Results 161 to 170 of about 5,501,717 (307)

Commissural dentate granule cell projections and their rapid formation in the adult brain. [PDF]

PNAS Nexus, 2023
Egger M, Luo W, Cruz-Ochoa N, Lukacsovich D, Varga C, Que L, Maloveczky G, Winterer J, Kaur R, Lukacsovich T, Földy C.   +10 more
europepmc   +1 more source

Fuyuan Huoxue Decoction Promotes Lumbar Interbody Fusion in Rats: Role of Macrophage‐Driven Inflammation and the TLR9/NF‐κB Pathway

Advanced Science, EarlyView.
Fuyuan Huoxue decoction improves lumbar interbody fusion in rats while reducing inflammatory macrophage activity and supporting bone‐forming stem cells. Experiments implicate extracellular DNA and TLR9/NF‐κB signaling in early responses. These findings point to coordinated control of inflammation and osteogenesis as a potential route to stronger spinal
Hongwei Gao, Han Wu, Shaorong Li, Weijian Wang, Yijian Guo, Shuai Cheng, Jiayi Sun, Jilong An, Wei Zhang   +8 more
wiley   +1 more source

Granule Cell Neuronopathy: A Rare Cause of Infectious Ataxia. [PDF]

Mov Disord Clin Pract
Mustafa F, Agarwal A, Garg D, Shah SA, Brijwal M, Soneja M, Garg A, Srivastava AK.   +7 more
europepmc   +1 more source

Synaptic plasticity at the dentate gyrus granule cell to somatostatin-expressing interneuron synapses supports object location memory. [PDF]

Proc Natl Acad Sci U S A, 2023
Grigoryan G, Harada H, Knobloch-Bollmann HS, Kilias A, Kaufhold D, Kulik A, Eyre MD, Bartos M.   +7 more
europepmc   +1 more source

CircFAM65A/CANX Condensates Sequester FAM134B to Inhibit ER‐phagy and Suppress Hepatocellular Carcinoma Progression

Advanced Science, EarlyView.
The novel circRNA circFAM65A suppresses HCC progression. Mechanistically, circFAM65A drives CANX phase separation, which recruits FAM134B into condensates and blocks its interaction with LC3, thereby inhibiting ER‐phagy and HCC progression. Importantly, targeted circFAM65A delivery represents a potential therapeutic strategy for HCC.
Wenxiu Ru, Lunbiao Gan, Yu Lu, Yujing Guo, Qian Huang, Sha Yin, Fengze Nie, Sijia Di, Jiaqi Ning, Siyu Yao, Huanhuan Wan, Le Liu, Zehua Liu, Fa Yang, Weijun Qin, Weihong Wen   +15 more
wiley   +1 more source

Dentate Granule Cell Capacitance Is Stable across the Light/Dark Cycle. [PDF]

eNeuro
Gonzalez JC, Pennock RL, Abdulkareem AF, Luikart BW, Wadiche JI, Overstreet-Wadiche L.   +5 more
europepmc   +1 more source

Adoptive Allogeneic T-Cell Therapy Improves the Clinical Outcome of JC Virus Granule Cell Neuronopathy: A Case Report. [PDF]

Neurol Neuroimmunol Neuroinflamm, 2023
Grote-Levi L, Möhn N, Bonifacius A, Tischer-Zimmermann S, Schweitzer F, Mahmoudi N, Silling S, Warnke C, Maecker-Kolhoff B, Wattjes MP, Eiz-Vesper B, Höglinger GU, Skripuletz T.   +12 more
europepmc   +1 more source

A 4D view on insulin secretory granule turnover in the ß-cell

, 2017
© 2017 John Wiley & Sons Ltd Insulin secretory granule (SG) turnover consists of several highly regulated processes allowing for proper ß-cell function and insulin secretion.
K. Knoch (23483092), Michele Solimena (23481661), H. Mziaut (23483086), A. Müller (52261), M. Neukam (23483089)   +4 more
core  

Reln mRNA Delivery Drives Neurogenic Bone Regeneration by Orchestrating Schwann Cell‐Mediated Exosomal Trafficking

Advanced Science, EarlyView.
MSNs serve as a robust vehicle for CRISPRa‐mediated Reln induction, driving bone repair through the establishment of a neurogenic‐supportive microenvironment. ABSTRACT Neurogenic bone regeneration is essential for the effective restoration of bone tissue functionality, while the mechanisms and new strategies underlying neurogenic bone regeneration ...
Shuai Lin, Qianwen Li, Duo Liu, Mingzhao Li, Han Zhang, Liujing Chen, Yan Yu, Jiuhui Jiang, Chun Xu, Ruili Yang   +9 more
wiley   +1 more source

G-quadruplexes as a source of vulnerability in BRCA2-deficient granule cell progenitors and medulloblastoma. [PDF]

Proc Natl Acad Sci U S A
Keahi DL, Sanders MA, Paul MR, Webster ALH, Fang Y, Wiley TF, Shalaby S, Carroll TS, Chandrasekharappa SC, Sandoval-Garcia C, MacMillan ML, Wagner JE, Hatten ME, Smogorzewska A.   +13 more
europepmc   +1 more source