Results 91 to 100 of about 4,987,565 (306)
Convergence of pontine and proprioceptive streams onto multimodal cerebellar granule cells
eLife, 2013 Cerebellar granule cells constitute the majority of neurons in the brain and are the primary conveyors of sensory and motor-related mossy fiber information to Purkinje cells.
Cheng-Chiu Huang +7 more
doaj +1 more source
Intrinsic Properties of EGFP-expressing and Mature Granule Cells.
, 2013 Histograms of the whole-cell capacitance, resting membrane potential and input resistance demonstrate that EGFP-expressing granule cells (green lines) are typically smaller, more depolarized (though inaccurately measured, see text) and have a higher ...
Pankaj Sah (158755) +4 more
core +1 more source
The NK cell granule protein NKG7 regulates cytotoxic granule exocytosis and inflammation
, 2020 Immune-modulating therapies have revolutionized the treatment of chronic diseases, particularly cancer. However, their success is restricted and there is a need to identify new therapeutic targets. Here, we show that natural killer cell granule protein 7
McEnroe, Benjamin A +14 more
core +1 more source
Interface Dynamics in Biomolecular Condensates by High‐Speed AFM
Advanced Materials Interfaces, EarlyView.High‐speed atomic force microscopy provides nanoscale structural dynamics at the liquid interface of biomolecular condensates, key elements in several cellular pathways. By addressing the challenges of low surface tension and condensate‐induced instabilities, we achieve nanometer spatial and sub‐second temporal resolution, revealing structural ...
Andreas Santamaria +6 more
wiley +1 more source
Scalable Fabrication of Chemically Stabilized Gelatin Hydrogel Fibers by Thermal Drawing
Advanced Materials Interfaces, EarlyView.Scalable processing of hydrogel fibers remains a major challenge. By coupling thermal drawing with Maillard chemistry, a transient viscous‐flow window is created that enables continuous fabrication of microstructured gelatin fibers tens of meters long, while continued in situ crosslinking during drawing stabilizes the fibers for physiological ...
Chaoqun Dong +5 more
wiley +1 more source
Structural changes for adult‐born dentate granule cells after status epilepticus [PDF]
, 2008 Status epilepticus (SE) not only results in an increased number of newly generated neurons in the dentate gyrus but also leads to structural alterations of many of these newborn granule cells.
Charles E. Ribak +5 more
core +1 more source
Advanced Science, EarlyView.ABSTRACT Gonadotropin‐inhibitory hormone (GnIH, also known as RFamide‐related peptide‐3, RFRP‐3) is a hypothalamic neuropeptide that regulates vertebrate reproduction via its receptor GPR147. Although GnIH is known to mediate stress‐induced reproductive suppression, its role in broader stress responses remains unclear.
Jiani Zhang +18 more
wiley +1 more source
EGFP-expressing Granule Cells Are Newborn Neurons.
, 2013 Coronal sections through the dentate gyrus were labeled with antibodies for EGFP (left panels, green channel) and proteins known to be expressed at various time points of dentate granule cell development (center panels, red channel).
Pankaj Sah (158755) +4 more
core +1 more source
Advanced Science, EarlyView.Prostate cancer is immunologically ‘cold’, with scarce, dysfunctional type 1 conventional dendritic cells (cDC1s) that limit T cell priming. We introduce an aptamer‐targeted liposomedelivering FMS‐like tyrosine kinase 3 ligand (Flt3L) and chlorin e6 (Ce6). Ultrasound induces antigen release and cDC1s recruitment, creating an in situ cDC1 vaccine.
Jiayi Wang +8 more
wiley +1 more source
, 2022 Progressive physiological changes in the hippocampal dentate gyrus circuits following traumatic brain injury (TBI) contribute to temporal evolution of neurological sequelae.
Gupta, Akshay +4 more
core +1 more source