Results 111 to 120 of about 9,952 (218)

Importance of SUMOylation Consensus Sequence of MAFK in Regulating EMT, Tumor Growth, Stemness, and Drug Resistance

Cancer Science, EarlyView.
In this study, we focused on SUMOylation, a posttranslational modification, and investigated the importance of its consensus sequence in MAFK. We demonstrated that the non‐SUMOylation mimic mutant MAFK (EA) impairs MAFK‐induced EMT, cellular migration and invasion, tumor and sphere formation, acquisition of stem‐like properties, and drug resistance ...
Thuy Linh Dang Cao, Yukari Okita, Reon Yahatabara, Manar A. Elhinnawi, Nuriza Ulul Azmi, Thanasis Poullikkas, Hozumi Motohashi, Mitsuyasu Kato   +7 more
wiley   +1 more source

In silico exploration of Serratia sp. BRL41 genome for detecting prodigiosin Biosynthetic Gene Cluster (BGC) and in vitro antimicrobial activity assessment of secreted prodigiosin. [PDF]

PLoS One, 2023
Boby F, Bhuiyan MNH, Saha BK, Dey SS, Saha AK, Islam MJ, Bashera MA, Moulick SP, Jahan F, Zaman MAU, Chowdhury SF, Naser SR, Khan MS, Sarkar MMH.   +13 more
europepmc   +1 more source

FKBP5 Mediates Alveolar Fibroblast Necroptosis During Acute Respiratory Distress Syndrome

Cell Proliferation, EarlyView.
Structure diagram of alveolar fibroblast activation in septic ARDS model. FKBP5‐mediated alveolar fibroblast necroptosis, leading to the activation of NF‐κB signalling and the secretion of cytokines and the recruitment of neutrophils, and further orchestrating the inflammatory environment of the alveolar epithelia in septic ARDS.
Dong Zhang, Wei Liu, Ting Sun, Yangyang Xiao, Qiuwen Chen, Xiao Huang, Xiaozhi Wang, Qian Qi, Hao Wang, Tao Wang   +9 more
wiley   +1 more source

PHGDH Orchestrates Cell Cycle Progression to Drive Cardiomyocyte Proliferation and Myocardial Regeneration via TGF‐β/Smad Signalling Pathway

Cell Proliferation, EarlyView.
PHGDH promoted cardiomyocyte proliferation and myocardial regeneration via cell cycle and TGF‐β/Smad signalling pathways during cardiac repair. Moreover, PHGDH benefits cardiac repair and cardiomyocyte proliferation in mammalian mice following MI. ABSTRACT The mature mammalian heart has limited ability for self‐repair and regeneration.
Han Zhang, Li Zhang, Zehao Feng, Xing Li, Zhaohui Qiu, Xingyun Wang, Lingmei Qian   +6 more
wiley   +1 more source

Spaces of mathematical chemistry. [PDF]

Theory Biosci
Restrepo G.
europepmc   +1 more source

Towards origins of virtual artificial life: an overview. [PDF]

Philos Trans R Soc Lond B Biol Sci
Stepney S.
europepmc   +1 more source

Expressive language and social communication abilities in children with spinal muscular atrophy type 1

Developmental Medicine &Child Neurology, EarlyView.
Abstract Aim To investigate parent‐reported expressive language and social communication abilities in children with spinal muscular atrophy type 1 (SMA1) treated with disease‐modifying therapies. Method This was a cross‐sectional feasibility study performed at the Dubowitz Neuromuscular Centre, London (UK), and the Centro Clinico Nemo Pediatrico, Rome (
Chiara Brusa, Bianca Buchignani, Chiara Cutri, Giorgia Coratti, Elaine Clark, Emily Johnson, Nikki Cornell, Mariacristina Scoto, Marika Pane, Eugenio Maria Mercuri, Francesco Muntoni, Giovanni Baranello, The Language and Social Communication in SMA working group, Harriet Weststrate, Emily Barritt, Laura Antonaci, Daniela Leone, Concetta Palermo, Pinki Munot, Adnan Manzur   +19 more
wiley   +1 more source

On the interaction between implicit statistical learning and the alternation advantage: Evidence from manual and oculomotor serial reaction time tasks. [PDF]

PLoS One
Compostella A, Tagliani M, Vender M, Delfitto D.   +3 more
europepmc   +1 more source

Environmental Regulation Using Plasticoding for the Evolution of Robots. [PDF]

Front Robot AI, 2020
Miras K, Ferrante E, Eiben AE.
europepmc   +1 more source

Contested Compromise: Public Policy Reforms as Share Contests

Economics &Politics, EarlyView.
ABSTRACT Public policy reforms often benefit certain societal groups while being costly for others. Both supporters and opponents of reforms can form lobby groups to influence the policy outcome in their preferred direction. This paper presents a simple two‐stage model of a public policy reform that results from the partial implementation of a policy ...
Achim Hagen
wiley   +1 more source