Results 71 to 80 of about 4,451 (294)

NQO1‐Mediated Anoikis Resistance and Immune Evasion Define a High‐Risk Multi‐Omic Subtype for Precision Management of T1 High‐Grade Bladder Cancer

Advanced Science, EarlyView.
Multi‐omic profiling of T1 high‐grade bladder cancer identifies a high‐risk subtype (T1HG1) driven by NQO1, which couples anoikis resistance with immune evasion. NQO1 orchestrates macrophage–T cell crosstalk suppression via CXCL9 modulation. Pharmacological NQO1 inhibition with skullcapflavone II enhances cisplatin efficacy, representing a promising ...
Bin Guo, Chunru Xu, Shufan Fu, Qiang Cheng, Juan Li, Linkuo Shang, Gaojie Li, Yang Yang, Ying Wang, Yanqing Gong, Shengwei Xiong, Jian Fan, Changwei Yuan, Mei Zhang, Yifan Zuo, Elena Papaleo, Yue Shi, Yuan Liang, Xuesong Li, Hongzhao Li, Weimin Ci   +20 more
wiley   +1 more source

Smart Nanotechnologies for Multimodal Neuromodulation and Brain Interfacing

Advanced Science, EarlyView.
Recent advances in smart nanotechnologies are expanding the toolbox for brain interfacing, from wireless neuromodulation and high‐resolution sensing to targeted delivery within the central nervous system. By combining responsive nanomaterials with bioinspired design, these platforms enable multimodal interactions with neurons and glia, while also ...
Tommaso Curiale, Marie Celine Lefevre, Alessio Carmignani, Maria Cristina Ceccarelli, Matteo Battaglini, Attilio Marino, Gianni Ciofani   +6 more
wiley   +1 more source

Equilibrium properties of ionic mixtures - derivation of fluctuation formulas from the grand-canonical ensemble

, 1989
The grand-canonical ensemble is used to derive fluctuation formulae for the particle densities, the pressure and the energy density of a multi-component ionic mixture.
Suttorp, L.G., L. G. Suttorp
core   +1 more source

Integrating Machine Learning With Constant‐Potential Simulation to Unravel Charge‐Transfer Mechanisms in Electrochemical Nitrogen Fixation

Advanced Science, EarlyView.
Integrating interpretable machine learning with the fixed‐potential method reveals a novel mechanism: the catalytic activity of the electrochemical nitrogen reduction reaction is governed by partial charge transfer, induced by variations in the intermediate potential of zero charge under constant potential.
Yufei Xue, Dushuo Feng, Yuefei Zhang, Yang Zhang, Yalong Jiao, Aijun Du, Guoping Gao   +6 more
wiley   +1 more source

Thermodynamic topology and geodesics analysis of accelerated charged-AdS black hole with Barrow entropy corrections

European Physical Journal C: Particles and Fields
The goal of our work is to analyze the thermodynamic topology of accelerated charged anti-de Sitter black holes with a generalized Barrow modification of the entropy.
Muhammad Yasir, Tehreem Aslam, Shahid Qaisar, Wei Liu, Faisal Javed, Mansoor H. Alshehri   +5 more
doaj   +1 more source

Molecular grand-canonical ensemble density functional theory and exploration of chemical space [PDF]

, 2006
We present a rigorous description of chemical space within a molecular grand-canonical ensemble multi-component density functional theory framework. A total energy density functional for chemical compounds in contact with an electron and a proton bath is
Mark E. Tuckerman, von Lilienfeld, O. Anatole, O. Anatole von Lilienfeld, Tuckerman, Mark E.   +3 more
core   +1 more source

Gene regulation in the grand canonical ensemble.

, 2023
a Transcription rate is assumed to be dependent on the configurational state of the genome. When RNA polymerase (RNAP) is bound to the promoter sequence, transcription is initiated with a constant rate equal to the product of k0, the (constant ...
Willem K. Kegel (1495369), Jasper Landman (4232866), Sjoerd M. Verduyn Lunel (17068933)   +2 more
core   +1 more source

Interlayer‐Sliding‐Enabled Multiferroicity and Giant Switchable Anomalous Hall Conductivity in RuO2Zn2F2 Bilayer

Advanced Science, EarlyView.
Interlayer sliding in the RuO2Zn2F2 bilayer induces ferroelectricity and enables reversible valley polarization switching. The electric dipole and valley‐resolved band edges are intimately coupled, revealing sliding ferroelectricity as a powerful mechanism for electrical control of valley degrees of freedom in 2D materials.
Djamel Bezzerga, Imran Khan, Ganie Suhail Ahmad, Jisang Hong   +3 more
wiley   +1 more source

Modulating the Charge Transfer Channels via Constructing Charge‐Assisted Hydrogen‐Bonded Organic Frameworks for Enhanced Photosynthesis of Hydrogen Peroxide

Advanced Science, EarlyView.
This work reports a strategy of engineering charge‐assisted hydrogen bonds to tailor charge transfer channels in HOFs, significantly improving their performance in photocatalytic H2O2 production. ABSTRACT The production of H2O2 via artificial photosynthesis is often limited by inefficient charge‐carrier separation, causing significant charge ...
Yajun Zhao, Xianzhi Lan, Tiantian Chen, Qijie Mo, Chao Peng, Jianbo Jia, Jiewei Liu, Cheng‐Yong Su   +7 more
wiley   +1 more source

Ensembles in M-theory and holography

Journal of High Energy Physics
We discuss that the string/M-theory partition function requires a choice of ensembles, depending on which background fields are held fixed. The background fields correspond to worldvolume couplings in the effective action approach to the superstring ...
Friðrik Freyr Gautason, Jesse van Muiden   +1 more
doaj   +1 more source