Results 261 to 270 of about 272,903 (354)

Cytomegalovirus infection lengthens the cell cycle of granule cell precursors during postnatal cerebellar development. [PDF]

JCI Insight
Sung CYW, Li M, Jonjic S, Sanchez V, Britt WJ.   +4 more
europepmc   +1 more source

Optical controlling reveals time-dependent roles for adult-born dentate granule cells

, 2012
Yan Gu, Maithe Arruda‐Carvalho, Jia Wang, Stephen Janoschka, Sheena A. Josselyn, Paul W. Frankland, Shaoyu Ge   +6 more
openalex   +2 more sources

Nissl granules in ‘fatigued’ nerve cells [PDF]

The Journal of Physiology, 1938
openaire   +2 more sources

gnSPADE: Incorporating Gene Network Structures Enhances Reference‐Free Deconvolution in Spatial Transcriptomics

Advanced Intelligent Systems, EarlyView.
gnSPADE integrates gene‐network structures into a probabilistic topic modeling framework to achieve reference‐free cell‐type deconvolution in spatial transcriptomics. By embedding gene connectivity within the generative process, gnSPADE enhances biological interpretability and accuracy across simulated and real datasets, revealing spatial organization ...
Aoqi Xie, Yuehua Cui
wiley   +1 more source

Septo-dentate gyrus cholinergic circuits modulate function and morphogenesis of adult neural stem cells through granule cell intermediaries. [PDF]

Proc Natl Acad Sci U S A
Chen ZK, Quintanilla L, Su Y, Sheehy RN, Simon JM, Luo YJ, Li YD, Chen Z, Asrican B, Tart DS, Farmer WT, Ming GL, Song H, Song J.   +13 more
europepmc   +1 more source

Variants in AKR1D1 and Infant Mortality: Should Bile Acid Screening be a Routine Part of Newborn Screening?

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Biallelic pathogenic variants in AKR1D1 cause Δ4‐3‐oxosteroid 5β‐reductase deficiency, disrupt bile acid synthesis, and result in Congenital Bile Acid Synthesis defect type 2 (CBAS2). CBAS2 presents in infancy with cholestasis, coagulopathy, and failure to thrive.
Jade Hudson, Stephanie Hyunh, Bojana Rakic, Cornelius Boerkoel   +3 more
wiley   +1 more source

Chorioamnionitis accelerates granule cell and oligodendrocyte maturation in the cerebellum of preterm nonhuman primates. [PDF]

J Neuroinflammation
Newman J, Tong X, Tan A, Yeasky T, De Paiva VN, Presicce P, Kannan PS, Williams K, Damianos A, Tamase Newsam M, Benny MK, Wu S, Young KC, Miller LA, Kallapur SG, Chougnet CA, Jobe AH, Brambilla R, Schmidt AF.   +18 more
europepmc   +1 more source

Multimorbidity and animal models

Animal Models and Experimental Medicine, EarlyView.
Multimorbidity, defined as the coexistence of ≥2 chronic conditions, is associated with aging, genetics, and environmental factors. Animal models in multimorbidity research span three tiers: simple organisms for initial screening → rodents for mechanistic analysis → large mammals for clinical prediction.
Xinpei Wang, Yakun Ren, Xingjiu Yang, Mengyuan Li, Junxiu Liu, Xiaoyan Du, Wen Wang, Ran Gao   +7 more
wiley   +1 more source

Local synaptic inhibition mediates cerebellar granule cell pattern separation and enables learned sensorimotor associations. [PDF]

Nat Neurosci
Fleming EA, Field GD, Tadross MR, Hull C.   +3 more
europepmc   +1 more source

Establishment of a mouse model of TMAO‐induced cardiac injury and application of MICT intervention

Animal Models and Experimental Medicine, EarlyView.
This study aims to explore the establishment of an animal model of cardiac injury induced by trimethylamine‐N‐oxide (TMAO), a metabolite secreted by gut microorganisms, and to investigate its application in moderate‐intensity continuous training (MICT) intervention.
Zhongping Xie, Hong Zou, Lijing Gong, Minghui Lin, Caihua Huang   +4 more
wiley   +1 more source