Results 1 to 10 of about 62,294 (261)
Cytoplasmic RNA Granules and Viral Infection [PDF]
Annual Review of Virology, 2014 RNA granules are dynamic cellular structures essential for proper gene expression and homeostasis. The two principal types of cytoplasmic RNA granules are stress granules, which contain stalled translation initiation complexes, and processing bodies (P bodies), which concentrate factors involved in mRNA degradation.
Richard E Lloyd
exaly +3 more sources
Single mRNP Analysis Reveals that Small Cytoplasmic mRNP Granules Represent mRNA Singletons
Cell Reports, 2019 Summary: Small cytoplasmic mRNP granules are implicated in mRNA transport, translational control, and decay. Using super-resolution microscopy and fluorescence correlation spectroscopy, we analyzed the molecular composition and dynamics of single ...
Angels Mateu-Regué +2 more
exaly +3 more sources
Multiple Poliovirus Proteins Repress Cytoplasmic RNA Granules [PDF]
Viruses, 2015 We have previously shown that poliovirus (PV) infection induces stress granule (SG) formation early in infection and then inhibits the formation of SG and disperses processing bodies (PBs) by the mid-phase of infection.
Jonathan D. Dougherty +2 more
doaj +3 more sources
PARP1 Activation Controls Stress Granule Assembly after Oxidative Stress and DNA Damage
Cells, 2022 DNA damage causes PARP1 activation in the nucleus to set up the machinery responsible for the DNA damage response. Here, we report that, in contrast to cytoplasmic PARPs, the synthesis of poly(ADP-ribose) by PARP1 opposes the formation of cytoplasmic ...
Anastasia S. Singatulina +5 more
doaj +1 more source
Ultrastructural study on the granulocytes of Uttara fowl (Gallus domesticus) [PDF]
Veterinary World, 2016 Aim: The present study was conducted to know the ultrastructural detail of the blood cells of Uttara fowl (native fowl of Uttarakhand). Materials and Methods: The experiment was conducted on 10 apparently healthy adult birds of either sex reared at the ...
Khan Idrees Mohd +3 more
doaj +1 more source
Cytoplasmic mRNP granules at a glance [PDF]
Journal of Cell Science, 2011 From their transcriptional birth to their degradation, cellular mRNAs are coated with proteins in messenger ribonucleoprotein (mRNP) complexes. The mRNP composition controls every aspect of the life of the mRNA, from pre-mRNA processing to mRNA localization, translation and turnover ...
Stacy L, Erickson, Jens, Lykke-Andersen
openaire +2 more sources
Aspergillus oryzae AoSO is a novel component of stress granules upon heat stress in filamentous fungi. [PDF]
PLoS ONE, 2013 Stress granules are a type of cytoplasmic messenger ribonucleoprotein (mRNP) granule formed in response to the inhibition of translation initiation, which typically occurs when cells are exposed to stress.
Hsiang-Ting Huang +2 more
doaj +1 more source
Cytoplasmic RNA Granules in Somatic Maintenance [PDF]
Gerontology, 2018 Cytoplasmic RNA granules represent subcellular compartments that are enriched in protein-bound RNA species. RNA granules are produced by evolutionary divergent eukaryotes, including yeast, mammals, and plants. The functions of cytoplasmic RNA granules differ widely. They are dictated by the cell type and physiological state, which in turn is determined
Ossama Moujaber, Ursula Stochaj
openaire +2 more sources
UVC-induced stress granules in mammalian cells. [PDF]
PLoS ONE, 2014 Stress granules (SGs) are well characterized cytoplasmic RNA bodies that form under various stress conditions. We have observed that exposure of mammalian cells in culture to low doses of UVC induces the formation of discrete cytoplasmic RNA granules ...
Mohamed Taha Moutaoufik +7 more
doaj +1 more source
Journal of Family Medicine and Primary Care, 2023 Background: This is an observational study which aims to research morphological changes of white blood cells in patients with Systemic Inflammatory Response Syndrome (SIRS) with and without sepsis and evaluate morphological changes in white blood cells ...
Siddharth Sharma +4 more
doaj +1 more source