Results 71 to 80 of about 4,987,565 (306)

Developmental Profile of Newly Generated Granule Cells in the Adult Rodent Dentate Gyrus [PDF]

, 2008
This chapter focuses on the newly generated dentate granule cells in the adult rodent and describes the developmental profile of their dendrites and axons. Topics covered include progenitor cell types in the adult dentate gyrus, dendritic growth of newly
Ribak, CE, Perez, ZD, Shapiro, LA, Charles E. Ribak, Lee A. Shapiro, Zachary D. Perez   +5 more
core   +1 more source

Cell surface CD11c as a neutrophil aging marker molecule

FEBS Open Bio, EarlyView.
Cell surface CD11chi neutrophils were more aged and had better phagocytic function than CD11c−/lo neutrophils. Transcriptomic analysis of CD11chi neutrophils and CD11c−/lo neutrophils in pediatric population showed that the most difference was seen in infants.
Sophia Koutsogiannaki, Fahd Alhamdan, Erik Malm, Marie Bermudez, Samuel Y. Kim, Koichi Yuki   +5 more
wiley   +1 more source

Long-term genetic fate mapping of adult generated neurons in a mouse temporal lobe epilepsy model

Neurobiology of Disease, 2012
In the epileptic brain, seizures can increase hippocampal neurogenesis, while opposingly seizure-associated brain pathology has been shown to detrimentally affect neurogenesis.
Mehrnoosh Jafari, Jonna Soerensen, Renée Marie Bogdanović, Leda Dimou, Magdalena Götz, Heidrun Potschka   +5 more
doaj   +1 more source

Ultrastructural features and synaptic connections of hilar ectopic granule cells in the rat dentate gyrus are different from those of granule cells in the granule cell layer [PDF]

, 2001
Several investigators have shown the existence of dentate granule cells in ectopic locations within the hilus and molecular layer using both Golgi and retrograde tracing studies but the ultrastructural features and synaptic connections of ectopic granule
Charles E. Ribak, Dashtipour, Khashayar, Tran, Peter H, Khashayar Dashtipour, J.Victor Nadler, Nadler, J Victor, Okazaki, Maxine M, Ribak, Charles E, Peter H. Tran, Maxine M. Okazaki   +9 more
core   +1 more source

MARK4 enhances stress granule formation under oxidative stress and increases tau accumulation

FEBS Open Bio, EarlyView.
MARK4 (red dots) localizes to stress granules (orange dots) and promotes their formation under oxidative stress by modulating TIA1 (blue dots). MARK4 and TIA1 synergistically increase tau (purple) accumulation, and the reduction of the TIA1 ortholog suppresses neurodegeneration in a fly model.
Sho Nakajima, Kotone Watanabe, Grigorii Sultanakhmetov, Aoi Fukuchi, Keiya Ito, Sawako Shimizu, Taro Saito, Akiko Asada, Kanae Ando   +8 more
wiley   +1 more source

Recent advances in understanding the mechanisms of cerebellar granule cell development and function and their contribution to behavior [version 1; referees: 3 approved]

F1000Research, 2018
The cerebellum is the focus of an emergent series of debates because its circuitry is now thought to encode an unexpected level of functional diversity. The flexibility that is built into the cerebellar circuit allows it to participate not only in motor ...
Elizabeth P. Lackey, Detlef H. Heck, Roy V. Sillitoe   +2 more
doaj   +1 more source

Peripheral Neutrophil Activation and Extracellular Trap Formation in Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
Markers of neutrophil activation are increased in plasma during ALS, and markers of NET formation associate with ALS survival. ABSTRACT Objectives Peripheral neutrophil levels in amyotrophic lateral sclerosis (ALS) inversely correlate with survival, suggesting a role for neutrophils in disease progression.
Lillia A. Baird, Haley McQuown, Jihyun Park, Samuel J. Teener, Ian F. Webber‐Davis, Andrew D. Carter, Dae‐Gyu Jang, Eva L. Feldman, Stephen A. Goutman, Benjamin J. Murdock   +9 more
wiley   +1 more source

Distinct patterns of dentate gyrus cell activation distinguish physiologic from aberrant stimuli.

PLoS ONE, 2020
Under physiologic conditions, the dentate gyrus (DG) exhibits exceptionally low levels of activity compared to other brain regions. A sparse activation pattern is observed even when the DG is engaged to process new information; for example, only ~1-3% of
Jason C You, Kavitha Muralidharan, Chia-Hsuan Fu, Jin Park, Umberto Tosi, Xiaohong Zhang, Jeannie Chin   +6 more
doaj   +1 more source

Elastic–Plastic Modeling and Experimental Characterization of Granular Jamming Actuators

Advanced Engineering Materials, EarlyView.
Granular jamming enables rapid switching between soft and rigid mechanical states. Here, a reduced‐order elastic‐perfectly‐plastic beam framework captures pressure‐dependent loading, unloading, residual deformation, and hysteresis in jammed beams, while matching three‐point bending experiments across materials and geometries. The framework links design
Saheli Patel, Prashant K. Purohit, Jordan R. Raney   +2 more
wiley   +1 more source

Population of pyramidal and granule cells in dissociated culture.

, 2015
(A) Proportion of neuronal species in cultures from different aged pups. Whole neurons, pyramidal cells and granule cells were identified as NeuN-, Math2- and Prox1-positive cells, respectively. n = 722 (E17), 508 (P0), 634 (P4).
Kazuto Fujishima (694639), Mineko Kengaku (219523), You Kure Wu (694638)   +2 more
core   +1 more source