Results 41 to 50 of about 119,165 (263)

Remarks on Constitutive Modeling of Granular Materials

open access: yesEng, 2023
In this paper, we provide a brief overview of certain fundamental concepts which can be used to derive constitutive relations for the stress tensor of granular materials. These include concepts such as dilatancy, cohesion, yield criterion, shear banding,
Mehrdad Massoudi
doaj   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

Multiple shear bands in granular materials

open access: yesEPJ Web of Conferences, 2017
The transition regime from quasi-static to dynamic shear regime is studied by discrete element method (DEM) and by means of a mesoscopic model. We show that at moderate shear rate multiple shear bands appear which eventually appear as a continuous shear ...
Lévay Sára, Török János
doaj   +1 more source

Rheology of a confined granular material [PDF]

open access: yesPhysical Review E, 2001
9 pages, 3 .eps figures, submitted to ...
Ovarlez, Guillaume   +2 more
openaire   +4 more sources

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

A Bounding Surface for Granular Materials

open access: yesSoils and Foundations, 1987
ABSTRACT A laboratory investigation has been carried out into initial anisotropy and into the effects of continuous principal stress rotation on the undrained behaviour of two granular materials : a natural angular to sub-angular sand and glass ballotini, which comprises spherical grains.
SHIBUYA, S., HIGHT, D.W.
openaire   +2 more sources

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

open access: yesFEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner   +7 more
wiley   +1 more source

Time-dependent unified hardening model for granular materials

open access: yesYantu gongcheng xuebao, 2019
In recent years, the construction of regional airports in mountainous areas is increasing. The high-fill engineering projects have large fill volume and use local materials, which contain soil, sand, rockfill materials and other geotechnical materials ...
FANG Yu-fei 1, YAO Yang-ping 1, SHU Wen-jun 2
doaj   +1 more source

Spatial and Volumetric Characteristics of Glioblastoma: Associations With Clinical Presentation and Survival

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective We aim to comprehensively analyze how regional tumor and edema characteristics are associated with clinical presentations and survival outcomes in a large cohort of glioblastoma patients. Methods Patients with IDH‐wildtype glioblastoma who received brain MRI from 2010 to 2023 were included.
Daniel J. Zhou   +16 more
wiley   +1 more source

Digital Cognitive Phenotyping for Differential Diagnosis and Monitoring in Neurological Conditions

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To assess the utility, accessibility, and equivalence to supervised scales of online cognitive assessment in older individuals with cognitive impairment. Methods Patients with Alzheimer's disease (AD, n = 31), idiopathic normal pressure hydrocephalus (iNPH, n = 26), and traumatic brain injury (TBI, n = 23) completed online cognitive ...
Martina Del Giovane   +10 more
wiley   +1 more source

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