Results 181 to 190 of about 178,493 (310)

Tsc2 shapes olfactory bulb granule cell molecular and morphological characteristics. [PDF]

Front Mol Neurosci, 2022
Riley VA, Holmberg JC, Sokolov AM, Feliciano DM.   +3 more
europepmc   +1 more source

The KIF6‐RBP Complex Orchestrates mRNA Transport Required for Sperm Flagellar Assembly

Advanced Science, EarlyView.
Two homozygous deleterious KIF6 variants are identified in unrelated men with impaired sperm motility. Mouse models and multi‐omics analyses reveal that KIF6 cooperates with the RNA‐binding proteins FMRP and FXR1 to deliver mRNAs essential for sperm flagellar assembly, linking disrupted mRNA transport to reduced abundance of key structural and ...
Chunbo Xie, Sibing Yi, Xinle Lin, Shen Zhang, Weili Wang, Shimin Yuan, Lanlan Meng, Yong Li, Chen Tan, Chunjia Wei, Yanyan Yu, Yaoqiong Liang, Huan Zhang, Liang Hu, Guangxiu Lu, Wenbin He, Qianjun Zhang, Juan Du, Ge Lin, Chaofeng Tu, Yue‐Qiu Tan   +20 more
wiley   +1 more source

Synaptic Gpr85 Influences Cerebellar-Granule-Cell Electrical Properties and Light-Induced Behavior in Zebrafish. [PDF]

J Neurosci
Darche-Gabinaud R, Kaafarani A, Chazalon M, Suain V, Hendrickx E, Conrard L, Lefort A, Libert F, Demirler MC, Schiffmann SN, Perez-Morga D, Wittamer V, Parmentier M, Pirson I.   +13 more
europepmc   +1 more source

Cerebellum as a kernel machine: A novel perspective on expansion recoding in granule cell layer. [PDF]

Front Comput Neurosci, 2022
Bae H, Park SY, Kim SJ, Kim CE.
europepmc   +1 more source

A Pathology‐Instructed Theranostic Platform with Mechanoadaptive and ROS‐Powered Nanobreathing Functions for Precision Myocardial Repair

Advanced Science, EarlyView.
We developed a pH responsive theranostic serum albumin hydrogel named BST, functionalized with MRI and CT probes and loaded with mitochondria targeted CAT‐SOD nanogels, that rapidly self repairs and mechanically stabilizes the infarcted myocardium, releases therapeutic nanogels and albumin under hypoxia induced acidosis to clear mitochondrial ROS ...
Zheng Luo, Cui Yang, Liuzhou Mao, Panqin Ma, Chiyu Jia, Karen Yuanting Tang, Xian Jun Loh, Yun‐Long Wu   +7 more
wiley   +1 more source

Lamin A/C regulates cerebellar granule cell maturation. [PDF]

Cell Biol Toxicol
Vilardo L, Cifola I, Nardella M, Pelucchi P, Ciotti MT, Bianchi A, Rinaldi A, Arisi I, Brandi R, d'Onofrio M, Galvanetto N, Gatti G, Catalano M, Lanzuolo C, Guglielmi L, D'Agnano I.   +15 more
europepmc   +1 more source

p75NTR prevents the onset of cerebellar granule cell migration via RhoA activation. [PDF]

Elife, 2022
Zanin JP, Friedman WJ.
europepmc   +1 more source

The role of Rab27a in the regulation of melanosome distribution within retinal pigment epithelial cells

, 2004
Melanosomes within the retinal pigment epithelium (RPE) of mammals have long been thought to exhibit no movement in response to light, unlike fish and amphibian RPE.
Seabra, MC, Futter, CE, Ramalho, JS, Jaissle, GB, Seeliger, MW   +4 more
core  

Targeting the ATX‐LPA Axis Overcomes TKI Resistance and Immunosuppression in Renal Cell Carcinoma via Dual Inhibition of AKT/mTOR and TBK1/IRF3 Pathways

Advanced Science, EarlyView.
ABSTRACT Background Therapeutic resistance limits durable survival in advanced/metastatic renal cell carcinoma (RCC) treated with first‐line tyrosine kinase inhibitor (TKI) plus immune checkpoint inhibitor (ICI). We sought to define key resistance drivers and actionable targets.
Jinchen Luo, Hansen Lin, Haoqian Feng, Lei Tan, Xi Liu, Yong Huang, Junjie Cen, Jiajie Chen, Xinwei Zhou, Mingjie Lin, Wuyuan Liao, Zheyu Ai, Minyu Chen, Yinghan Wang, Wei Chen, Junhang Luo, Yanping Liang   +16 more
wiley   +1 more source

KMT2D temporally activates neuronal transcriptional factor genes to mediate cerebellar granule cell differentiation. [PDF]

Sci Adv
Dhar SS, Ko KP, Jang J, Brown-Abel C, Lin T, Awasthi S, Chen K, Sillitoe RV, Park JI, Lee MG.   +9 more
europepmc   +1 more source