Results 61 to 70 of about 4,987,565 (306)
FEBS Open Bio, EarlyView.Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya +2 more
wiley +1 more source
A Hypothesis for Temporal Coding of Young and Mature Granule Cells
Frontiers in Neuroscience, 2013 While it has been hypothesized that adult neurogenesis plays a role in the encoding of temporal information at long time scales, the temporal relationship of immature cells to the highly rhythmic network activity of the hippocampus has been largely ...
Lara M Rangel +5 more
doaj +1 more source
Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins
FEBS Open Bio, EarlyView.Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley +1 more source
Synaptic Integration in Cerebellar Granule Cells
, 2008 To understand the function of cerebellar granule cells, we need detailed knowledge about the information carried by their afferent mossy fibers and how this information is integrated by the granule cells.
Jörntell, Henrik +4 more
core +2 more sources
Cadherin-2 controls directional chain migration of cerebellar granule neurons.
PLoS Biology, 2009 Long distance migration of differentiating granule cells from the cerebellar upper rhombic lip has been reported in many vertebrates. However, the knowledge about the subcellular dynamics and molecular mechanisms regulating directional neuronal migration
Sandra Rieger +3 more
doaj +1 more source
FEBS Open Bio, EarlyView.We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen +5 more
wiley +1 more source
Frontiers in Integrative Neuroscience, 2014 Golgi cells (GoCs) are specialized interneurons that provide inhibitory input to granule cells in the cerebellar cortex. GoCs are pacemaker neurons that spontaneously fire action potentials, triggering spontaneous inhibitory postsynaptic currents in ...
Paolo eBotta +2 more
doaj +1 more source
Number of cells counted for granule-content scoring.
, 2018 Number of cells counted for granule-content scoring.
Joshua B. Kelley (6090782) +4 more
core +1 more source
FEBS Open Bio, EarlyView.Glioblastoma cells express calcitonin receptor variants (CT receptor isoforms) that may help them survive stress. Using qPCR, transcript‐specific long‐read nanopore sequencing, immunofluorescence co‐localisation and comparative sequence analysis, this study identifies a novel alternatively spliced CALCR transcript that encodes the CTb receptor isoform ...
Pragya Gupta +7 more
wiley +1 more source
(A) Spike patterns of 50 granule cells when NMDA channels of granule cells were blocked
, 2011 Copyright information:Taken from "A spiking network model for passage-of-time representation in the cerebellum"The European Journal of Neuroscience 2007;26(8):2279-2292.Published online Jan 2007PMCID:PMC2228369.© The Authors (2007). Journal Compilation ©
Shigeru Tanaka (40073) +1 more
core +1 more source