Axonal sodium channel NaV1.2 drives granule cell dendritic GABA release and rapid odor discrimination. [PDF]
PLoS Biology, 2018 Dendrodendritic synaptic interactions between olfactory bulb mitral and granule cells represent a key neuronal mechanism of odor discrimination. Dendritic release of gamma-aminobutyric acid (GABA) from granule cells contributes to stimulus-dependent ...
Daniel Nunes, Thomas Kuner
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Hilar mossy cell circuitry controlling dentate granule cell excitability
Frontiers in Neural Circuits, 2013 Glutamatergic hilar mossy cells of the dentate gyrus can either excite or inhibit distant granule cells, depending on whether their direct excitatory projections to granule cells or their projections to local inhibitory interneurons dominate. However, it
Seiichiro eJinde +2 more
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Frontiers in Cellular Neuroscience, 2015 To understand the potential role of enhanced hippocampal neurogenesis after pilocarpine-induced status epilepticus (SE) in the development of epilepsy, we quantitatively analyzed the geometry of apical dendrites, synaptic transmission, and activation ...
Fei eGao +6 more
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Enzymes of the Mast Cell Granule
Journal of Investigative Dermatology, 1980 Rat mast cell granules contain a spectrum of enzymes as established by histochemical techniques and subcellular fractionation. However, 35% of the beta-glucuronidase, 30% of the beta-D-galactosidase, 14% of the beta-hexosaminidase and all of the acid phosphatase is not available for immunologic release from purified rat serosal mast cells, suggesting ...
Schwartz, Lawrence B., Frank Austen, K.
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Differentiated cytoplasmic granule formation in quiescent and non-quiescent cells upon chronological aging [PDF]
, 2016 Stationary phase cultures represent a complicated cell population comprising at least two different cell types, quiescent (Q) and non-quiescent (NQ) cells. Q and NQ cells have different lifespans and cell physiologies.
Kuo-Yu Cheng +3 more
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GABA-Independent GABAA Receptor Openings Maintain Tonic Currents [PDF]
, 2013 Activation of GABAA receptors (GABAARs) produces two forms of inhibition: ‘phasic’ inhibition generated by the rapid, transient activation of synaptic GABAARs by presynaptic GABA release, and tonic inhibition generated by the persistent activation of ...
Herd, Murray B +27 more
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Cultured subventricular zone progenitor cells transduced with neurogenin-2 become mature glutamatergic neurons and integrate into the dentate gyrus. [PDF]
, 2012 We have previously shown that transplantation of immature DCX+/NeuN+/Prox1+ neurons (found in the neonatal DG), but not undifferentiated neuronal progenitor cells (NPCs) from ventral subventricular zone (SVZ), results in neuronal maturation in vivo ...
Xia Chen +19 more
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Specification of Granule Cells and Purkinje Cells.
, 2021 Granule cells and Purkinje cells are the major populations of neurons in the cerebellum. Their specification depends on a combination of regional identity and spatiotemporal cues.
Rook, Victoria +4 more
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Biosensor measurement of purine release from cerebellar cultures and slices [PDF]
, 2010 We have previously described an action-potential and Ca2+-dependent form of adenosine release in the molecular layer of cerebellar slices. The most likely source of the adenosine is the parallel fibres, the axons of granule cells. Using microelectrode
Eason, Robert +5 more
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Generation and characterization of an Nse-CreERT2 transgenic line suitable for inducible gene manipulation in cerebellar granule cells. [PDF]
PLoS ONE, 2014 We created an Nse-CreERT2 mouse line expressing the tamoxifen-inducible CreERT2 recombinase under the control of the neuron-specific enolase (Nse) promoter.
Theresa Pohlkamp +7 more
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