Results 51 to 60 of about 4,875 (298)

Thinking the Unthinkable: An Alternative Route to a Unified Theory

open access: yesPhilosophies
One of the greatest quests in physics in current times is the search for a grand unified theory—to bring all the forces of nature into one coherent explanatory framework.
Julian Hart
doaj   +1 more source

Relation between proton decay and PMNS phase in the minimal SUSY SO(10) GUT

open access: yesPhysics Letters B, 2017
Proton decay is one of the most important predictions of the grand unified theory (GUT). In the supersymmetric (SUSY) GUT, proton decays via the dimension-five operators need to be suppressed.
Takeshi Fukuyama   +2 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Confronting electroweak fine-tuning with No-Scale Supergravity

open access: yesPhysics Letters B, 2015
Applying No-Scale Supergravity boundary conditions at a heavy unification scale to the Flipped SU(5) grand unified theory with extra TeV-scale vector-like multiplets, i.e.
Tristan Leggett   +4 more
doaj   +1 more source

Muon anomalous magnetic moment and Higgs potential stability in the 331 model from SU(6)

open access: yesEuropean Physical Journal C: Particles and Fields, 2021
We consider a $$SU(3)_c \times SU(3)_L \times U(1)_X$$ S U ( 3 ) c × S U ( 3 ) L × U ( 1 ) X model from a SU(6) Grand Unified Theory (GUT). In order to explain the anomalous magnetic moments of muon and electron, we introduce two new scalar triplets ...
Tianjun Li, Junle Pei, Wenxing Zhang
doaj   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

open access: yesFEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas   +3 more
wiley   +1 more source

Der Traum von der "Grand Unified Theory". Zur Pluralität fachuniversaler Theorien in der Soziologie

open access: yes, 2005
Sutter T. Der Traum von der "Grand Unified Theory". Zur Pluralität fachuniversaler Theorien in der Soziologie. Soziologie.
Sutter, Tilmann
core   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

Constructing 5d orbifold grand unified theories from heterotic strings

open access: yes, 2004
A three-generation Pati–Salam model is constructed by compactifying the heterotic string on a particular T6/Z6 Abelian symmetric orbifold with two discrete Wilson lines. The compactified space is taken to be the Lie algebra lattice G2⊕SU(3)⊕SO(4).
Raby, Stuart   +2 more
core   +1 more source

Ubiquitination of secretory granules promotes their crinophagic degradation in Drosophila

open access: yesFEBS Letters, EarlyView.
Ubiquitination of secretory granules in Drosophila larval salivary glands is a critical molecular trigger for crinophagy, the lysosomal degradation of unreleased, or low‐quality granules. The E3 ubiquitin ligase Cnot4 is recruited to the surface of secretory granules to induce crinophagy.
Tamás Csizmadia   +6 more
wiley   +1 more source

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