Results 21 to 30 of about 4,987,565 (306)

Enhanced Non-Associative Long-Term Potentiation in Immature Granule Cells in the Dentate Gyrus of Adult Rats

Frontiers in Synaptic Neuroscience, 2022
The dentate gyrus is one of the few sites of neurogenesis in the adult brain. Integration of new-generated granule cells into the hippocampal circuitry provides a substrate for structural plasticity, fundamental for normal function of adult hippocampus ...
Natalia A. Simonova, Maxim A. Volgushev, Maxim A. Volgushev, Alexey Y. Malyshev   +3 more
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Functional and structural properties of dentate granule cells with hilar basal dendrites in mouse entorhino-hippocampal slice cultures [PDF]

, 2012
During postnatal development hippocampal dentate granule cells (GCs) often extend dendrites from the basal pole of their cell bodies into the hilar region. These so-called hilar basal dendrites (hBD) usually regress with maturation.
Gerlind Schuldt, Zahn, Nadine, Maggio, Nicola, Willems, Laurent Maximilian, Nicola Maggio, Thomas Deller, Vnenčák, Matej, Denise Becker, Jedlička, Peter, Matej Vnencak, Schuldt, Gerlind, Nadine Zahn, Vlachos, Andreas, Peter Jedlicka, Andreas Vlachos, Becker, Denise, Deller, Thomas, Laurent Maximilian Willems, Becker Denise, Jedlicka Peter, Willems Laurent Maximilian, Deller Thomas, Vnencak Matej, Zahn Nadine, Schuldt Gerlind, Vlachos Andreas, Maggio Nicola   +26 more
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Entorhinal denervation induces homeostatic synaptic scaling of excitatory postsynapses of dentate granule cells in mouse organotypic slice cultures [PDF]

, 2012
Denervation-induced changes in excitatory synaptic strength were studied following entorhinal deafferentation of hippocampal granule cells in mature (≥3 weeks old) mouse organotypic entorhino-hippocampal slice cultures.
Roeper, Jochen, Roeper Jochen, Winkels, Raphael, Denise Becker (179935), Thomas Deller, Thomas Deller (179947), Denise Becker, Jedlička, Peter, Becker Denise, Jochen Roeper, Jedlicka Peter, Winkels Raphael, Andreas Vlachos (47497), Vlachos Andreas, Vlachos, Andreas, Andreas Vlachos, Peter Jedlicka, Jochen Roeper (179944), Becker, Denise, Peter Jedlicka (179938), Raphael Winkels (179941), Deller Thomas, Deller, Thomas, Raphael Winkels   +23 more
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Hilar mossy cell circuitry controlling dentate granule cell excitability

Frontiers in Neural Circuits, 2013
Glutamatergic hilar mossy cells of the dentate gyrus can either excite or inhibit distant granule cells, depending on whether their direct excitatory projections to granule cells or their projections to local inhibitory interneurons dominate. However, it
Seiichiro eJinde, Veronika eZsiros, Kazu eNakazawa   +2 more
doaj   +1 more source

GABA-Independent GABAA Receptor Openings Maintain Tonic Currents [PDF]

, 2013
Activation of GABAA receptors (GABAARs) produces two forms of inhibition: ‘phasic’ inhibition generated by the rapid, transient activation of synaptic GABAARs by presynaptic GABA release, and tonic inhibition generated by the persistent activation of ...
Herd, Murray B, Belelli, D., Wlodarczyk, A. I., Sylantyev, S., Linthorst, Astrid C.E., Walker, Matthew C., Walker, M. C., Rusakov, Dmitri A, Lambert, Jeremy J, Wlodarczyk, Agnieszka I., Kersanté, Flavie, Walker, Matthew C, Semyanov, A., Semyanov, Alexey, Rusakov, Dmitri A., Rusakov, D. A., Herd, Murray B., Linthorst, A. C. E., Lambert, Jeremy J., Pavlov, I., Linthorst, Astrid C E, Lambert, J. J., Herd, M. B., Kersante, F., Wlodarczyk, Agnieszka I, Pavlov, Ivan, Sylantyev, Sergiy, Belelli, Delia   +27 more
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Specification of Granule Cells and Purkinje Cells.

, 2021
Granule cells and Purkinje cells are the major populations of neurons in the cerebellum. Their specification depends on a combination of regional identity and spatiotemporal cues.
Rook, Victoria, Wilson, Leigh, Varela, Tristan, Butts, Thomas, Wingate, Richard   +4 more
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Dendritic morphology, synaptic transmission, and activity of mature granule cells born following pilocarpine-induced status epilepticus in the rat

Frontiers in Cellular Neuroscience, 2015
To understand the potential role of enhanced hippocampal neurogenesis after pilocarpine-induced status epilepticus (SE) in the development of epilepsy, we quantitatively analyzed the geometry of apical dendrites, synaptic transmission, and activation ...
Fei eGao, Xueying eSong, Dexiao eZhu, Xiaochen eWang, Aijun eHao, Victor J. Nadler, Ren-Zhi eZhan   +6 more
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Enzymes of the Mast Cell Granule

Journal of Investigative Dermatology, 1980
Rat mast cell granules contain a spectrum of enzymes as established by histochemical techniques and subcellular fractionation. However, 35% of the beta-glucuronidase, 30% of the beta-D-galactosidase, 14% of the beta-hexosaminidase and all of the acid phosphatase is not available for immunologic release from purified rat serosal mast cells, suggesting ...
Schwartz, Lawrence B., Frank Austen, K.
openaire   +2 more sources

Differentiated cytoplasmic granule formation in quiescent and non-quiescent cells upon chronological aging [PDF]

, 2016
Stationary phase cultures represent a complicated cell population comprising at least two different cell types, quiescent (Q) and non-quiescent (NQ) cells. Q and NQ cells have different lifespans and cell physiologies.
Kuo-Yu Cheng, Jung-Chi Chao, Jun-Yi Leu, Hsin-Yi Lee   +3 more
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Disrupted hippocampal network physiology following PTEN deletion from newborn dentate granule cells

Neurobiology of Disease, 2016
Abnormal hippocampal granule cells are present in patients with temporal lobe epilepsy, and are a prominent feature of most animal models of the disease. These abnormal cells are hypothesized to contribute to epileptogenesis.
Candi L. LaSarge, Raymund Y.K. Pun, Michael B. Muntifering, Steve C. Danzer   +3 more
doaj   +1 more source