Results 131 to 140 of about 210,813 (335)

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

open access: yesFEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid   +3 more
wiley   +1 more source

Status of Supersymmetric Grand Unified Theories [PDF]

open access: green, 1997
B. Ananthanarayan, Peter Minkowski
openalex   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

open access: yesFEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani   +6 more
wiley   +1 more source

Leveraging Artificial Intelligence in Research and Scholarly Work: Innovative Approaches and Practical Applications

open access: yesNew Directions for Adult and Continuing Education, EarlyView.
ABSTRACT This article explores how artificial intelligence (AI) is reshaping scholarly research and writing for faculty in higher education. As AI becomes increasingly integrated into academic workflows, it offers opportunities to enhance efficiency, exchange ideas, and foster creativity, while also raising critical questions about authorship ...
Adam L. McClain, Scott Barton
wiley   +1 more source

Matter antimatter domains: A possible solution to the CP domain wall problem in the early universe [PDF]

open access: yes
An SU(5) grand unified theory model is used to show how the degeneracy between vacua with different spontaneously broken charge parity can be dynamically lifted by a condensate of heavy fermion pairs.
Mohanty, A. K., Stecker, F. W.
core   +1 more source

Altered Dynamic Functional Network Connectivity in Post‐Stroke Aphasia

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Previous studies examining post‐stroke aphasia (PSA) patients via resting‐state functional magnetic resonance imaging (rs‐fMRI) have predominantly focused on static functional connectivity. In contrast, the current investigation aims to elucidate the alterations in dynamic functional network connectivity (dFNC) among PSA patients ...
Guihua Xu   +6 more
wiley   +1 more source

Finite Unification: Theory and Predictions

open access: yesSymmetry, Integrability and Geometry: Methods and Applications, 2010
All-loop Finite Unified Theories (FUTs) are very interesting N=1 supersymmetric Grand Unified Theories (GUTs) which not only realise an old field theoretic dream but also have a remarkable predictive power due to the required reduction of couplings.
Sven Heinemeyer   +2 more
doaj   +1 more source

A grand unifying theory [PDF]

open access: yesJournal of Bodywork and Movement Therapies, 2012
openaire   +2 more sources

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