Results 71 to 80 of about 210,813 (335)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Universally finite gravitational and gauge theories

open access: yesNuclear Physics B, 2015
It is well known that standard gauge theories are renormalizable in D=4 while Einstein gravity is renormalizable in D=2. This is where the research in the field of two derivatives theories is currently standing.
Leonardo Modesto, Lesław Rachwał
doaj   +1 more source

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

open access: yesMolecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian   +10 more
wiley   +1 more source

Supersymmetry from Typicality

open access: yes, 2014
We argue that under a set of simple assumptions the multiverse leads to low energy supersymmetry with the spectrum often called spread or mini-split supersymmetry: the gauginos are in the TeV region with the other superpartners two or three orders of ...
Nomura, Yasunori, Shirai, Satoshi
core   +1 more source

Grand Unified TheorieS

open access: yes, 2019
The author Wan-Chung Hu(born1973) is a MD (National Taiwan University) and PhD (Johns Hopkins University). This book contains theories in physics, chemistry, biology, geosciences, and mathematics. Spinity is a force to drag spacetime to rotate around central mass.
openaire   +2 more sources

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

open access: yesMolecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser   +14 more
wiley   +1 more source

Unitarity constraints on large multiplets of arbitrary gauge groups

open access: yesNuclear Physics B
We impose partial-wave unitarity on 2→2 tree-level scattering processes to derive constraints on the dimensions of large scalar and fermionic multiplets of arbitrary gauge groups.
André Milagre, Luís Lavoura
doaj   +1 more source

Grand Unified Theories without the Desert [PDF]

open access: yesPhysical Review Letters, 2000
We present a Grand Unified Theory (GUT) that has GUT fields with masses of the order of a TeV, but at the same time preserves (at the one-loop level) the success of gauge-coupling unification of the MSSM and the smallness of proton decay operators.
openaire   +3 more sources

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

open access: yesMolecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak   +8 more
wiley   +1 more source

Flavon alignments from orbifolding: SU(5) × SU(3) model with 𝕋6 /∆(54)

open access: yesJournal of High Energy Physics, 2019
We systematically develop the formalism necessary for ensuring that boundary conditions of flavon fields in extra dimensions are consistent with heterotic string theory.
Francisco J. de Anda   +3 more
doaj   +1 more source

Home - About - Disclaimer - Privacy