PTEN deletion increases hippocampal granule cell excitability in male and female mice
Neurobiology of Disease, 2017 Deletion of the mTOR pathway inhibitor PTEN from postnatally-generated hippocampal dentate granule cells causes epilepsy. Here, we conducted field potential, whole cell recording and single cell morphology studies to begin to elucidate the mechanisms by ...
Victor R. Santos +9 more
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Mitral cell spike synchrony modulated by dendrodendritic synapse location
Frontiers in Computational Neuroscience, 2012 On their long lateral dendrites, mitral cells of the olfactory bulb form dendrodendritic synapses with large populations of granule cell interneurons. The mitral-granule cell microcircuit operating through these reciprocal synapses has been implicated in
Thomas S McTavish +3 more
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Cerebellar granule cells are predominantly generated by terminal symmetric divisions of granule cell precursors [PDF]
Developmental Dynamics, 2015 Background: Neurons in the central nervous system (CNS) are generated by symmetric and asymmetric cell division of neural stem cells and their derivative progenitor cells. Cerebellar granule cells are the most abundant neurons in the CNS, and are generated by intensive cell division of granule cell precursors (GCPs) during postnatal development ...
Kie, Nakashima +2 more
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Further Characterization of Dopamine Release by Permeabilized PC 12 Cells [PDF]
, 1987 Rat pheochromocytoma cells (PC 12) permeabilized with staphylococcal α-toxin release [3H]dopamine after addition of micromolar Ca2+. This does not require additional Mg2+-ATP (in contrast to bovine adrenal medullary chromaffin cells).
Ahnert-Hilger, G. +3 more
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, 2012 Denervation-induced changes in excitatory synaptic strength were studied following entorhinal deafferentation of hippocampal granule cells in mature (≥3 weeks old) mouse organotypic entorhino-hippocampal slice cultures.
Roeper, Jochen +23 more
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, 2012 During postnatal development hippocampal dentate granule cells (GCs) often extend dendrites from the basal pole of their cell bodies into the hilar region. These so-called hilar basal dendrites (hBD) usually regress with maturation.
Gerlind Schuldt +17 more
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Multimodal sensory integration in single cerebellar granule cells in vivo
eLife, 2015 The mammalian cerebellum is a highly multimodal structure, receiving inputs from multiple sensory modalities and integrating them during complex sensorimotor coordination tasks.
Taro Ishikawa +2 more
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Golgi cell-mediated activation of postsynaptic GABA(B) receptors induces disinhibition of the Golgi cell-granule cell synapse in rat cerebellum. [PDF]
PLoS ONE, 2012 In the cerebellar glomerulus, GABAergic synapses formed by Golgi cells regulate excitatory transmission from mossy fibers to granule cells through feed-forward and feedback mechanisms.
Federico Brandalise +2 more
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Ultrastructural features and synaptic connections of hilar ectopic granule cells in the rat dentate gyrus are different from those of granule cells in the granule cell layer [PDF]
, 2001 Several investigators have shown the existence of dentate granule cells in ectopic locations within the hilus and molecular layer using both Golgi and retrograde tracing studies but the ultrastructural features and synaptic connections of ectopic granule
Charles E. Ribak +9 more
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Early natural stimulation through environmental enrichment accelerates neuronal development in the mouse dentate gyrus. [PDF]
PLoS ONE, 2012 The dentate gyrus is the primary afferent into the hippocampal formation, with important functions in learning and memory. Granule cells, the principle neuronal type in the dentate gyrus, are mostly formed postnatally, in a process that continues into ...
Na Liu, Shan He, Xiang Yu
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