Results 31 to 40 of about 4,987,565 (306)

Rab3D is critical for secretory granule maturation in PC12 cells. [PDF]

, 2013
Neuropeptide- and hormone-containing secretory granules (SGs) are synthesized at the trans-Golgi network (TGN) as immature secretory granules (ISGs) and complete their maturation in the F-actin-rich cell cortex.
Sharon A. Tooze (391543), Kögel Tanja, Copier, J., Hodneland, E, Gerdes, HH, Gerdes Hans-Hermann, Tooze, S. A., Tooze Sharon A., Copier, J, Rüdiger Rudolf (151449), Tanja Kögel, Romano Regazzi, Rudolf Rüdiger, Copier John, Gerdes, H. H., Tooze, SA, Tanja Kögel (391540), Kögel, T., Hans-Hermann Gerdes, Kögel, T, Hodneland Erlend, John Copier, Tooze, S.A., Rudolf, R., Regazzi Romano, Regazzi, R, Erlend Hodneland, Gerdes, H.H., Erlend Hodneland (391541), Regazzi, R., Sharon A Tooze, Hodneland, E., John Copier (391542), Rudolf, R, Romano Regazzi (210061), Rüdiger Rudolf, Hans-Hermann Gerdes (127873), Rudolf, Rüdiger, Kögel, Tanja, Regazzi, Romano, Hodneland, Erlend, Copier, John, Gerdes, Hans-Hermann, Tooze, Sharon A.   +43 more
core   +1 more source

Granule Cells analysis (LiveDoc)

, 2023
Collection of LiveDocs from project A03 of the SFB 1456, which replicates findings on the publication "3d virtual histology reveals pathological alterations of cerebellar granule cells in Multiple Sclerosis" (DOI)
Jakob Frost, Mareike Töpperwien, Müller, Jan-Hendrik, Bernhard Schmitzer, Jan-Hendrik Müller, Jonas Franz, Frost, Jakob, Töpperwien, Mareike, Eckermann, Marina, Schmitzer, Bernhard, Franz, Jonas, Marina Eckermann   +11 more
core   +1 more source

Biosensor measurement of purine release from cerebellar cultures and slices [PDF]

, 2010
We have previously described an action-potential and Ca2+-dependent form of adenosine release in the molecular layer of cerebellar slices. The most likely source of the adenosine is the parallel fibres, the axons of granule cells. Using microelectrode
Eason, Robert, Robert Eason, Dale, Nicholas, Wall, Mark J., Mark Wall, Nicholas Dale   +5 more
core   +1 more source

Generation and characterization of an Nse-CreERT2 transgenic line suitable for inducible gene manipulation in cerebellar granule cells. [PDF]

PLoS ONE, 2014
We created an Nse-CreERT2 mouse line expressing the tamoxifen-inducible CreERT2 recombinase under the control of the neuron-specific enolase (Nse) promoter.
Theresa Pohlkamp, Laura Steller, Petra May, Thomas Günther, Roland Schüle, Michael Frotscher, Joachim Herz, Hans H Bock   +7 more
doaj   +1 more source

The distribution of N-acetylgalactosamine in the cochlear nucleus of the gerbil revealed by lectin binding with soybean agglutinin [PDF]

, 1994
A horseradish peroxidase conjugated lectin from Glycine max (soy bean agglutinin; SBA) was used to characterise the distribution of N-acetylgalactosamine in the cochlear nucleus of the mongolian gerbil. SBA bound differentially to a variety of structures
Gleich, Otto, Otto Gleich
core   +1 more source

PTEN deletion increases hippocampal granule cell excitability in male and female mice

Neurobiology of Disease, 2017
Deletion of the mTOR pathway inhibitor PTEN from postnatally-generated hippocampal dentate granule cells causes epilepsy. Here, we conducted field potential, whole cell recording and single cell morphology studies to begin to elucidate the mechanisms by ...
Victor R. Santos, Raymund Y.K. Pun, Salwa R. Arafa, Candi L. LaSarge, Shane Rowley, Shadi Khademi, Tom Bouley, Katherine D. Holland, Norberto Garcia-Cairasco, Steve C. Danzer   +9 more
doaj   +1 more source

Mitral cell spike synchrony modulated by dendrodendritic synapse location

Frontiers in Computational Neuroscience, 2012
On their long lateral dendrites, mitral cells of the olfactory bulb form dendrodendritic synapses with large populations of granule cell interneurons. The mitral-granule cell microcircuit operating through these reciprocal synapses has been implicated in
Thomas S McTavish, Michele eMigliore, Gordon M Shepherd, Michael L. Hines   +3 more
doaj   +1 more source

Cerebellar granule cells are predominantly generated by terminal symmetric divisions of granule cell precursors [PDF]

Developmental Dynamics, 2015
Background: Neurons in the central nervous system (CNS) are generated by symmetric and asymmetric cell division of neural stem cells and their derivative progenitor cells. Cerebellar granule cells are the most abundant neurons in the CNS, and are generated by intensive cell division of granule cell precursors (GCPs) during postnatal development ...
Kie, Nakashima, Hiroki, Umeshima, Mineko, Kengaku   +2 more
openaire   +2 more sources

Golgi cell-mediated activation of postsynaptic GABA(B) receptors induces disinhibition of the Golgi cell-granule cell synapse in rat cerebellum. [PDF]

PLoS ONE, 2012
In the cerebellar glomerulus, GABAergic synapses formed by Golgi cells regulate excitatory transmission from mossy fibers to granule cells through feed-forward and feedback mechanisms.
Federico Brandalise, Urs Gerber, Paola Rossi   +2 more
doaj   +1 more source

Multimodal sensory integration in single cerebellar granule cells in vivo

eLife, 2015
The mammalian cerebellum is a highly multimodal structure, receiving inputs from multiple sensory modalities and integrating them during complex sensorimotor coordination tasks.
Taro Ishikawa, Misa Shimuta, Michael Häusser   +2 more
doaj   +1 more source