Results 211 to 220 of about 272,903 (354)

Tissue‐specific expression of mast cell granule serine proteinases and their role in inflammation in the lung and gut

, 2002
H. R. P. Miller, Alan D. Pemberton
openalex   +1 more source

EIF5A Couples Translational Control With Transcriptional Reprogramming Through Chromocenter Reorganization During Spermiogenesis

Advanced Science, EarlyView.
The translation factor Eukaryotic translation initiation factor 5A (eIF5A) is essential for male fertility in mice. It supports the translation of proteins crucial for heterochromatin organization and acrosome formation. eIF5A deficiency disrupts chromocenter integrity, increases chromatin accessibility, and causes transcriptional dysregulation ...
Yuling Cai, Tongtong Li, Qian Fang, Ziyou Bao, Feng Kong, Huitao Qi, Hanzhen Li, Mingyu Zhang, Wei Wang, Yongxia Guan, Wenbo Liu, Xiangfeng Chen, Zi‐Jiang Chen, Xiaohua Jiang, Xin Wang, Hongbin Liu   +15 more
wiley   +1 more source

Effect of <i>L</i>-theanine on cerebellar granule cell migration related to cognitive disorders. [PDF]

IBRO Neurosci Rep
Ibrahim M, Tomoko M, Kenji K, Makoto O, Aya A, Umekawa H, Nishio M.   +6 more
europepmc   +1 more source

Prostate Cancer-associated SPOP mutations enhance cancer cell survival and docetaxel resistance by upregulating Caprin1-dependent stress granule assembly [PDF]

, 2019
Qing Shi, Yasheng Zhu, Jian Ma, Kun Chang, Dongling Ding, Yang Bai, Kun Gao, Pingzhao Zhang, Ren Mo, Kai Feng, Xiaying Zhao, Liang Zhang, Huiru Sun, Dongyue Jiao, Yingji Chen, Yinghao Sun, Shi-min Zhao, Haojie Huang, Yao Li, Shancheng Ren, Chenji Wang   +20 more
openalex   +1 more source

A Novel Enhancer-AAV Approach Selectively Targeting Dentate Granule Cells

, 2023
Emmie Banks, Claire‐Anne Gutekunst, Geoffrey Vargish, Anna Eaton, Kenneth A. Pelkey, Chris J. McBain, James Q. Zheng, Viktor Janos Oláh, Matthew JM Rowan   +8 more
openalex   +1 more source

Rod‐Shaped Nanotherapeutics Alleviate Rheumatoid Arthritis by Precisely Disrupting Platelet‐Mediated Pathological Crosstalk via a Morphology‐Dependent Manner

Advanced Science, EarlyView.
Owing to the margination effect, rod‐shaped nanoparticles exhibit markedly enhanced co‐localization with endothelial‐adherent platelets (PLTs) under dynamic blood flow. When internalized by PLTs, rod‐shaped PNR@Res inhibit FAK and PI3K/AKT signaling in a morphology‐dependent manner, thereby disrupting their pathological crosstalk with various ...
Bin Zhang, Yuanyi Hua, Xin Wen, Zhumei Liao, Jianheng Ren, Yajun Weng, Qin Wang   +6 more
wiley   +1 more source

Diversification of dentate gyrus granule cell subtypes is regulated by Nrg1 nuclear back-signaling. [PDF]

Life Sci Alliance
Rajebhosale P, Jiang L, Ressa HJ, Johnson KR, Desai NS, Jone A, Role LW, Talmage DA.   +7 more
europepmc   +1 more source

Cerebellar granule cell axons support high-dimensional representations. [PDF]

Nat Neurosci, 2021
Lanore F, Cayco-Gajic NA, Gurnani H, Coyle D, Silver RA.   +4 more
europepmc   +1 more source

A p21-activated kinase (PAK1) signaling cascade coordinately regulates F-actin remodeling and insulin granule exocytosis in pancreatic β cells

, 2012
Michael A. Kalwat, Stephanie M. Yoder, Zhanxiang Wang, Debbie C. Thurmond   +3 more
openalex   +2 more sources

Pan2‐Pan3 Complex‐Mediated Deadenylation Enforces mRNA Quality Control for Infection of the Rice Blast Fungus

Advanced Science, EarlyView.
Discovery that deadenylation, rather than transcription, acts as the rate‐limiting step for developmental timing in a plant pathogen. Evidence that P‐body integrity and mRNA decay are mechanistically coupled to rapid cellular differentiation under environmental stress. Identification of Pan2‐Pan3 as a pathogen‐specific “meta‐virulence factor” absent in
Ziwei Lv, Junting Feng, Shenxian Zhou, Zhiguang Qu, Jun Peng, Xiao‐Lin Chen, Deng Chen   +6 more
wiley   +1 more source