Results 181 to 190 of about 5,501,717 (307)

KMT2D temporally activates neuronal transcriptional factor genes to mediate cerebellar granule cell differentiation. [PDF]

Sci Adv
Dhar SS, Ko KP, Jang J, Brown-Abel C, Lin T, Awasthi S, Chen K, Sillitoe RV, Park JI, Lee MG.   +9 more
europepmc   +1 more source

p75NTR prevents the onset of cerebellar granule cell migration via RhoA activation. [PDF]

Elife, 2022
Zanin JP, Friedman WJ.
europepmc   +1 more source

PANETH CELL GRANULE OF MOUSE INTESTINE [PDF]

The Journal of Cell Biology, 1962
H M, SELZMAN, R A, LIEBELT
openaire   +2 more sources

A Pooled CRISPR Screen Reveals Genes Critical for Erythroblast Enucleation

American Journal of Hematology, EarlyView.
ABSTRACT Terminal erythroid differentiation involves dramatic cellular remodeling that culminates in the expulsion of the nucleus, a process known as enucleation. While enucleation is conserved across mammals and is crucial for the generation of fully functional erythrocytes, the mechanisms governing this process have remained largely unknown, in part ...
Marilou Tetard, Tianjian Lin, Nana A. Peterson, Rebekah C. Gullberg, Yann Le Guen, Jasmine Moshiri, John G. Doench, Elizabeth S. Egan   +7 more
wiley   +1 more source

Molecular Details of RNA Interactions With FUS Condensates Altering Assembly, Dynamics, and Aggregation

Angewandte Chemie, EarlyView.
Using NMR and molecular simulations, we map how RNA engages FUS LC‐RGG1 within condensates through electrostatic, π‐stacking, and polar contacts. These multivalent RNA contacts help stabilize RNA within FUS condensates while also reshaping condensate composition and dynamics.
Tongyin Zheng, Kandarp A. Sojitra, Samara Cummings, Qizan Chen, Priyesh Mohanty, Jeetain Mittal, Nicolas L. Fawzi   +6 more
wiley   +2 more sources

SMARCA5 is required for the development of granule cell neuron precursors and Sonic Hedgehog Medulloblastoma growth. [PDF]

Sci Rep
Tsiami F, Drwesh L, Surender S, Fitzgerald J, Schittenhelm J, Picketts DJ, Segal RA, Tabatabai G, Merk DJ.   +8 more
europepmc   +1 more source

Tetrodotoxin prevents heat-shock induced granule cell dispersion in hippocampal slice cultures. [PDF]

Front Cell Dev Biol, 2022
Ahrari A, Meseke M, Förster E.
europepmc   +1 more source

Differential Diagnosis of Mucopolysaccharidoses Types I, II, III, IVA, and VI Through Analysis of Leukocytic Inclusions

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Mucopolysaccharidoses (MPS) are lysosomal storage disorders characterized by the accumulation of glycosaminoglycans (GAGs), which can lead to cytoplasmic alterations in leukocytes. The objective of this study was to characterize leukocyte inclusions in patients with different types of MPS and assess their diagnostic relevance.
Márcio A. W. Melo, Marcelo S. Kertenetzky, Cristina M. Silveira, Maíra M. Ribeiro, Paula F. Medeiros, Gabriela S. Arcanjo   +5 more
wiley   +1 more source

The Nature of Cell‐Penetrating Poly(disulfide)s

Angewandte Chemie, EarlyView.
The mode of action of cell‐penetrating poly(disulfide)s (CPDs) is elucidated to understand thiol‐mediated uptake (TMU) in general and guide future efforts to control cellular entry for chemicals delivery and pathogen defense. ABSTRACT Cell‐penetrating poly(disulfide)s (CPDs) are the most popular thiol‐mediated uptake (TMU) tools for delivering attached
Saidbakhrom Saidjalolov, Giacomo Renno, Yuheng Zhang, Michael Cognet, Justin Neuman, Andreas Hennig, Naomi Sakai, Stefan Matile   +7 more
wiley   +2 more sources

The effects of bipolar disorder granule cell hyperexcitability and lithium therapy on pattern separation in a computational model of the dentate gyrus. [PDF]

Transl Psychiatry
Singh S, Khayachi A, Stern S, Trappenberg T, Alda M, Nunes A.   +5 more
europepmc   +1 more source