Results 41 to 50 of about 272,495 (294)
Nuclear import of UBL-domain protein Mdy2 is required for heat-induced stress response in Saccharomyces cerevisiae. [PDF]
PLoS ONE, 2012 Ubiquitin (Ub) and ubiquitin-like (UBL) proteins regulate a diverse array of cellular pathways through covalent as well as non-covalent interactions with target proteins.
Khalid Arhzaouy, Massoud Ramezani-Rad
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Nature Communications, 2017 Sequestering mRNA in cytoplasmic stress granules is a mechanism for translational repression. Here the authors find that p53 mRNA, present in stress granules in activated B lymphocytes, is released upon DNA damage and is translated in a CAP-independent ...
Manuel D. Díaz-Muñoz +5 more
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Stress granules regulate paraspeckles: RNP granule continuum at work
Cell Stress, 2019 Eukaryotic cells contain several types of RNA-protein membraneless macro-complexes – ribonucleoprotein (RNP) granules that form by liquid-liquid phase separation.
Haiyan An, Tatyana A. Shelkovnikova
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The Role of the Z-DNA Binding Domain in Innate Immunity and Stress Granules
Frontiers in Immunology, 2021 Both DNA and RNA can maintain left-handed double helical Z-conformation under physiological condition, but only when stabilized by Z-DNA binding domain (ZDBD).
De Chen Chiang +4 more
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C. elegans germ granules sculpt both germline and somatic RNAome
Nature Communications, 2023 Germ granules are membrane-less organelles essential for small RNA biogenesis and germline development. Among the conserved properties of germ granules is their association with the nuclear membrane. Recent studies demonstrated that LOTUS domain proteins,
Ian F. Price +4 more
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Prion‐Like Protein LENG8‐Mediated Nucleation Drives Stress Granule Assembly [PDF]
Advanced scienceLENG8 is a newly identified stress granule (SG) nucleator required for SG assembly. Following stress, nuclear LENG8 granules disassemble, allowing LENG8 to translocate into the cytoplasm and form independent nucleation foci. These foci fuse with canonical early G3BP1/TIA1 seeds via LENG8‐TIA1 binding to drive SG maturation.
Zhang M +6 more
europepmc +2 more sources
RNA-containing cytoplasmic granules in Ythdc1-deficient oocytes.
, 2018 (A) Presence of large cytoplasmic granules in oocytes from 11-week-old Ythdc1fl/- Ddx4-Cre (cKO) females. (B) Cytoplasmic granules in oocytes from 11-week-old Ythdc1fl/- Ddx4-Cre females contain RNA.
Yang Xu (178421) +7 more
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Supplementary Material for: Cytoplasmic RNA Granules in Somatic Maintenance
, 2018 Cytoplasmic RNA granules represent subcellular compartments that are enriched in protein-bound RNA species. RNA granules are produced by evolutionary divergent eukaryotes, including yeast, mammals, and plants.
Moujaber O. (5316605) +1 more
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FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Arrest of cytoplasmic streaming induces algal proliferation in green paramecia. [PDF]
PLoS ONE, 2007 A green ciliate Paramecium bursaria, bearing several hundreds of endosymbiotic algae, demonstrates rotational microtubule-based cytoplasmic streaming, in which cytoplasmic granules and endosymbiotic algae flow in a constant direction.
Toshiyuki Takahashi +3 more
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