Malonate induces the assembly of cytoplasmic stress granules [PDF]
FEBS Letters, 2016 Malonate, a classic inhibitor of respiratory electron transport chain, induces mitochondrial stress. Stress granules (SGs) are a kind of dynamic foci structure during stress. The study on the connection of mitochondrial stress and SG assembly is still limited.
Xue, Fu +10 more
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Isolation of Cytoplasmic Pituitary Granules with Gonadotropic Activity [PDF]
The Journal of Cell Biology, 1960 A fraction isolated from the anterior pituitary glands of rats castrate for 8 weeks contained essentially a single cytoplasmic constituent with which the major portion of the gonadotropic hormone activity was associated. The glands were homogenized in an 0.25 M sucrose + 7.3 per cent polyvinylpyrrolidone (PVP) solution and fractionated by differential ...
M W, HARTLEY, W H, McSHAN, H, RIS
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Recruitment of mRNAs to P granules by condensation with intrinsically-disordered proteins
eLife, 2020 RNA granules are protein/RNA condensates. How specific mRNAs are recruited to cytoplasmic RNA granules is not known. Here, we characterize the transcriptome and assembly of P granules, RNA granules in the C. elegans germ plasm.
Chih-Yung S Lee +5 more
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Molecular Aspects of Secretory Granule Exocytosis by Neurons and Endocrine Cells [PDF]
, 1994 Neuronal communication and endocrine signaling are fundamental for integrating the function of tissues and cells in the body. Hormones released by endocrine cells are transported to the target cells through the circulation.
Ahnert-Hilger G. +28 more
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VCP-dependent muscle degeneration is linked to defects in a dynamic tubular lysosomal network in vivo. [PDF]
, 2015 Lysosomes are classically viewed as vesicular structures to which cargos are delivered for degradation. Here, we identify a network of dynamic, tubular lysosomes that extends throughout Drosophila muscle, in vivo. Live imaging reveals that autophagosomes
Davis, Graeme W +4 more
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Formation of Antiviral Cytoplasmic Granules during Orthopoxvirus Infection [PDF]
Journal of Virology, 2011 ABSTRACT Vaccinia virus (VV) mutants lacking the double-stranded RNA (dsRNA)-binding E3L protein (Δ E3L mutant VV) show restricted replication in most cell types, as dsRNA produced by VV activates protein kinase R (PKR), leading to eIF2α phosphorylation and impaired translation initiation.
M, Simpson-Holley +6 more
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BMC Cell Biology, 2010 Background Gene expression is achieved by the coordinated action of multiple factors to ensure a perfect synchrony from chromatin epigenetic regulation through to mRNA export.
Llopis Ana +5 more
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Nuclear import of UBL-domain protein Mdy2 is required for heat-induced stress response in Saccharomyces cerevisiae. [PDF]
PLoS ONE, 2012 Ubiquitin (Ub) and ubiquitin-like (UBL) proteins regulate a diverse array of cellular pathways through covalent as well as non-covalent interactions with target proteins.
Khalid Arhzaouy, Massoud Ramezani-Rad
doaj +1 more source
Stability and performance of two GSBR operated in alternating anoxic/aerobic or anaerobic/aerobic conditions for nutrient removal [PDF]
, 2012 Two granular sludge sequencing batch reactors (GSBR) with alternating anoxic/aerobic (R1) and anaerobic/aerobic (R2) conditions were operated with a 4-carbon-source synthetic influent. The physical properties of the granular sludge were very good (SVI≈20
Bessiere, Yolaine +5 more
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Myo-granules Connect Physiology and Pathophysiology
Journal of Experimental Neuroscience, 2019 A hallmark of many neuromuscular diseases including Alzheimer disease, inclusion body myositis, amyotrophic lateral sclerosis, frontotemporal lobar dementia, and ocular pharyngeal muscular dystrophy is large cytoplasmic aggregates containing the RNA ...
Alicia A Cutler +4 more
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