Results 11 to 20 of about 4,987,565 (306)
Granule Cell Dispersion in Human Temporal Lobe Epilepsy: Proteomics Investigation of Neurodevelopmental Migratory Pathways [PDF]
Frontiers in Cellular Neuroscience, 2020 Granule cell dispersion (GCD) is a common pathological feature observed in the hippocampus of patients with Mesial Temporal Lobe Epilepsy (MTLE). Pathomechanisms underlying GCD remain to be elucidated, but one hypothesis proposes aberrant reactivation of
Joan Y. W. Liu +9 more
doaj +2 more sources
Granule Cells in the CA3 Area [PDF]
Journal of Neuroscience, 2010 A fundamental property of neuronal networks in Ammon's horn is that each area comprises a single glutamatergic cell population and various types of GABAergic neurons. Here we describe an exception to this rule, in the form of granule cells that reside within the CA3 area and function as glutamatergic nonprincipal cells with distinct properties.
János, Szabadics +4 more
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RNA Granules in Germ Cells [PDF]
Cold Spring Harbor Perspectives in Biology, 2011 "Germ granules" are cytoplasmic, nonmembrane-bound organelles unique to germline. Germ granules share components with the P bodies and stress granules of somatic cells, but also contain proteins and RNAs uniquely required for germ cell development. In this review, we focus on recent advances in our understanding of germ granule assembly, dynamics, and ...
Ekaterina, Voronina +3 more
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Characterization of granule-like structures in non-endocrine cells [PDF]
, 2006 All eukaryotic cells have transport pathways to constitutively secrete proteins. Endocrine, neuroendocrine, and exocrine cells in addition have a regulated secretory pathway that serves the controlled release of hormones, neuropeptides or digestive ...
Stettler, Hansruedi
core +1 more source
Bidirectional GABAergic control of AP firing in newly-generated young granule cells of the adult hippocampus [PDF]
, 2015 Gamma-aminobutyric acid (GABA) is the first transmitter which provides synaptic input to newly generated neurons. In the first 2-3 weeks after mitosis, young neurons show an elevated intracellular chloride concentration due to the expression of the NKCC1
Heigele, Stefanie
core +1 more source
Frontiers in Neuroscience, 2011 The dentate gyrus produces new granule neurons throughout adulthood in mammals from rodents to humans. During granule cell maturation, defined markers are expressed in a highly regulated sequential process, which is necessary for directed neuronal ...
Hideo eHagihara +9 more
doaj +1 more source
Axonal sodium channel NaV1.2 drives granule cell dendritic GABA release and rapid odor discrimination. [PDF]
PLoS Biology, 2018 Dendrodendritic synaptic interactions between olfactory bulb mitral and granule cells represent a key neuronal mechanism of odor discrimination. Dendritic release of gamma-aminobutyric acid (GABA) from granule cells contributes to stimulus-dependent ...
Daniel Nunes, Thomas Kuner
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Granule Leakage Induces Cell-Intrinsic, Granzyme B-Mediated Apoptosis in Mast Cells. [PDF]
, 2021 Mast cells are multifunctional immune cells scattered in tissues near blood vessels and mucosal surfaces where they mediate important reactions against parasites and contribute to the pathogenesis of allergic reactions.
Burgener, Sabrina Sofia +15 more
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Expression of tryptophan 2,3-dioxygenase in mature granule cells of the adult mouse dentate gyrus
Molecular Brain, 2010 New granule cells are continuously generated in the dentate gyrus of the adult hippocampus. During granule cell maturation, the mechanisms that differentiate new cells not only describe the degree of cell differentiation, but also crucially regulate the ...
Ohira, Koji +7 more
doaj +1 more source
Cell Reports, 2020 Summary: Animals can store information about experiences by activating specific neuronal populations, and subsequent reactivation of these neural ensembles can lead to recall of salient experiences.
Sarah R. Erwin +5 more
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