Results 291 to 300 of about 272,903 (354)

Intracellular self‐assembled nanoneedles for efficient lysosomal escape and CRISPR/Cas9 mediated gene editing

BMEMat, EarlyView.
PlaMnB was formed by cytolysin A‐tumor homing peptides (THP)‐modified bacterial membranes encapsulating the clustered regularly interspaced short palindromic repeat/CRISPR‐associated protein (CRISPR/Cas9) plasmid and manganese dioxide. THP‐containing bacterial membrane enhances PlaMnB vascular permeability and tumor targeting, and after cellular ...
Chen Zhang, Nan Zhang, Ruiqi Yang, Qian Qiu, Jiaying Huang, Jingang Liu, Silu Li, Jonathan F. Lovell, He Ren, Yumiao Zhang   +9 more
wiley   +1 more source

Dynamics of natural killer cell function upon recurrent stimulation

Biotechnology Progress, EarlyView.
Weekly stimulation of peripheral blood‐derived NK cells with engineered K562 feeder cells resulted in two distinct growth phases, shifting around Day 21–26. Cells in growth phase 2 exhibited slower growth, reduced metabolic activity, and lower cytotoxicity than cells from growth phase 1, which has implications for NK cell biomanufacturing.
Jennifer One, Janani Narayan, Frank Cichocki, Wei‐Shou Hu, Samira M. Azarin   +4 more
wiley   +1 more source

[Indole-3-acetic acid alleviates Cryptococcus neoformans-induced pyroptosis in cerebral microvascular endothelial cells by regulating stress granule-mediated NLRP3 inflammasome activation].

Jingyu Chen, Jinhu Zou, Bingliang Zhou, X. Gao, Pengwei Huang, Hong Cao   +5 more
openalex   +2 more sources

Interleukin (IL)‐5, Eosinophils and IL‐5 Pathway Inhibitors in Eosinophilic Granulomatosis with Polyangiitis.

Arthritis &Rheumatology, Accepted Article.
Alvise Berti, Christian Pagnoux
wiley   +1 more source

The Ataxin-2 protein is required in Kenyon cells for RNP-granule assembly and appetitive long-term memory formation

Hillebrand, Jens, Roselli, Camilla, Ramaswami, Mani   +2 more
openalex   +1 more source

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Purinergic Modulation of Granule Cells

The Cerebellum, 2010
Extracellular purines exert their action in the nervous system through purinergic neurotransmission and neuromodulatory processes. Among brain areas, efforts have been made to investigate the purinergic modulation of the cerebellar cortex. In addition, the use of granule cells in culture as a neuronal in vitro model provided important information about
Raphaël, Courjaret, María Teresa, Miras-Portugal, Joachim W, Deitmer   +2 more
openaire   +2 more sources

Isolation of Mast Cell Granules

Current Protocols in Cell Biology, 2005
AbstractThe mast cell is a multipotent inflammatory cell that has been shown to participate in the pathogenesis of a variety of diseases, such as immediate hypersensitivity reactions, arthritis, atherosclerosis, and heart failure. Upon stimulation, mast cells exocytose cytoplasmic secretory granules into their extracellular microenvironment.
Ken A, Lindstedt, Petri T, Kovanen
openaire   +2 more sources

Birbeck Granules (Langerhans’ Cell Granules) in Human Lymph Nodes

American Journal of Clinical Pathology, 1973
Electron microscopic examination of lymph nodes from “normal” subjects and diseased patients revealed the presence of Birbeck granules in histiocytes in 8 of 12 patients with subacute sclerosing panencephalitis (SSPE), 1 of 6 patients with other diseases, and 1 of 4 “normal” subjects. The one apparently “normal” subject who had Birbeck granules was the
M L, Vernon, L, Fountain, H M, Krebs, L, Horta-Barbosa, D A, Fuccillo, J L, Sever   +5 more
openaire   +2 more sources