Results 1 to 10 of about 170,090 (116)

Perisomatic innervation on the semilunar granule cells and outer molecular layer granule cells of the dentate gyrus of the mouse [PDF]

Frontiers in Neuroanatomy
Semilunar granule cells in the dentate gyrus represent a distinct type of granule cell, distinguished by their unique morphology and physiology. These cells are located within the inner molecular layer and the upper juxta-granule cell layer of the ...
Laura Rovira-Esteban, Isaac Vieco-Martí, Javier Herraiz-Cabanes, Emilio Varea, Juan Nacher, Juan Nacher, Juan Nacher, Carlos Crespo, José Miguel Blasco-Ibáñez   +8 more
doaj   +2 more sources

Structured sampling of molecularly classified mossy fiber inputs by cerebellar granule cells [PDF]

Frontiers in Computational Neuroscience
The cerebellar granule cell layer receives mossy fiber inputs from diverse brain regions, yet the principles governing how individual granule cells sample distinct types of inputs remain poorly understood. Using a volumetric correlated light and electron
Xiaomeng Han, Elif Sevde Meral, Jeff W. Lichtman   +2 more
doaj   +2 more sources

Origins, Development, and Compartmentation of the Granule Cells of the Cerebellum

Frontiers in Neural Circuits, 2021
Granule cells (GCs) are the most numerous cell type in the cerebellum and indeed, in the brain: at least 99% of all cerebellar neurons are granule cells.
G. Giacomo Consalez, Daniel Goldowitz, Filippo Casoni, Richard Hawkes   +3 more
doaj   +3 more sources

Single-cell spatial transcriptomic analysis reveals common and divergent features of developing postnatal granule cerebellar cells and medulloblastoma

BMC Biology, 2021
Background Cerebellar neurogenesis involves the generation of large numbers of cerebellar granule neurons (GNs) throughout development of the cerebellum, a process that involves tight regulation of proliferation and differentiation of granule neuron ...
Wenqin Luo, Guan Ning Lin, Weichen Song, Yu Zhang, Huadong Lai, Man Zhang, Juju Miao, Xiaomu Cheng, Yongjie Wang, Wang Li, Wenxiang Wei, Wei-Qiang Gao, Ru Yang, Jia Wang   +13 more
doaj   +1 more source

Differential Structural Development of Adult-Born Septal Hippocampal Granule Cells in the Thy1-GFP Mouse, Nuclear Size as a New Index of Maturation. [PDF]

PLoS ONE, 2015
Adult neurogenesis is frequently studied in the mouse hippocampus. We examined the morphological development of adult-born, immature granule cells in the suprapyramidal blade of the septal dentate gyrus over the period of 7-77 days after mitosis with ...
Tijana Radic, Omar Al-Qaisi, Tassilo Jungenitz, Marcel Beining, Stephan W Schwarzacher   +4 more
doaj   +1 more source

Global remapping in granule cells and mossy cells of the mouse dentate gyrus

Cell Reports, 2023
Summary: Hippocampal place cells exhibit spatially modulated firing, or place fields, which can remap to encode changes in the environment or other variables.
Sang Hoon Kim, Douglas GoodSmith, Stephanie J. Temme, Fumika Moriya, Guo-li Ming, Kimberly M. Christian, Hongjun Song, James J. Knierim   +7 more
doaj   +1 more source

Short-Term Plasticity in Cortical GABAergic Synapses on Olfactory Bulb Granule Cells Is Modulated by Endocannabinoids

Frontiers in Cellular Neuroscience, 2021
Olfactory bulb and higher processing areas are synaptically interconnected, providing rapid regulation of olfactory bulb circuit dynamics and sensory processing. Short-term plasticity changes at any of these synapses could modulate sensory processing and
Fu-Wen Zhou, Adam C. Puche
doaj   +1 more source

Inability of granule polarization by NK cells defines tumor resistance and can be overcome by CAR or ADCC mediated targeting

Journal for ImmunoTherapy of Cancer, 2021
Background On encountering a susceptible target, natural killer (NK) cells mediate cytotoxicity through highly regulated steps of directed degranulation.
Torsten Tonn, Winfried Wels, Jiri Eitler, Natalie Wotschel, Nicole Miller, Laurent Boissel, Hans G Klingemann   +6 more
doaj   +1 more source

Improved Separation of Odor Responses in Granule Cells of the Olfactory Bulb During Odor Discrimination Learning

Frontiers in Cellular Neuroscience, 2020
In the olfactory bulb, olfactory information is translated into ensemble representations by mitral/tufted cells, and these representations change dynamically in a context-dependent manner.
Dejuan Wang, Yang Chen, Yiling Chen, Xiaowen Li, Penglai Liu, Zhaoyang Yin, Anan Li   +6 more
doaj   +1 more source

Mast cell granule motility and exocytosis is driven by dynamic microtubule formation and kinesin-1 motor function

PLoS ONE, 2022
Mast cells are tissue-resident immune cells that have numerous cytoplasmic granules which contain preformed pro-inflammatory mediators. Upon antigen stimulation, sensitized mast cells undergo profound changes to their morphology and rapidly release ...
Jeremies Ibanga, Eric L. Zhang, Gary Eitzen, Yitian Guo   +3 more
doaj   +2 more sources