Results 11 to 20 of about 259,502 (294)

Granule Cells in the CA3 Area [PDF]

open access: yesJournal of Neuroscience, 2010
A fundamental property of neuronal networks in Ammon's horn is that each area comprises a single glutamatergic cell population and various types of GABAergic neurons. Here we describe an exception to this rule, in the form of granule cells that reside within the CA3 area and function as glutamatergic nonprincipal cells with distinct properties.
János, Szabadics   +4 more
openaire   +2 more sources

Mast cell granule motility and exocytosis is driven by dynamic microtubule formation and kinesin-1 motor function

open access: yesPLoS ONE, 2022
Mast cells are tissue-resident immune cells that have numerous cytoplasmic granules which contain preformed pro-inflammatory mediators. Upon antigen stimulation, sensitized mast cells undergo profound changes to their morphology and rapidly release ...
Jeremies Ibanga   +3 more
doaj   +2 more sources

Improved Separation of Odor Responses in Granule Cells of the Olfactory Bulb During Odor Discrimination Learning

open access: yesFrontiers in Cellular Neuroscience, 2020
In the olfactory bulb, olfactory information is translated into ensemble representations by mitral/tufted cells, and these representations change dynamically in a context-dependent manner.
Dejuan Wang   +6 more
doaj   +1 more source

RNA Granules in Germ Cells [PDF]

open access: yesCold Spring Harbor Perspectives in Biology, 2011
"Germ granules" are cytoplasmic, nonmembrane-bound organelles unique to germline. Germ granules share components with the P bodies and stress granules of somatic cells, but also contain proteins and RNAs uniquely required for germ cell development. In this review, we focus on recent advances in our understanding of germ granule assembly, dynamics, and ...
Ekaterina, Voronina   +3 more
openaire   +2 more sources

Axonal sodium channel NaV1.2 drives granule cell dendritic GABA release and rapid odor discrimination. [PDF]

open access: yesPLoS Biology, 2018
Dendrodendritic synaptic interactions between olfactory bulb mitral and granule cells represent a key neuronal mechanism of odor discrimination. Dendritic release of gamma-aminobutyric acid (GABA) from granule cells contributes to stimulus-dependent ...
Daniel Nunes, Thomas Kuner
doaj   +1 more source

Enhanced Non-Associative Long-Term Potentiation in Immature Granule Cells in the Dentate Gyrus of Adult Rats

open access: yesFrontiers in Synaptic Neuroscience, 2022
The dentate gyrus is one of the few sites of neurogenesis in the adult brain. Integration of new-generated granule cells into the hippocampal circuitry provides a substrate for structural plasticity, fundamental for normal function of adult hippocampus ...
Natalia A. Simonova   +3 more
doaj   +1 more source

Population-scale organization of cerebellar granule neuron signaling during a visuomotor behavior. [PDF]

open access: yes, 2017
Granule cells at the input layer of the cerebellum comprise over half the neurons in the human brain and are thought to be critical for learning. However, little is known about granule neuron signaling at the population scale during behavior.
Aksay, Emre RF   +5 more
core   +2 more sources

Expression of the AMPA receptor subunits GluR1 and GluR2 is associated with granule cell maturation in the dentate gyrus

open access: yesFrontiers in Neuroscience, 2011
The dentate gyrus produces new granule neurons throughout adulthood in mammals from rodents to humans. During granule cell maturation, defined markers are expressed in a highly regulated sequential process, which is necessary for directed neuronal ...
Hideo eHagihara   +9 more
doaj   +1 more source

A Sparse, Spatially Biased Subtype of Mature Granule Cell Dominates Recruitment in Hippocampal-Associated Behaviors

open access: yesCell Reports, 2020
Summary: Animals can store information about experiences by activating specific neuronal populations, and subsequent reactivation of these neural ensembles can lead to recall of salient experiences.
Sarah R. Erwin   +5 more
doaj   +1 more source

Drug-induced stress granule formation protects sensory hair cells in mouse cochlear explants during ototoxicity [PDF]

open access: yes, 2019
Stress granules regulate RNA translation during cellular stress, a mechanism that is generally presumed to be protective, since stress granule dysregulation caused by mutation or ageing is associated with neurodegenerative disease.
Dawson, Sally J.   +6 more
core   +2 more sources

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