deaf and Hard-of-Hearing (DHH) learners. [PDF]
Olszak I, Borowicz A.
europepmc +1 more source

